IL98460A0 - Heterocyclic anthracyclinone and anthracycline analogs - Google Patents

Heterocyclic anthracyclinone and anthracycline analogs

Info

Publication number
IL98460A0
IL98460A0 IL98460A IL9846091A IL98460A0 IL 98460 A0 IL98460 A0 IL 98460A0 IL 98460 A IL98460 A IL 98460A IL 9846091 A IL9846091 A IL 9846091A IL 98460 A0 IL98460 A0 IL 98460A0
Authority
IL
Israel
Prior art keywords
anthracyclinone
heterocyclic
anthracycline analogs
anthracycline
analogs
Prior art date
Application number
IL98460A
Other languages
English (en)
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of IL98460A0 publication Critical patent/IL98460A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Forms Removed On Construction Sites Or Auxiliary Members Thereof (AREA)
IL98460A 1990-06-11 1991-06-11 Heterocyclic anthracyclinone and anthracycline analogs IL98460A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53610790A 1990-06-11 1990-06-11

Publications (1)

Publication Number Publication Date
IL98460A0 true IL98460A0 (en) 1992-07-15

Family

ID=24137175

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98460A IL98460A0 (en) 1990-06-11 1991-06-11 Heterocyclic anthracyclinone and anthracycline analogs

Country Status (18)

Country Link
EP (1) EP0533744A1 (cs)
JP (1) JPH06504034A (cs)
CN (1) CN1058781A (cs)
AP (1) AP340A (cs)
AU (1) AU653348B2 (cs)
CA (1) CA2085120A1 (cs)
CS (1) CS178691A3 (cs)
FI (1) FI925611A7 (cs)
HU (1) HU9203720D0 (cs)
IE (1) IE911965A1 (cs)
IL (1) IL98460A0 (cs)
MA (1) MA22178A1 (cs)
NZ (1) NZ238490A (cs)
PL (1) PL297164A1 (cs)
PT (1) PT97931A (cs)
WO (1) WO1991019725A2 (cs)
YU (1) YU103391A (cs)
ZA (1) ZA914452B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736523A (en) * 1992-11-09 1998-04-07 Biochem Pharma Inc. Antineoplastic heteronapthoquinones
EP0659190A1 (en) * 1992-11-09 1995-06-28 Biochem Pharma Inc Antineoplastic heteronaphthoquinones
US5606037A (en) * 1992-11-09 1997-02-25 Biochem Pharma Inc. Processes antineoplastic heteronaphthoquinones
WO1995012588A1 (en) * 1993-11-05 1995-05-11 Biochem Pharma Inc. Antineoplastic heteronaphthoquinones
IT1271689B (it) * 1994-08-04 1997-06-04 Menarini Farma Ind 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
JP2021534196A (ja) 2018-08-23 2021-12-09 シージェン インコーポレイテッド 抗ｔｉｇｉｔ抗体
CN111087377B (zh) * 2020-03-19 2020-06-26 广东省微生物研究所（广东省微生物分析检测中心） 苯并异色满醌类化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030315B2 (ja) * 1976-06-01 1985-07-16 三井東圧化学株式会社 ４−ハロゲノメチルイソクマリン誘導体の製造法
JPS52148088A (en) * 1976-06-01 1977-12-08 Richardson Merrell Inc 111aminoalkylmorphansridinee 111ols
GB2067552B (en) * 1980-01-16 1984-02-29 Erba Farmitalia Anthracyline derivatives
PH25651A (en) * 1986-05-21 1991-08-21 Duphar Int Res New di, tetrahydroisoquinoline derivatives

Also Published As

Publication number Publication date
AU653348B2 (en) 1994-09-29
CN1058781A (zh) 1992-02-19
WO1991019725A2 (en) 1991-12-26
HU9203720D0 (en) 1993-03-29
FI925611A0 (fi) 1992-12-10
PT97931A (pt) 1992-03-31
AP9100278A0 (en) 1991-07-31
CS178691A3 (en) 1992-01-15
AU8097391A (en) 1992-01-07
CA2085120A1 (en) 1991-12-12
JPH06504034A (ja) 1994-05-12
NZ238490A (en) 1994-03-25
ZA914452B (en) 1992-06-24
EP0533744A1 (en) 1993-03-31
FI925611L (fi) 1992-12-10
WO1991019725A3 (en) 1992-04-30
IE911965A1 (en) 1991-12-18
YU103391A (sh) 1994-04-05
MA22178A1 (fr) 1991-12-31
PL297164A1 (cs) 1992-10-05
AP340A (en) 1994-05-13
FI925611A7 (fi) 1992-12-10

Similar Documents

Publication Publication Date Title
EP0440950A3 (en) Halogenallyl-azolyl derivatives
HU912356D0 (en) Rapacmycine derivatives
EP0470466A3 (en) Halogenalkyl-azolyl derivatives
ZA9172B (en) Azaoxindole derivatives
HRP930485A2 (en) Hiv-inhibiting benzenacetamide derivatives
EP0485984A3 (en) Diarylmethoxypiperidine derivatives
AP9100308A0 (en) Carboxymethylcyclopropane derivatives
EP0290744A3 (en) Anthracycline compounds and use thereof
GB2246045B (en) Improved multi-keying circuitry
GB2249963B (en) Face shield
ZA914452B (en) Heterocyclic anthracyclinone and anthracycline analogs
GB9007569D0 (en) Carbo-nucleoside derivatives
EP0440949A3 (en) Halogenallyl-azolyl derivatives
GB2215332B (en) New 4-demethyl-4-0-(p-fluorobenzensulfonyl)-anthracycline glycosides
GB8408453D0 (en) Anthracycline derivatives
GB2212154B (en) New 4-demethoxy anthracycline derivatives
GB2247885B (en) 13-Dihydro-3'-(2-alkoxy-4-morpholinyl)anthracyclines
EP0453883A3 (en) 2-amino-4-trichloropyridine derivatives
EP0410366A3 (en) Anthracycline derivatives
GB2249094B (en) Hetero-imidazodiazepine derivatives
GB8313651D0 (en) Anthracycline derivatives
EP0449346A3 (en) 4-piperidinyl-ergoline derivatives
IE883034L (en) Anthracyclines
IE900849L (en) Anthracycline glycosides
IE880811L (en) Anthracycline glycosides