IN2013MU02133A - - Google Patents
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- Publication number
- IN2013MU02133A IN2013MU02133A IN2133MU2013A IN2013MU02133A IN 2013MU02133 A IN2013MU02133 A IN 2013MU02133A IN 2133MU2013 A IN2133MU2013 A IN 2133MU2013A IN 2013MU02133 A IN2013MU02133 A IN 2013MU02133A
- Authority
- IN
- India
- Prior art keywords
- acetoxyandrosta
- diene
- pharmaceutically acceptable
- acceptable salt
- abiraterone acetate
- Prior art date
Links
- 229960004103 abiraterone acetate Drugs 0.000 abstract 2
- UVIQSJCZCSLXRZ-UBUQANBQSA-N abiraterone acetate Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CC[C@@H](CC4=CC[C@H]31)OC(=O)C)C=C2C1=CC=CN=C1 UVIQSJCZCSLXRZ-UBUQANBQSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- MBOKKQYHTRISBA-WQBVUOOHSA-N [(8r,9s,10r,13s,14s)-10-methyl-17-(trifluoromethylsulfonyloxy)-2,3,4,7,8,9,11,12,14,15-decahydro-1h-cyclopenta[a]phenanthren-13-yl]methyl acetate Chemical compound C1CCC[C@]2(C)[C@H]3CC[C@](COC(=O)C)(C(=CC4)OS(=O)(=O)C(F)(F)F)[C@@H]4[C@@H]3CC=C21 MBOKKQYHTRISBA-WQBVUOOHSA-N 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/392,210 US20160176915A1 (en) | 2013-06-24 | 2014-06-24 | Process for preparation of abiraterone acetate |
| JP2016522965A JP2016527213A (ja) | 2013-06-24 | 2014-06-24 | アビラテロン酢酸エステルの製造方法 |
| PCT/IN2014/000420 WO2014207762A1 (en) | 2013-06-24 | 2014-06-24 | Process for preparation of abiraterone acetate |
| IN2133MU2013 IN2013MU02133A (zh) | 2013-06-24 | 2014-06-24 | |
| EP14816900.6A EP3013844A4 (en) | 2013-06-24 | 2014-06-24 | Process for preparation of abiraterone acetate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2133MU2013 IN2013MU02133A (zh) | 2013-06-24 | 2014-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013MU02133A true IN2013MU02133A (zh) | 2015-06-05 |
Family
ID=52141189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2133MU2013 IN2013MU02133A (zh) | 2013-06-24 | 2014-06-24 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20160176915A1 (zh) |
| EP (1) | EP3013844A4 (zh) |
| JP (1) | JP2016527213A (zh) |
| IN (1) | IN2013MU02133A (zh) |
| WO (1) | WO2014207762A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108948120A (zh) * | 2018-07-07 | 2018-12-07 | 张正光 | 一种醋酸阿比特龙中间体的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2742331B2 (ja) * | 1992-03-31 | 1998-04-22 | ブリテイツシユ・テクノロジー・グループ・リミテツド | 癌治療に有用な１７位置換ステロイド |
| GB0418900D0 (en) * | 2004-08-24 | 2004-09-29 | Btg Int Ltd | Novel salt forms |
| PT2428519E (pt) * | 2004-08-24 | 2015-04-29 | Btg Int Ltd | Processo para preparação de 17-o-vinil-triflatos como intermediários |
| EP2917225A1 (en) * | 2012-11-09 | 2015-09-16 | Synthon BV | Process for making abiraterone-3-acetate |
| WO2014071983A1 (en) * | 2012-11-09 | 2014-05-15 | Synthon Bv | Process for making the 17-triflate intermediate of abiraterone-3-acetate |
| EP2890705B1 (en) * | 2013-07-29 | 2016-04-13 | Industriale Chimica S.R.L. | Process for the preparation of abiraterone or abiraterone acetate |
| WO2015015246A1 (en) * | 2013-07-29 | 2015-02-05 | Industriale Chimica S.R.L. | Process for the preparation of abiraterone and abiraterone acetate |
-
2014
- 2014-06-24 JP JP2016522965A patent/JP2016527213A/ja active Pending
- 2014-06-24 IN IN2133MU2013 patent/IN2013MU02133A/en unknown
- 2014-06-24 US US14/392,210 patent/US20160176915A1/en not_active Abandoned
- 2014-06-24 WO PCT/IN2014/000420 patent/WO2014207762A1/en active Application Filing
- 2014-06-24 EP EP14816900.6A patent/EP3013844A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP3013844A4 (en) | 2017-03-01 |
| EP3013844A1 (en) | 2016-05-04 |
| WO2014207762A1 (en) | 2014-12-31 |
| US20160176915A1 (en) | 2016-06-23 |
| JP2016527213A (ja) | 2016-09-08 |
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