IN2012DN00551A - - Google Patents

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Publication number
IN2012DN00551A
IN2012DN00551A IN551DEN2012A IN2012DN00551A IN 2012DN00551 A IN2012DN00551 A IN 2012DN00551A IN 551DEN2012 A IN551DEN2012 A IN 551DEN2012A IN 2012DN00551 A IN2012DN00551 A IN 2012DN00551A
Authority
IN
India
Prior art keywords
radioimmunoconjugate
relates
methods
radioimmvmoconjugate
hum195
Prior art date
Application number
Other languages
English (en)
Inventor
Simon Jaime
Gaylord King A
Manuel Moreno Bermudez Josue
Original Assignee
Actinium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actinium Pharmaceuticals Inc filed Critical Actinium Pharmaceuticals Inc
Publication of IN2012DN00551A publication Critical patent/IN2012DN00551A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN551DEN2012 2009-07-22 2010-07-22 IN2012DN00551A (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22771009P 2009-07-22 2009-07-22
PCT/US2010/042885 WO2011011592A1 (en) 2009-07-22 2010-07-22 Methods for generating radioimmunoconjugates

Publications (1)

Publication Number Publication Date
IN2012DN00551A true IN2012DN00551A (https=) 2015-06-12

Family

ID=43499411

Family Applications (1)

Application Number Title Priority Date Filing Date
IN551DEN2012 IN2012DN00551A (https=) 2009-07-22 2010-07-22

Country Status (8)

Country Link
US (1) US9603954B2 (https=)
EP (1) EP2456472B1 (https=)
JP (2) JP5985392B2 (https=)
CN (2) CN104710504B (https=)
CA (1) CA2768658C (https=)
IN (1) IN2012DN00551A (https=)
RU (2) RU2704802C2 (https=)
WO (1) WO2011011592A1 (https=)

Families Citing this family (18)

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GB201208309D0 (en) * 2012-05-11 2012-06-27 Algeta As Complexes
US20150157742A1 (en) * 2013-12-11 2015-06-11 The European Atomic Energy Community (Euratom), Represented By The European Commission SYNTHESIS OF BIOLOGICAL COMPOUNDS LABELED WITH THE ALPHA EMITTER Ac-225
CA2949365A1 (en) * 2014-05-16 2015-11-19 Memorial Sloan Kettering Cancer Center One-step labeling of antibodies to high specific activity with actinium-225
CN108348604B (zh) * 2015-09-08 2022-04-29 沃特世科技公司 用于分析抗体-药物缀合物的多维色谱方法
US11896683B2 (en) 2016-12-16 2024-02-13 The Australian National University Radiolabelled material for targeted administration
DK3568205T3 (da) 2017-01-12 2023-10-09 Radiomedix Inc Behandling af cancerceller, der overeksprimerer somatostatinreceptorer ved at anvende radioisotop-chelaterede ocreotid-derivater
EP3661557B1 (en) * 2017-07-31 2025-09-03 Actinium Pharmaceuticals, Inc. Treatments for a hematological malignancy
CN109550061A (zh) * 2017-09-26 2019-04-02 南京江原安迪科正电子研究发展有限公司 一种用于放射性核素标记抗体的试剂盒及应用
WO2022056354A1 (en) * 2020-09-11 2022-03-17 Actinium Pharmaceuticals, Inc. Trophoblast glycoprotein radioimmunotherapy for the treatment of solid cancers
US12551584B1 (en) 2020-12-07 2026-02-17 Actinium Pharmaceuticals, Inc. Lewis Y radioimmunotherapy for the treatment of cancer
US12447218B1 (en) * 2021-02-09 2025-10-21 Actinium Pharmaceuticals, Inc. Radioconjugates directed to MHC-complexed antigens in cancer
US20250339571A1 (en) * 2021-08-27 2025-11-06 Actinium Pharmaceuticals, Inc. Radioimmunoconjugates targeting phosphatidylserine for use in the treatment of cancer
WO2023183927A2 (en) 2022-03-24 2023-09-28 Actinium Pharmaceuticals, Inc. Humanized anti-cd45 antibodies
US20250177583A1 (en) 2022-03-30 2025-06-05 Nihon Medi-Physics Co., Ltd. Method for producing complex
EP4536278A2 (en) 2022-06-07 2025-04-16 Actinium Pharmaceuticals, Inc. Bifunctional chelators and conjugates
AU2023330110A1 (en) 2022-08-22 2025-03-06 Abdera Therapeutics Inc. Dll3 binding molecules and uses thereof
US20250388688A1 (en) 2024-04-04 2025-12-25 Ethyreal Bio, Inc. Anti-tshr antibodies and uses thereof
US12600794B2 (en) 2024-07-23 2026-04-14 Abdera Therapeutics Inc. 5T4 binding polypeptides and uses thereof

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Also Published As

Publication number Publication date
CA2768658A1 (en) 2011-01-27
CN102596258B (zh) 2015-01-28
CN104710504B (zh) 2019-09-13
RU2704802C2 (ru) 2019-10-31
RU2015137512A (ru) 2018-12-25
JP2016199583A (ja) 2016-12-01
EP2456472A4 (en) 2014-08-27
RU2565402C2 (ru) 2015-10-20
RU2012106301A (ru) 2013-08-27
HK1211304A1 (en) 2016-05-20
EP2456472A1 (en) 2012-05-30
RU2015137512A3 (https=) 2019-04-02
EP2456472C0 (en) 2024-03-27
CA2768658C (en) 2018-04-03
WO2011011592A1 (en) 2011-01-27
JP2013500258A (ja) 2013-01-07
CN104710504A (zh) 2015-06-17
US20120220754A1 (en) 2012-08-30
JP5985392B2 (ja) 2016-09-06
EP2456472B1 (en) 2024-03-27
US9603954B2 (en) 2017-03-28
CN102596258A (zh) 2012-07-18

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