IN2012DE00794A - - Google Patents

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Publication number
IN2012DE00794A
IN2012DE00794A IN794DE2012A IN2012DE00794A IN 2012DE00794 A IN2012DE00794 A IN 2012DE00794A IN 794DE2012 A IN794DE2012 A IN 794DE2012A IN 2012DE00794 A IN2012DE00794 A IN 2012DE00794A
Authority
IN
India
Prior art keywords
liphagane
meroterpenoid
scaffold
anticancer activity
pi3k
Prior art date
Application number
Other languages
English (en)
Inventor
A Vishwakarma Ram
Damodhar Sawant Sanghapal
Pal Singh Parvinder
Hamid Dar Abid
Raj Sharma Parduman
Kumar Saxena Ajit
Nargotra Amit
Yaaravid Kumar Kollurunajane
Ramesh Mudduddla
Khurshid Qazi Asif
Hussain Ashiq
Chanauria Nayan
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Priority to CN201380026291.5A priority Critical patent/CN104395325B/zh
Priority to EP13723567.7A priority patent/EP2828269B1/en
Priority to PCT/IN2013/000169 priority patent/WO2013140417A1/en
Priority to IN794DE2012 priority patent/IN2012DE00794A/en
Priority to JP2015501053A priority patent/JP6126197B2/ja
Priority to US14/385,808 priority patent/US9206201B2/en
Priority to CA2867452A priority patent/CA2867452C/en
Priority to TW102109708A priority patent/TWI577687B/zh
Publication of IN2012DE00794A publication Critical patent/IN2012DE00794A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN794DE2012 2012-03-19 2013-03-18 IN2012DE00794A (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CN201380026291.5A CN104395325B (zh) 2012-03-19 2013-03-18 带有硼酸的LIPHAGANE化合物作为PI3K-α和/或β的抑制剂
EP13723567.7A EP2828269B1 (en) 2012-03-19 2013-03-18 Boronic acid bearing liphagane compounds as inhibitors of pi3k-alpha and/or beta
PCT/IN2013/000169 WO2013140417A1 (en) 2012-03-19 2013-03-18 BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-α AND/OR β
IN794DE2012 IN2012DE00794A (es) 2012-03-19 2013-03-18
JP2015501053A JP6126197B2 (ja) 2012-03-19 2013-03-18 ＰＩ３Ｋ−α及び／又はβの阻害剤としてのボロン酸をもったリファゲイン化合物
US14/385,808 US9206201B2 (en) 2012-03-19 2013-03-18 Boronic acid bearing liphagane compounds as inhibitors of P13K-α and/or β
CA2867452A CA2867452C (en) 2012-03-19 2013-03-18 Boronic acid bearing liphagane compounds as inhibitors of pi3k-.alpha. and/or .beta.
TW102109708A TWI577687B (zh) 2012-03-19 2013-03-19 作為ＰＩ３Ｋ－α及／或β抑制劑之帶有硼酸之立費烷（ＬＩＰＨＡＧＡＮＥ）化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN794DE2012 IN2012DE00794A (es) 2012-03-19 2013-03-18

Publications (1)

Publication Number Publication Date
IN2012DE00794A true IN2012DE00794A (es) 2015-08-21

Family

ID=48464053

Family Applications (1)

Application Number Title Priority Date Filing Date
IN794DE2012 IN2012DE00794A (es) 2012-03-19 2013-03-18

Country Status (8)

Country Link
US (1) US9206201B2 (es)
EP (1) EP2828269B1 (es)
JP (1) JP6126197B2 (es)
CN (1) CN104395325B (es)
CA (1) CA2867452C (es)
IN (1) IN2012DE00794A (es)
TW (1) TWI577687B (es)
WO (1) WO2013140417A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018203564A1 (ja) 2017-05-02 2018-11-08 国立大学法人東北大学 リファガールの類縁体、及びリファガール又はその類縁体を含む多標的キナーゼ阻害剤
JP2019099537A (ja) * 2017-12-07 2019-06-24 コニカミノルタ株式会社 含窒素複素環化合物の製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006081659A1 (en) * 2005-02-01 2006-08-10 The University Of British Columbia Meroterpenoid inhibitors of phosphoinositide 3 kinase (pi3k)
GB2465405A (en) * 2008-11-10 2010-05-19 Univ Basel Triazine, pyrimidine and pyridine analogues and their use in therapy

Also Published As

Publication number Publication date
CA2867452C (en) 2020-04-14
US9206201B2 (en) 2015-12-08
WO2013140417A4 (en) 2013-11-21
TW201341391A (zh) 2013-10-16
EP2828269A1 (en) 2015-01-28
JP2015514701A (ja) 2015-05-21
TWI577687B (zh) 2017-04-11
JP6126197B2 (ja) 2017-05-10
CN104395325B (zh) 2016-12-07
CA2867452A1 (en) 2013-09-26
CN104395325A (zh) 2015-03-04
US20150051173A1 (en) 2015-02-19
EP2828269B1 (en) 2018-05-16
WO2013140417A1 (en) 2013-09-26

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