IN2013MU02527A - - Google Patents

Info

Publication number
IN2013MU02527A
IN2013MU02527A IN2527MU2013A IN2013MU02527A IN 2013MU02527 A IN2013MU02527 A IN 2013MU02527A IN 2527MU2013 A IN2527MU2013 A IN 2527MU2013A IN 2013MU02527 A IN2013MU02527 A IN 2013MU02527A
Authority
IN
India
Prior art keywords
nucleotide sequence
insulin
leader peptide
sequence encoding
terminal end
Prior art date
Application number
Other languages
English (en)
Inventor
Sanjay Sonar
Archana Krishnan
Damodar Thappa
Original Assignee
Biogenomics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenomics Ltd filed Critical Biogenomics Ltd
Priority to SG11201600684XA priority Critical patent/SG11201600684XA/en
Priority to US14/908,854 priority patent/US10000544B2/en
Priority to PCT/IN2014/000506 priority patent/WO2015015518A2/en
Priority to IN2527MU2013 priority patent/IN2013MU02527A/en
Priority to EP14789420.8A priority patent/EP3027645A2/de
Publication of IN2013MU02527A publication Critical patent/IN2013MU02527A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN2527MU2013 2013-07-31 2014-07-31 IN2013MU02527A (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SG11201600684XA SG11201600684XA (en) 2013-07-31 2014-07-31 Process for production of insulin and insulin analogues
US14/908,854 US10000544B2 (en) 2013-07-31 2014-07-31 Process for production of insulin and insulin analogues
PCT/IN2014/000506 WO2015015518A2 (en) 2013-07-31 2014-07-31 Process for production of insulin and insulin analogues
IN2527MU2013 IN2013MU02527A (de) 2013-07-31 2014-07-31
EP14789420.8A EP3027645A2 (de) 2013-07-31 2014-07-31 Verfahren zur herstellung von insulin und insulinanaloga

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2527MU2013 IN2013MU02527A (de) 2013-07-31 2014-07-31

Publications (1)

Publication Number Publication Date
IN2013MU02527A true IN2013MU02527A (de) 2015-06-26

Family

ID=51794935

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2527MU2013 IN2013MU02527A (de) 2013-07-31 2014-07-31

Country Status (5)

Country Link
US (1) US10000544B2 (de)
EP (1) EP3027645A2 (de)
IN (1) IN2013MU02527A (de)
SG (1) SG11201600684XA (de)
WO (1) WO2015015518A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115716876A (zh) * 2022-07-04 2023-02-28 北京惠之衡生物科技有限公司 一种融合蛋白及其应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3027643A2 (de) 2013-07-31 2016-06-08 Biogenomics Limited Expressionsvektor zur herstellung rekombinanter proteine in prokaryoten-wirtszellen
EP3658574A1 (de) * 2017-07-28 2020-06-03 The Trustees of Princeton University Fusions-tags für rekombinante proteinexpression
CN112105635A (zh) * 2018-06-18 2020-12-18 联合化学实验室有限公司 用于重组蛋白的更高表达的前导序列
CN112584853B (zh) * 2018-09-12 2021-12-10 美药星（南京）制药有限公司 一种新型门冬胰岛素原的结构和制备门冬胰岛素的方法
US10799564B1 (en) 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004085472A1 (en) * 2003-03-27 2004-10-07 Novo Nordisk A/S Method for making human insulin precursors and human insulin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115716876A (zh) * 2022-07-04 2023-02-28 北京惠之衡生物科技有限公司 一种融合蛋白及其应用

Also Published As

Publication number Publication date
EP3027645A2 (de) 2016-06-08
WO2015015518A3 (en) 2015-04-16
WO2015015518A2 (en) 2015-02-05
US20160168226A1 (en) 2016-06-16
SG11201600684XA (en) 2016-02-26
US10000544B2 (en) 2018-06-19

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