IL97934A - איזומריזציה פוטוכימית של תרכבות אורגניות לשם קבלת תרכבות פרהויטמין d או תרכבות ויטמין d - Google Patents

איזומריזציה פוטוכימית של תרכבות אורגניות לשם קבלת תרכבות פרהויטמין d או תרכבות ויטמין d

Info

Publication number
IL97934A
IL97934A IL9793491A IL9793491A IL97934A IL 97934 A IL97934 A IL 97934A IL 9793491 A IL9793491 A IL 9793491A IL 9793491 A IL9793491 A IL 9793491A IL 97934 A IL97934 A IL 97934A
Authority
IL
Israel
Prior art keywords
group
alkyl
substituted
amino
photosensitizer
Prior art date
Application number
IL9793491A
Other languages
English (en)
Other versions
IL97934A0 (en
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of IL97934A0 publication Critical patent/IL97934A0/xx
Publication of IL97934A publication Critical patent/IL97934A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL9793491A 1990-04-27 1991-04-24 איזומריזציה פוטוכימית של תרכבות אורגניות לשם קבלת תרכבות פרהויטמין d או תרכבות ויטמין d IL97934A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90201071 1990-04-27

Publications (2)

Publication Number Publication Date
IL97934A0 IL97934A0 (en) 1992-06-21
IL97934A true IL97934A (he) 1996-09-12

Family

ID=8205006

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9793491A IL97934A (he) 1990-04-27 1991-04-24 איזומריזציה פוטוכימית של תרכבות אורגניות לשם קבלת תרכבות פרהויטמין d או תרכבות ויטמין d

Country Status (12)

Country Link
US (1) US5252191A (he)
EP (1) EP0454204B1 (he)
JP (1) JP2945505B2 (he)
AT (1) ATE124394T1 (he)
CA (1) CA2041135C (he)
CZ (1) CZ287447B6 (he)
DE (1) DE69110739T2 (he)
DK (1) DK0454204T3 (he)
ES (1) ES2073661T3 (he)
GR (1) GR3017441T3 (he)
IL (1) IL97934A (he)
SK (1) SK281371B6 (he)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5543016A (en) * 1991-07-12 1996-08-06 Inrad Photoconversion of steroids in microreactors
US5578636A (en) * 1994-04-08 1996-11-26 Purdue Research Foundation Polythiophene anti-tumor agents
ITFI940095A1 (it) * 1994-05-23 1995-11-23 Molteni & C Coniugati fotodinamici aventi proprieta' biocide
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
EP1007035A4 (en) * 1996-11-26 2000-11-22 Purdue Research Foundation POLYTHIOPHENES AS ANTITUARY AGENTS
JP2002516306A (ja) 1998-05-29 2002-06-04 ボーン ケア インターナショナル インコーポレイテッド ヒドロキシ−２５−エン−ビタミンｄ化合物の製造方法
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
US20040186082A1 (en) * 2003-03-20 2004-09-23 Hartman Raymond A. Enhanced phototherapy for the treatment of cancer and autoimmune disease
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
EP1928822B1 (en) 2005-09-26 2013-02-27 Life Technologies Corporation Violet laser excitable dyes and their method of use
CA2807419C (en) * 2010-08-18 2019-09-24 Sunil Kumar Kc Diketones and hydroxyketones as catenin signaling pathway activators
AU2014218720B2 (en) 2013-02-22 2018-09-27 Samumed, Llc Gamma-diketones as Wnt/beta -catenin signaling pathway activators
WO2016029021A1 (en) 2014-08-20 2016-02-25 Samumed, Llc Gamma-diketones for treatment and prevention of aging skin and wrinkles
CA3137162A1 (en) * 2019-05-10 2020-11-19 Fermenta Biotech Limited Irradiation process of pro vitamin d
US20220298106A1 (en) * 2019-05-15 2022-09-22 Fermenta Biotech Limited Improved photochemical synthesis of vitamin d3 using sensitizers
CA3136920A1 (en) * 2019-06-06 2020-12-10 Fermenta Biotech Limited An improved process to synthesize 5-(3-pyridyl)-2,2'-bithiophene(sensitizer)
CA3136913A1 (en) * 2019-07-09 2021-01-14 Fermenta Biotech Limited Improved, cost effective process for synthesis of vitamin d3 and its analogue calcifediol from ergosterol
WO2021005618A1 (en) * 2019-07-09 2021-01-14 Fermenta Biotech Limited Synthesis of cholesterol and vitamin d3 from phytosterols
WO2021019558A1 (en) * 2019-07-30 2021-02-04 Fermenta Biotech Limited An efficient method for synthesis of 5-(3-pyridyl)-2,2'-bithiophene(sensitizer)
WO2021019559A1 (en) * 2019-07-30 2021-02-04 Fermenta Biotech Limited Synthesis of 5-(3-pyridyl)-2,2'-bithiophene(sensitizer)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551214A (en) * 1983-07-01 1985-11-05 Hoffmann-La Roche Inc. Photochemical preparation of previtamin D
DE3346175A1 (de) * 1983-12-21 1985-07-11 Merck Patent Gmbh, 6100 Darmstadt Pyridylthiophene
US4686023A (en) * 1985-11-26 1987-08-11 Solarchem Research, Division Of Brolor Investments, Ltd. Sensitized photochemical preparation of vitamin D
NO872850L (no) * 1986-07-09 1988-01-11 Solarchem Res Fotokjemisk sensitiverende materialer.
US5089365A (en) * 1987-10-07 1992-02-18 Fuji Electric Co., Ltd. Photosensitive member for electrophotography with thiophene containing moiety on charge transport compound
US4886625A (en) * 1987-10-29 1989-12-12 Miles Inc. Functionalized conducting polymers and their use in diagnostic devices
ATE90075T1 (de) * 1988-12-12 1993-06-15 Duphar Int Res Verfahren zur photochemischen umwandlung von tachysterol-derivaten in praevitamin d-derivate und von transvitamin d-derivaten in cisvitamin d- derivate.

Also Published As

Publication number Publication date
JPH04225951A (ja) 1992-08-14
DE69110739T2 (de) 1995-11-23
CA2041135A1 (en) 1991-10-28
IL97934A0 (en) 1992-06-21
CA2041135C (en) 2003-02-11
ES2073661T3 (es) 1995-08-16
DK0454204T3 (da) 1995-08-28
JP2945505B2 (ja) 1999-09-06
CZ287447B6 (cs) 2000-11-15
SK281371B6 (sk) 2001-03-12
CS114991A3 (en) 1992-01-15
EP0454204B1 (en) 1995-06-28
EP0454204A3 (en) 1992-10-07
DE69110739D1 (de) 1995-08-03
ATE124394T1 (de) 1995-07-15
US5252191A (en) 1993-10-12
GR3017441T3 (en) 1995-12-31
EP0454204A2 (en) 1991-10-30

Similar Documents

Publication Publication Date Title
EP0454204B1 (en) Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer
Katritzky et al. Preparation, lithiation and transformation of N‐(benzotriazol‐1‐ylmethyl) heterocycles
US7595407B2 (en) Boron complexation strategy for use in manipulating 1-acyldipyrromethanes
Trofimov et al. Pyrroles and N-vinylpyrroles from ketones and acetylenes: Recent strides
MX2007013450A (es) Procedimniento de preparacion de oxindoles y tio-oxindoles 3,3-disustituidos.
Katritzky et al. Facile Synthesis of 2-Substituted Indoles and Indolo [3, 2-b] carbazoles from 2-(Benzotriazol-1-ylmethyl) indole
CA2863467C (en) Process for the preparation of phenyl substituted 3-difluoromethyl-1-methyl-1h-pyrazole-4-carboxylic acid n-methoxy- [1-methyl-2-phenylethyl] amides
Denißen et al. Sequential palladium catalyzed coupling–cyclocondensation–coupling (C 3) four-component synthesis of intensively blue luminescent biarylsubstituted pyrazoles
US7282582B2 (en) Boron complexation strategy for use in manipulating 1-acyldipyrromethanes
Datta et al. Stereoselective total synthesis of (−)-deoxoprosophylline
Chang et al. Chemistry of diazoacenaphthenones and diazoacenaphthenes
Yoshimatsu et al. Convenient preparation of 4-arylmethyl-and 4-hetarylmethyl thiazoles by regioselective cycloaddition reactions of 3-sulfanyl-and selanylpropargyl alcohols
Scanlan et al. Preparation of β-and γ-lactams from carbamoyl radicals derived from oxime oxalate amides
CA1134361A (fr) Derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent
Roman Generation of a structurally diverse library through alkylation and ring closure reactions using 3-dimethylamino-1-(thiophen-2-yl) propan-1-one hydrochloride
Kurian Synthesis of new cyclazines and 4, 5-diaryl-1 H-pyrrol-3 (2 H)-one units in discoipyrroles from indolizinone-DMAD cycloadducts
CA2256247C (fr) Nouveaux composes heterocycliques, leur procede de praparation et les compositions pharmaceutiques qui les contiennent
JP5481739B2 (ja) アルツハイマー病治療薬
Wang et al. Developments in the chemistry of 1, 3a, 6a-triazapentalenes and their fused analogs
Li et al. Photochemical electrocyclization and leaving group expulsion with a naphthothiophene-2-carboxanilide linked to a chromophore
Yamamura et al. An efficient novel synthesis of β-(azuleno [1, 2-b] benzothienyl)-and β-(azuleno [2, 1-b] benzothienyl)-α, β-unsaturated ketones by the tropylium ion-mediated intramolecular furan ring-opening reaction and X-ray investigation of methyl ketone derivative 1
WO2019106029A1 (en) Molecular solar energy storage
Hassner et al. The Cycloaddition of Vinylaziridines with Unsaturated Substrates
JP7337818B2 (ja) ピリリウム塩の製造方法
Al‐Smadi et al. New many fold 1, 2, 3‐selenadiazole aromatic derivatives

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees