CN110396040B - 一种一锅法合成二芳基甲缩酮的方法 - Google Patents
一种一锅法合成二芳基甲缩酮的方法 Download PDFInfo
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- CN110396040B CN110396040B CN201910845875.4A CN201910845875A CN110396040B CN 110396040 B CN110396040 B CN 110396040B CN 201910845875 A CN201910845875 A CN 201910845875A CN 110396040 B CN110396040 B CN 110396040B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
- C07C41/50—Preparation of compounds having groups by reactions producing groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
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- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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CN201910845875.4A CN110396040B (zh) | 2019-09-09 | 2019-09-09 | 一种一锅法合成二芳基甲缩酮的方法 |
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CN201910845875.4A CN110396040B (zh) | 2019-09-09 | 2019-09-09 | 一种一锅法合成二芳基甲缩酮的方法 |
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CN110396040A CN110396040A (zh) | 2019-11-01 |
CN110396040B true CN110396040B (zh) | 2020-12-15 |
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CN112500267A (zh) | 2020-12-04 | 2021-03-16 | 江苏慧聚药业有限公司 | 4-溴-2-(4’-乙氧基-苄基)-1-氯苯的制备 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997034860A1 (en) * | 1996-03-15 | 1997-09-25 | Consiglio Nazionale Delle Ricerche | A PROCESS FOR THE PREPARATION OF α-ARYLPROPIONIC ACIDS AND THE INTERMEDIATES THEREOF |
CN101948503A (zh) * | 2010-09-10 | 2011-01-19 | 天津金汇药业集团有限公司 | 常温均相反应制备倍他米松缩酮物的方法 |
US20170029398A1 (en) * | 2014-03-06 | 2017-02-02 | Srinivasan Thirumalai Rajan | Process for the preparation of (1s)-1,5-anhydro-1-c-{4-chloro-3-4[(4-ethoxyphenyl)methyl]phenyl]-glucitol and its solvate thereof |
CN108530408A (zh) * | 2018-04-13 | 2018-09-14 | 海门慧聚药业有限公司 | 制备达格列净的方法 |
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2019
- 2019-09-09 CN CN201910845875.4A patent/CN110396040B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997034860A1 (en) * | 1996-03-15 | 1997-09-25 | Consiglio Nazionale Delle Ricerche | A PROCESS FOR THE PREPARATION OF α-ARYLPROPIONIC ACIDS AND THE INTERMEDIATES THEREOF |
CN101948503A (zh) * | 2010-09-10 | 2011-01-19 | 天津金汇药业集团有限公司 | 常温均相反应制备倍他米松缩酮物的方法 |
US20170029398A1 (en) * | 2014-03-06 | 2017-02-02 | Srinivasan Thirumalai Rajan | Process for the preparation of (1s)-1,5-anhydro-1-c-{4-chloro-3-4[(4-ethoxyphenyl)methyl]phenyl]-glucitol and its solvate thereof |
CN108530408A (zh) * | 2018-04-13 | 2018-09-14 | 海门慧聚药业有限公司 | 制备达格列净的方法 |
Non-Patent Citations (1)
Title |
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Application of the Catalytic Friedel–Crafts Acylation Reaction and Regioselectivity Correlations;Mark C. Wilkinson等;《SYNLETT》;20061231(第7期);第1063-1066页 * |
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Address after: 210096, No. four archway, Xuanwu District, Jiangsu, Nanjing 2 Patentee after: SOUTHEAST University Patentee after: Jiangsu Huiju Pharmaceutical Co.,Ltd. Address before: 210096, No. four archway, Xuanwu District, Jiangsu, Nanjing 2 Patentee before: SOUTHEAST University Patentee before: WISDOM PHARMACEUTICAL Co.,Ltd. Address after: 210096, No. four archway, Xuanwu District, Jiangsu, Nanjing 2 Patentee after: SOUTHEAST University Patentee after: Jiangsu Huiju Pharmaceutical Co.,Ltd. Address before: 210096, No. four archway, Xuanwu District, Jiangsu, Nanjing 2 Patentee before: SOUTHEAST University Patentee before: Jiangsu Huiju Pharmaceutical Co.,Ltd. |
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