SG11201600684XA - Process for production of insulin and insulin analogues - Google Patents

Process for production of insulin and insulin analogues

Info

Publication number
SG11201600684XA
SG11201600684XA SG11201600684XA SG11201600684XA SG11201600684XA SG 11201600684X A SG11201600684X A SG 11201600684XA SG 11201600684X A SG11201600684X A SG 11201600684XA SG 11201600684X A SG11201600684X A SG 11201600684XA SG 11201600684X A SG11201600684X A SG 11201600684XA
Authority
SG
Singapore
Prior art keywords
insulin
production
analogues
insulin analogues
Prior art date
Application number
SG11201600684XA
Inventor
Archana Krishnan
Sanjay Sonar
Damodar Thappa
Original Assignee
Biogenomics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenomics Ltd filed Critical Biogenomics Ltd
Publication of SG11201600684XA publication Critical patent/SG11201600684XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201600684XA 2013-07-31 2014-07-31 Process for production of insulin and insulin analogues SG11201600684XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2527MU2013 IN2013MU02527A (en) 2013-07-31 2014-07-31
PCT/IN2014/000506 WO2015015518A2 (en) 2013-07-31 2014-07-31 Process for production of insulin and insulin analogues

Publications (1)

Publication Number Publication Date
SG11201600684XA true SG11201600684XA (en) 2016-02-26

Family

ID=51794935

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201600684XA SG11201600684XA (en) 2013-07-31 2014-07-31 Process for production of insulin and insulin analogues

Country Status (5)

Country Link
US (1) US10000544B2 (en)
EP (1) EP3027645A2 (en)
IN (1) IN2013MU02527A (en)
SG (1) SG11201600684XA (en)
WO (1) WO2015015518A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9803207B2 (en) 2013-07-31 2017-10-31 Biogenomics Limited Expression vector for production of recombinant proteins in prokaryotic host cells
JP2020529221A (en) * 2017-07-28 2020-10-08 ザ・トラスティーズ・オブ・プリンストン・ユニバーシティThe Trustees Of Princeton University Fusion tag for recombinant protein expression
EP3807306A4 (en) * 2018-06-18 2022-04-06 Unichem Laboratories Limited Leader sequence for higher expression of recombinant proteins
CN112584853B (en) * 2018-09-12 2021-12-10 美药星(南京)制药有限公司 Structure of novel insulin aspart and method for preparing insulin aspart
US10799564B1 (en) 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
CN115850385B (en) * 2022-07-04 2023-08-11 北京惠之衡生物科技有限公司 Expression-promoting peptide and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004085472A1 (en) * 2003-03-27 2004-10-07 Novo Nordisk A/S Method for making human insulin precursors and human insulin

Also Published As

Publication number Publication date
US20160168226A1 (en) 2016-06-16
EP3027645A2 (en) 2016-06-08
IN2013MU02527A (en) 2015-06-26
WO2015015518A3 (en) 2015-04-16
US10000544B2 (en) 2018-06-19
WO2015015518A2 (en) 2015-02-05

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