IN2012DN00797A - - Google Patents

Download PDF

Info

Publication number
IN2012DN00797A
IN2012DN00797A IN797DEN2012A IN2012DN00797A IN 2012DN00797 A IN2012DN00797 A IN 2012DN00797A IN 797DEN2012 A IN797DEN2012 A IN 797DEN2012A IN 2012DN00797 A IN2012DN00797 A IN 2012DN00797A
Authority
IN
India
Prior art keywords
relates
present
monoclonal antibody
antibody
aureus
Prior art date
Application number
Other languages
English (en)
Inventor
Michael Rudolf
Holger Koch
Original Assignee
Kenta Biotech Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kenta Biotech Ag filed Critical Kenta Biotech Ag
Publication of IN2012DN00797A publication Critical patent/IN2012DN00797A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins
    • A61K49/16Antibodies; Immunoglobulins; Fragments thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
IN797DEN2012 2009-08-10 2010-08-10 IN2012DN00797A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09010311A EP2284193A1 (fr) 2009-08-10 2009-08-10 Anticorps monoclonal humain contre l'alpha-toxine dérivée du Staphylococcus aureus, et son utilisation pour le traitement ou la prévention de la formation des abcès
US26633009P 2009-12-03 2009-12-03
PCT/EP2010/004884 WO2011018208A1 (fr) 2009-08-10 2010-08-10 Anticorps monoclonal humain contre l’alpha-toxine dérivée de s. aureus et son utilisation dans le traitement ou la prévention de la formation d’abcès

Publications (1)

Publication Number Publication Date
IN2012DN00797A true IN2012DN00797A (fr) 2015-06-26

Family

ID=41381987

Family Applications (1)

Application Number Title Priority Date Filing Date
IN797DEN2012 IN2012DN00797A (fr) 2009-08-10 2010-08-10

Country Status (11)

Country Link
US (1) US9249215B2 (fr)
EP (3) EP2284193A1 (fr)
JP (1) JP6064241B2 (fr)
KR (1) KR101836130B1 (fr)
CN (1) CN102549013B (fr)
CA (1) CA2769394C (fr)
ES (2) ES2529175T3 (fr)
IL (1) IL217746A (fr)
IN (1) IN2012DN00797A (fr)
RU (1) RU2529946C9 (fr)
WO (1) WO2011018208A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140286960A1 (en) * 2011-07-28 2014-09-25 Cangene Corporation Staphlococcus aureus alpha-hemolysin antibodies
WO2013093693A1 (fr) * 2011-12-22 2013-06-27 Rinat Neuroscience Corp. Anticorps spécifiques de staphylococcus aureus et leurs utilisations
PL2668208T3 (pl) 2012-04-17 2015-12-31 Arsanis Biosciences Gmbh Krzyżowo reaktywne przeciwciało rozpoznające Staphylococcus aureus
KR20210083389A (ko) * 2012-11-06 2021-07-06 메디뮨 엘엘씨 에스.아우레우스 연관 질병의 치료 방법
SG11201503232TA (en) * 2012-11-06 2015-05-28 Medimmune Llc Antibodies to s. aureus surface determinants
CN104211804A (zh) * 2014-08-20 2014-12-17 钱泓 一种抗金黄色葡萄球菌多克隆抗体的制备与应用
TW202311284A (zh) 2017-01-03 2023-03-16 美商再生元醫藥公司 抗金黃色葡萄球菌溶血素a毒素之人類抗體
AU2020290971A1 (en) * 2019-06-14 2021-12-23 Dana-Farber Cancer Institute, Inc. Antibodies against PD-1 and methods of use thereof
CN112538112B (zh) * 2019-09-20 2023-10-27 迈威(上海)生物科技股份有限公司 抗α-溶血素的抗体及其应用
CN113444171A (zh) 2020-03-25 2021-09-28 兴盟生物医药(苏州)有限公司 金黄色葡萄球菌α-毒素特异性抗体及其应用
US20230374114A1 (en) * 2020-04-16 2023-11-23 Dana-Farber Cancer Institute, Inc. Coronavirus antibodies and methods of use thereof
CN113698478A (zh) * 2020-05-21 2021-11-26 迈威(上海)生物科技股份有限公司 抗α-溶血素的抗体及其稳定制剂
WO2023208123A1 (fr) * 2022-04-28 2023-11-02 珠海泰诺麦博制药股份有限公司 Anticorps monoclonal entièrement humain se liant spécifiquement à la toxine hla de staphylococcus aureus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0950068B1 (fr) * 1996-05-16 2005-11-09 THE TEXAS A&M UNIVERSITY SYSTEM Compositions de proteine de liaison du collagene et procedes d'utilisation
CA2654712C (fr) * 2006-06-06 2015-05-05 Crucell Holland B.V. Molecules de liaison humaines presentant une activite bactericide contre les staphylocoques et leurs utilisations
US20090053235A1 (en) 2006-06-12 2009-02-26 Nabi Biopharmaceuticals Use of alpha-toxin for treating and preventing staphylococcus infections
WO2009029831A1 (fr) * 2007-08-31 2009-03-05 University Of Chicago Procédés et compositions associées pour immuniser contre des maladies et des états staphylococciques des poumons

Also Published As

Publication number Publication date
ES2651762T3 (es) 2018-01-29
WO2011018208A1 (fr) 2011-02-17
KR20120047270A (ko) 2012-05-11
CN102549013A (zh) 2012-07-04
JP6064241B2 (ja) 2017-01-25
CA2769394C (fr) 2019-06-25
IL217746A (en) 2016-05-31
ES2529175T3 (es) 2015-02-17
JP2013501506A (ja) 2013-01-17
RU2529946C9 (ru) 2015-03-27
CA2769394A1 (fr) 2011-02-17
IL217746A0 (en) 2012-03-29
RU2529946C2 (ru) 2014-10-10
EP2464665B1 (fr) 2014-12-03
EP2860191B1 (fr) 2017-10-11
EP2284193A1 (fr) 2011-02-16
EP2860191A1 (fr) 2015-04-15
RU2012105045A (ru) 2013-09-20
US9249215B2 (en) 2016-02-02
EP2464665A1 (fr) 2012-06-20
KR101836130B1 (ko) 2018-03-08
US20120201829A1 (en) 2012-08-09
CN102549013B (zh) 2015-05-06

Similar Documents

Publication Publication Date Title
IN2012DN00797A (fr)
PH12017500864A1 (en) Anti-notch1 antibodies
MY178926A (en) Bispecific anti-vegf/anti-ang-2 antibodies
MX2020004503A (es) Anticuerpos cd3 humanizados o quimericos.
IL214884A (en) Two-specific, three-valent antibody, pharmaceutical preparations containing it and nucleic acids encoding it
WO2010115552A8 (fr) Anticorps anti-erbb-3/anti-c-met bispécifiques
MX340558B (es) Anticuerpos biespecificos que comprenden fragmento fv estabilizado con disulfuro.
MY162825A (en) Antibodies for epidermal growth factor receptor 3 (her3)
MX2016008098A (es) Anticuerpos biespecificos del receptor 2 de factor de crecimiento ipidermico himano (her2) y metodo de uso.
MX2010005682A (es) Anticuerpos bivalentes, biespecificos.
MX2010006396A (es) Anticuerpos bivalentes, biespecificos.
MX2010005888A (es) Anticuerpos bivalentes biespecificos.
UA100874C2 (en) Bivalent bispecific antibodies
MX336682B (es) Anticuerpos contra csf-1r humanos y usos de los mismos.
IL212633A (en) A monoclonal antibody or its antigen-binding portion, its pharmaceutical preparations and its use in the preparation of cancer drugs
SG178886A1 (en) Humanized anti-cdcp1 antibodies
UA106070C2 (uk) Антитіло, що специфічно зв'язується з egfr і her3
MX362039B (es) Anticuerpos anti-il-23.
PH12014502406B1 (en) Anti-il-23p19 antibodies
EA201291067A1 (ru) Гуманизированные антигенсвязывающие белки к миостатину
EA201001639A1 (ru) Композиции и способы их получения и применения
AU2011217848A8 (en) Integrin aVB8 neutralizing antibody
UA106529C2 (uk) Гуманізоване антитіло до cxcr4 для лікування раку
JO3437B1 (ar) أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
MX2013001267A (es) ANTICUERPOS A IL-1ß E EIL-18 PARA TRATAMIENTO DE ENFERMEDAD.