IN2012DN02675A - - Google Patents

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Publication number
IN2012DN02675A
IN2012DN02675A IN2675DEN2012A IN2012DN02675A IN 2012DN02675 A IN2012DN02675 A IN 2012DN02675A IN 2675DEN2012 A IN2675DEN2012 A IN 2675DEN2012A IN 2012DN02675 A IN2012DN02675 A IN 2012DN02675A
Authority
IN
India
Prior art keywords
met
cess
indazol
dicyano
pro
Prior art date
Application number
Other languages
English (en)
Inventor
Michels Martin
Follmann Markus
Vakalopoulos Alexandros
Zimmermann Katja
Teusch Nicole
Lobell Mario
Bierer Donald
Engel Karen
Kissel Maria
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of IN2012DN02675A publication Critical patent/IN2012DN02675A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/4161,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IN2675DEN2012 2009-10-06 2010-10-01 IN2012DN02675A (enrdf_load_stackoverflow)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09172304 2009-10-06
PCT/EP2010/064648 WO2011042368A1 (en) 2009-10-06 2010-10-01 Fluoro-substituted 3,5-dicyano-4-(1h-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives and methods of use thereof

Publications (1)

Publication Number Publication Date
IN2012DN02675A true IN2012DN02675A (enrdf_load_stackoverflow) 2015-09-04

Family

ID=43357944

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2675DEN2012 IN2012DN02675A (enrdf_load_stackoverflow) 2009-10-06 2010-10-01

Country Status (27)

Country Link
US (1) US9422263B2 (enrdf_load_stackoverflow)
EP (1) EP2485726B1 (enrdf_load_stackoverflow)
JP (1) JP5753175B2 (enrdf_load_stackoverflow)
KR (1) KR20120091005A (enrdf_load_stackoverflow)
CN (1) CN102573838B (enrdf_load_stackoverflow)
AR (1) AR078486A1 (enrdf_load_stackoverflow)
AU (1) AU2010305550A1 (enrdf_load_stackoverflow)
BR (1) BR112012006842A2 (enrdf_load_stackoverflow)
CA (1) CA2773676C (enrdf_load_stackoverflow)
CL (1) CL2012000753A1 (enrdf_load_stackoverflow)
CR (1) CR20120150A (enrdf_load_stackoverflow)
CU (1) CU20120051A7 (enrdf_load_stackoverflow)
DO (1) DOP2012000085A (enrdf_load_stackoverflow)
EC (1) ECSP12011748A (enrdf_load_stackoverflow)
ES (1) ES2458117T3 (enrdf_load_stackoverflow)
IL (1) IL218415A0 (enrdf_load_stackoverflow)
IN (1) IN2012DN02675A (enrdf_load_stackoverflow)
MX (1) MX2012003603A (enrdf_load_stackoverflow)
NZ (1) NZ599006A (enrdf_load_stackoverflow)
PE (1) PE20121392A1 (enrdf_load_stackoverflow)
PH (1) PH12012500640A1 (enrdf_load_stackoverflow)
RU (1) RU2012111695A (enrdf_load_stackoverflow)
SG (1) SG178990A1 (enrdf_load_stackoverflow)
TW (1) TW201124396A (enrdf_load_stackoverflow)
UY (1) UY32922A (enrdf_load_stackoverflow)
WO (1) WO2011042368A1 (enrdf_load_stackoverflow)
ZA (1) ZA201201524B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0650179Y2 (ja) 1989-06-01 1994-12-21 株式会社プラコー ブロー成形機用のダイヘッド
JPH0756186Y2 (ja) 1989-07-24 1995-12-25 株式会社日本製鋼所 パリソンの押出成形装置
JP2781376B2 (ja) 1996-06-17 1998-07-30 エクセル株式会社 中空成形品
DE102009056886A1 (de) * 2009-12-03 2011-06-09 Bayer Schering Pharma Aktiengesellschaft cMet-Inhibitoren zur Behandlung der Endometriose

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3635977A (en) 1969-11-03 1972-01-18 American Cyanamid Co Certain 6-trifluoromethylcytosines and thiocytosines their synthesis and their use in the synthesis of uracisls and thiouracil
DE59009485D1 (de) 1989-01-26 1995-09-14 Bayer Ag Optisch aktive (Meth)Acrylsäure-Derivate, ihre Herstellung, ihre Polymerisation zu optisch aktiven Polymeren und deren Verwendung.
DE19546136A1 (de) 1995-12-11 1997-06-12 Bayer Ag Chirale stationäre Phasen für die chromatographische Trennung von optischen Isomeren
KR20050004214A (ko) 2002-05-31 2005-01-12 에자이 가부시키가이샤 피라졸 화합물 및 이것을 포함하여 이루어지는 의약 조성물
JP2007526324A (ja) 2004-03-02 2007-09-13 スミスクライン・ビーチャム・コーポレイション Akt活性のある阻害剤
EP1722792A1 (de) 2004-03-03 2006-11-22 Boehringer Ingelheim International GmbH Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
AU2005316511B2 (en) 2004-12-13 2009-12-03 Irm Llc Compounds and compositions as modulators of steroidal receptors and calcium channel activities
WO2006074419A2 (en) 2005-01-07 2006-07-13 Roskamp Research Llc Compounds for inhibiting beta-amyloid production and methods of identifying the compounds
US7632839B2 (en) * 2005-01-19 2009-12-15 Merck & Co. Inc. Mitotic kinesin inhibitors
CN101558040B (zh) 2006-12-14 2013-03-27 拜耳先灵医药股份有限公司 用作蛋白激酶抑制剂的二氢吡啶衍生物

Also Published As

Publication number Publication date
HK1172835A1 (en) 2013-05-03
SG178990A1 (en) 2012-04-27
DOP2012000085A (es) 2012-07-15
AR078486A1 (es) 2011-11-09
CL2012000753A1 (es) 2012-09-14
NZ599006A (en) 2013-11-29
ECSP12011748A (es) 2012-05-30
PE20121392A1 (es) 2012-10-14
WO2011042368A1 (en) 2011-04-14
ES2458117T3 (es) 2014-04-30
RU2012111695A (ru) 2013-10-10
CR20120150A (es) 2012-08-03
US20120264785A1 (en) 2012-10-18
JP5753175B2 (ja) 2015-07-22
KR20120091005A (ko) 2012-08-17
BR112012006842A2 (pt) 2016-06-07
PH12012500640A1 (en) 2012-11-12
CU20120051A7 (es) 2012-06-29
CN102573838A (zh) 2012-07-11
IL218415A0 (en) 2012-04-30
JP2013506699A (ja) 2013-02-28
EP2485726A1 (en) 2012-08-15
CN102573838B (zh) 2014-09-24
UY32922A (es) 2011-04-29
US9422263B2 (en) 2016-08-23
CA2773676A1 (en) 2011-04-14
EP2485726B1 (en) 2014-03-12
CA2773676C (en) 2017-07-04
ZA201201524B (en) 2013-05-29
AU2010305550A1 (en) 2012-03-29
MX2012003603A (es) 2012-04-20
TW201124396A (en) 2011-07-16

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