IN167549B - - Google Patents
Info
- Publication number
- IN167549B IN167549B IN555/MAS/88A IN555MA1988A IN167549B IN 167549 B IN167549 B IN 167549B IN 555MA1988 A IN555MA1988 A IN 555MA1988A IN 167549 B IN167549 B IN 167549B
- Authority
- IN
- India
- Prior art keywords
- cis
- trans
- treating
- oxathiolan
- methylspiro
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D497/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Photoreceptors In Electrophotography (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8479987A | 1987-08-13 | 1987-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN167549B true IN167549B (xx) | 1990-11-10 |
Family
ID=22187277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN555/MAS/88A IN167549B (xx) | 1987-08-13 | 1988-08-02 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0303391B1 (xx) |
| JP (1) | JP2877231B2 (xx) |
| KR (1) | KR920005115B1 (xx) |
| AT (1) | ATE123496T1 (xx) |
| AU (1) | AU607247B2 (xx) |
| CA (1) | CA1336601C (xx) |
| DE (1) | DE3853931T2 (xx) |
| DK (1) | DK174430B1 (xx) |
| ES (1) | ES2074440T3 (xx) |
| IL (1) | IL87234A (xx) |
| IN (1) | IN167549B (xx) |
| NO (1) | NO169391C (xx) |
| NZ (1) | NZ225660A (xx) |
| ZA (1) | ZA885643B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4876260A (en) * | 1987-10-28 | 1989-10-24 | State Of Israel, Israel Institute Of Biological Research | Oxathiolanes |
| US5534520A (en) * | 1990-04-10 | 1996-07-09 | Fisher; Abraham | Spiro compounds containing five-membered rings |
| US5852029A (en) * | 1990-04-10 | 1998-12-22 | Israel Institute For Biological Research | Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity |
| US5571918A (en) * | 1994-05-19 | 1996-11-05 | Ishihara Sangyo Kaisha Ltd. | Method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine |
| JP2852608B2 (ja) * | 1994-06-27 | 1999-02-03 | 雪印乳業株式会社 | 口腔乾燥症治療剤 |
| EP0984970B1 (en) | 1997-05-30 | 2003-11-19 | Neurosearch A/S | Spiro-quinuclidine derivatives, their preparation and use |
| US9034891B2 (en) | 2009-01-26 | 2015-05-19 | Israel Institute For Biological Research | Bicyclic heterocyclic spiro compounds |
| RU2506266C2 (ru) * | 2009-01-26 | 2014-02-10 | Израэл Инститьют Фо Байолоджикал Рисерч | Бициклические гетероциклические спиросоединения |
| CN101798311A (zh) * | 2010-04-07 | 2010-08-11 | 天津炜杰凯华科技有限公司 | 顺式西维美林的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4855290A (en) * | 1985-05-10 | 1989-08-08 | State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research | Derivatives of quinuclidine |
| ZA868369B (en) * | 1986-01-10 | 1987-11-25 | Israel State | Derivatives of quinuclidine |
| JP2529576B2 (ja) * | 1987-07-10 | 1996-08-28 | 石原産業株式会社 | トランス型２−メチルスピロ（１，３−オキサチオラン−５，３▲’▼）キヌクリジンの異性化方法 |
| JP2529577B2 (ja) * | 1987-08-13 | 1996-08-28 | 石原産業株式会社 | トランス型２−メチルスピロ（１，３−オキサチオラン−５，３▲’▼）キヌクリジン又はこれらの酸付加塩の異性化方法 |
| JPH0816111B2 (ja) * | 1987-07-21 | 1996-02-21 | 石原産業株式会社 | トランス型２−メチルスピロ（１，３−オキサチオラン−５，３’）キヌクリジン又はこれらの酸付加塩の異性化方法 |
-
1988
- 1988-07-27 IL IL87234A patent/IL87234A/xx not_active IP Right Cessation
- 1988-08-01 ZA ZA885643A patent/ZA885643B/xx unknown
- 1988-08-02 NZ NZ225660A patent/NZ225660A/xx unknown
- 1988-08-02 IN IN555/MAS/88A patent/IN167549B/en unknown
- 1988-08-03 DE DE3853931T patent/DE3853931T2/de not_active Expired - Lifetime
- 1988-08-03 AT AT88307162T patent/ATE123496T1/de not_active IP Right Cessation
- 1988-08-03 ES ES88307162T patent/ES2074440T3/es not_active Expired - Lifetime
- 1988-08-03 EP EP88307162A patent/EP0303391B1/en not_active Expired - Lifetime
- 1988-08-04 CA CA000573877A patent/CA1336601C/en not_active Expired - Lifetime
- 1988-08-08 AU AU20551/88A patent/AU607247B2/en not_active Expired
- 1988-08-10 JP JP63198124A patent/JP2877231B2/ja not_active Expired - Lifetime
- 1988-08-11 KR KR1019880010263A patent/KR920005115B1/ko not_active IP Right Cessation
- 1988-08-11 DK DK198804509A patent/DK174430B1/da not_active IP Right Cessation
- 1988-08-12 NO NO883605A patent/NO169391C/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2074440T3 (es) | 1995-09-16 |
| ZA885643B (en) | 1989-07-26 |
| DE3853931D1 (de) | 1995-07-13 |
| IL87234A (en) | 1992-02-16 |
| EP0303391A2 (en) | 1989-02-15 |
| CA1336601C (en) | 1995-08-08 |
| KR920005115B1 (ko) | 1992-06-26 |
| JP2877231B2 (ja) | 1999-03-31 |
| AU2055188A (en) | 1989-02-16 |
| DK174430B1 (da) | 2003-03-03 |
| ATE123496T1 (de) | 1995-06-15 |
| DK450988D0 (da) | 1988-08-11 |
| EP0303391B1 (en) | 1995-06-07 |
| KR890003377A (ko) | 1989-04-14 |
| AU607247B2 (en) | 1991-02-28 |
| NO169391B (no) | 1992-03-09 |
| NZ225660A (en) | 1990-06-26 |
| NO883605L (no) | 1989-02-14 |
| NO169391C (no) | 1992-06-17 |
| EP0303391A3 (en) | 1989-04-12 |
| NO883605D0 (no) | 1988-08-12 |
| DE3853931T2 (de) | 1995-10-19 |
| JPH0222280A (ja) | 1990-01-25 |
| DK450988A (da) | 1989-02-14 |
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