IN2012DE00794A - - Google Patents
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- Publication number
- IN2012DE00794A IN2012DE00794A IN794DE2012A IN2012DE00794A IN 2012DE00794 A IN2012DE00794 A IN 2012DE00794A IN 794DE2012 A IN794DE2012 A IN 794DE2012A IN 2012DE00794 A IN2012DE00794 A IN 2012DE00794A
- Authority
- IN
- India
- Prior art keywords
- liphagane
- meroterpenoid
- scaffold
- anticancer activity
- pi3k
- Prior art date
Links
- 230000001093 anti-cancer Effects 0.000 abstract 2
- 102000010400 1-phosphatidylinositol-3-kinase activity proteins Human genes 0.000 abstract 1
- 108091007960 PI3Ks Proteins 0.000 abstract 1
- 238000012925 biological evaluation Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN794DE2012 IN2012DE00794A (pl) | 2012-03-19 | 2013-03-18 | |
US14/385,808 US9206201B2 (en) | 2012-03-19 | 2013-03-18 | Boronic acid bearing liphagane compounds as inhibitors of P13K-α and/or β |
JP2015501053A JP6126197B2 (ja) | 2012-03-19 | 2013-03-18 | PI3K−α及び/又はβの阻害剤としてのボロン酸をもったリファゲイン化合物 |
EP13723567.7A EP2828269B1 (en) | 2012-03-19 | 2013-03-18 | Boronic acid bearing liphagane compounds as inhibitors of pi3k-alpha and/or beta |
CN201380026291.5A CN104395325B (zh) | 2012-03-19 | 2013-03-18 | 带有硼酸的LIPHAGANE化合物作为PI3K-α和/或β的抑制剂 |
CA2867452A CA2867452C (en) | 2012-03-19 | 2013-03-18 | Boronic acid bearing liphagane compounds as inhibitors of pi3k-.alpha. and/or .beta. |
PCT/IN2013/000169 WO2013140417A1 (en) | 2012-03-19 | 2013-03-18 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-α AND/OR β |
TW102109708A TWI577687B (zh) | 2012-03-19 | 2013-03-19 | 作為PI3K-α及/或β抑制劑之帶有硼酸之立費烷(LIPHAGANE)化合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN794DE2012 IN2012DE00794A (pl) | 2012-03-19 | 2013-03-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DE00794A true IN2012DE00794A (pl) | 2015-08-21 |
Family
ID=48464053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN794DE2012 IN2012DE00794A (pl) | 2012-03-19 | 2013-03-18 |
Country Status (8)
Country | Link |
---|---|
US (1) | US9206201B2 (pl) |
EP (1) | EP2828269B1 (pl) |
JP (1) | JP6126197B2 (pl) |
CN (1) | CN104395325B (pl) |
CA (1) | CA2867452C (pl) |
IN (1) | IN2012DE00794A (pl) |
TW (1) | TWI577687B (pl) |
WO (1) | WO2013140417A1 (pl) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7260912B2 (ja) | 2017-05-02 | 2023-04-19 | 国立大学法人東北大学 | リファガールの類縁体、及びリファガール又はその類縁体を含む多標的キナーゼ阻害剤 |
JP2019099537A (ja) * | 2017-12-07 | 2019-06-24 | コニカミノルタ株式会社 | 含窒素複素環化合物の製造方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006081659A1 (en) * | 2005-02-01 | 2006-08-10 | The University Of British Columbia | Meroterpenoid inhibitors of phosphoinositide 3 kinase (pi3k) |
GB2465405A (en) * | 2008-11-10 | 2010-05-19 | Univ Basel | Triazine, pyrimidine and pyridine analogues and their use in therapy |
-
2013
- 2013-03-18 CA CA2867452A patent/CA2867452C/en active Active
- 2013-03-18 CN CN201380026291.5A patent/CN104395325B/zh active Active
- 2013-03-18 EP EP13723567.7A patent/EP2828269B1/en active Active
- 2013-03-18 WO PCT/IN2013/000169 patent/WO2013140417A1/en active Application Filing
- 2013-03-18 JP JP2015501053A patent/JP6126197B2/ja active Active
- 2013-03-18 IN IN794DE2012 patent/IN2012DE00794A/en unknown
- 2013-03-18 US US14/385,808 patent/US9206201B2/en active Active
- 2013-03-19 TW TW102109708A patent/TWI577687B/zh active
Also Published As
Publication number | Publication date |
---|---|
JP2015514701A (ja) | 2015-05-21 |
US20150051173A1 (en) | 2015-02-19 |
JP6126197B2 (ja) | 2017-05-10 |
EP2828269B1 (en) | 2018-05-16 |
WO2013140417A1 (en) | 2013-09-26 |
US9206201B2 (en) | 2015-12-08 |
WO2013140417A4 (en) | 2013-11-21 |
TWI577687B (zh) | 2017-04-11 |
CA2867452C (en) | 2020-04-14 |
TW201341391A (zh) | 2013-10-16 |
CA2867452A1 (en) | 2013-09-26 |
CN104395325A (zh) | 2015-03-04 |
CN104395325B (zh) | 2016-12-07 |
EP2828269A1 (en) | 2015-01-28 |
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