IN2012DN00581A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN00581A IN2012DN00581A IN581DEN2012A IN2012DN00581A IN 2012DN00581 A IN2012DN00581 A IN 2012DN00581A IN 581DEN2012 A IN581DEN2012 A IN 581DEN2012A IN 2012DN00581 A IN2012DN00581 A IN 2012DN00581A
- Authority
- IN
- India
- Prior art keywords
- compositions
- generation
- methods
- stem cells
- pluripotent stem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/145—Thrombopoietin [TPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21861109P | 2009-06-19 | 2009-06-19 | |
PCT/US2010/039222 WO2010148334A2 (en) | 2009-06-19 | 2010-06-18 | Generation of induced pluripotent stem cells from cord blood |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN00581A true IN2012DN00581A (ko) | 2015-06-12 |
Family
ID=43357075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN581DEN2012 IN2012DN00581A (ko) | 2009-06-19 | 2010-06-18 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20110044961A1 (ko) |
EP (1) | EP2443231A4 (ko) |
JP (1) | JP2012530497A (ko) |
KR (1) | KR20120099363A (ko) |
CN (1) | CN102712903A (ko) |
AU (1) | AU2010263055A1 (ko) |
CA (1) | CA2766049A1 (ko) |
IL (1) | IL217063A0 (ko) |
IN (1) | IN2012DN00581A (ko) |
RU (1) | RU2012101874A (ko) |
SG (1) | SG176925A1 (ko) |
WO (1) | WO2010148334A2 (ko) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2952805C (en) | 2009-06-05 | 2021-06-01 | Cellular Dynamics International, Inc. | Reprogramming t cells and hematopoietic cells |
US20120301438A1 (en) * | 2009-09-14 | 2012-11-29 | The Johns Hopkins University | Reprogramming Blood Cells to Pluripotent and Multipotent Stem Cells |
US20130202649A1 (en) * | 2012-01-17 | 2013-08-08 | The Board Of Trustees Of The Leland Stanford Junior University | Activation of innate immunity for nuclear reprogramming of somatic cells |
US11767507B2 (en) | 2013-11-08 | 2023-09-26 | The Mclean Hospital Corporation | Methods for efficient generation of GABAergic interneurons from pluripotent stem cells |
GB201704953D0 (en) | 2017-03-28 | 2017-05-10 | Imp Innovations Ltd | Natural killer cells |
US11572544B2 (en) | 2017-06-14 | 2023-02-07 | The Children's Medical Center Corporation | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells by episomal plasmid gene transfer |
US11834757B2 (en) | 2017-12-06 | 2023-12-05 | New York Blood Center, Inc. | HLA homozygous induced pluripotent stem cell (iPSC) libraries |
AU2021211713A1 (en) | 2020-01-23 | 2022-08-25 | The Children's Medical Center Corporation | Stroma-free T cell differentiation from human pluripotent stem cells |
WO2023285529A1 (en) | 2021-07-13 | 2023-01-19 | Arne Jensen | Method of producing immortalized clonal mesenchymal stem cells (hmscs) from hla homozygous human induced pluripotent stem cells (hipsc's) derived from cord blood |
WO2023285533A1 (en) | 2021-07-13 | 2023-01-19 | Arne Jensen | Method of producing exosomes from immortalized clonal mesenchymal stem cells (hmscs) derived from hla homozygous human induced pluripotent stem cells (hipsc's) derived from cord blood |
WO2023285536A1 (en) | 2021-07-13 | 2023-01-19 | Arne Jensen | Exosomes derived from immortalized mesenchymal stromal cells (hmscs) for use as a medicament |
CN113699183A (zh) * | 2021-08-06 | 2021-11-26 | 温州医科大学 | 一种标记及追踪cd133阳性室管膜细胞的重组质粒、构建方法及鉴定方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1176189A1 (en) * | 2000-07-21 | 2002-01-30 | Fornix Biosciences N.V. | Stem cell-like cells |
WO2008151058A2 (en) * | 2007-05-30 | 2008-12-11 | The General Hospital Corporation | Methods of generating pluripotent cells from somatic cells |
JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
US20120076762A1 (en) * | 2009-03-25 | 2012-03-29 | The Salk Institute For Biological Studies | Induced pluripotent stem cell generation using two factors and p53 inactivation |
-
2010
- 2010-06-18 CN CN201080035756XA patent/CN102712903A/zh active Pending
- 2010-06-18 KR KR1020127001626A patent/KR20120099363A/ko not_active Application Discontinuation
- 2010-06-18 RU RU2012101874/10A patent/RU2012101874A/ru unknown
- 2010-06-18 EP EP10790286A patent/EP2443231A4/en not_active Withdrawn
- 2010-06-18 JP JP2012516345A patent/JP2012530497A/ja active Pending
- 2010-06-18 SG SG2011094232A patent/SG176925A1/en unknown
- 2010-06-18 AU AU2010263055A patent/AU2010263055A1/en not_active Abandoned
- 2010-06-18 IN IN581DEN2012 patent/IN2012DN00581A/en unknown
- 2010-06-18 US US12/819,059 patent/US20110044961A1/en not_active Abandoned
- 2010-06-18 CA CA2766049A patent/CA2766049A1/en not_active Abandoned
- 2010-06-18 WO PCT/US2010/039222 patent/WO2010148334A2/en active Application Filing
-
2011
- 2011-12-18 IL IL217063A patent/IL217063A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
SG176925A1 (en) | 2012-01-30 |
KR20120099363A (ko) | 2012-09-10 |
JP2012530497A (ja) | 2012-12-06 |
WO2010148334A2 (en) | 2010-12-23 |
CN102712903A (zh) | 2012-10-03 |
RU2012101874A (ru) | 2013-07-27 |
IL217063A0 (en) | 2012-02-29 |
CA2766049A1 (en) | 2010-12-23 |
EP2443231A4 (en) | 2013-02-27 |
AU2010263055A1 (en) | 2012-02-23 |
US20110044961A1 (en) | 2011-02-24 |
EP2443231A2 (en) | 2012-04-25 |
WO2010148334A3 (en) | 2011-05-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2012DN00581A (ko) | ||
WO2010111409A3 (en) | Pluripotent stem cells | |
ZA201606403B (en) | Pluripotent stem cell culture on micro-carriers | |
WO2010111422A3 (en) | Induced pluripotent stem cell generation using two factors and p53 inactivation | |
EP2421956A4 (en) | COMPOSITIONS AND METHODS FOR OBTAINING OR CULTURING PLURIPOTENTER CELLS | |
SG196784A1 (en) | Stem cell cultures | |
IL214798A0 (en) | Methods and compositions for stem cell cultures | |
EP2373784A4 (en) | GENERATION AND MAINTENANCE OF STEM CELLS | |
ZA201202685B (en) | Methods of preparing mesenchymal stem cells,compositions and kit thereof | |
EP2487236A4 (en) | CULTURE SUPPORT FOR HUMAN PLURIPOTENTE STEM CELLS AND USE THEREOF | |
MY159971A (en) | Multipotent/pluripotent cells and methods | |
FI20096288A0 (fi) | Formulations and methods for culturing stem cells | |
EP2435558A4 (en) | PRODUCTION OF HEAVY INDUCED PLURIPOTENT STEM CELLS GENERALLY CORRECTED | |
EP2440652A4 (en) | METHOD FOR CULTIVATING STEM CELLS AND PRECURSOR CELLS | |
MX2010000348A (es) | Cultivo de celulas madre pluripotentes individuales. | |
PL2162534T3 (pl) | Genetycznie zmodyfikowane, mezenchymalne komórki macierzyste CD34 negatywne do leczenia nowotworów | |
MY179933A (en) | Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use thereof | |
UA118328C2 (uk) | Спосіб інтегрування екзогенних послідовностей у геном рослинної клітини | |
SG10201500674YA (en) | Pluripotent stem cells | |
EP2494032A4 (en) | GENERATION OF INDUCED PLURIPOTENTER STEM CELLS AND FIBROBLAST PRECURSOR CELLS | |
IL219454A (en) | Multipotent stem cells isolated from extrahepatic biliary tree and their isolation and use | |
EP2387609A4 (en) | Nonembryonic stem cells and their use | |
IN2012DN00852A (ko) | ||
EP2424978A4 (en) | COMPOSITIONS AND METHODS FOR STEM CELL MODULATION AND ITS APPLICATIONS | |
WO2011100286A3 (en) | Compositions and methods of generating a differentiated mesodermal cell |