IL97557A0 - Process for the isolation and expression of the human ciliary neuronotrophic factor by recombinant dna technology - Google Patents

Process for the isolation and expression of the human ciliary neuronotrophic factor by recombinant dna technology

Info

Publication number
IL97557A0
IL97557A0 IL97557A IL9755791A IL97557A0 IL 97557 A0 IL97557 A0 IL 97557A0 IL 97557 A IL97557 A IL 97557A IL 9755791 A IL9755791 A IL 9755791A IL 97557 A0 IL97557 A0 IL 97557A0
Authority
IL
Israel
Prior art keywords
isolation
expression
recombinant dna
dna technology
human ciliary
Prior art date
Application number
IL97557A
Other languages
English (en)
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT4155790A external-priority patent/IT1239272B/it
Priority claimed from IT04165590A external-priority patent/IT1243286B/it
Application filed by Fidia Spa filed Critical Fidia Spa
Publication of IL97557A0 publication Critical patent/IL97557A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL97557A 1990-03-14 1991-03-14 Process for the isolation and expression of the human ciliary neuronotrophic factor by recombinant dna technology IL97557A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT4155790A IT1239272B (it) 1990-03-14 1990-03-14 Processo per l'isolamento di un segmento di dna che codifica il fattore neuronotrofico ciliare umano
IT04165590A IT1243286B (it) 1990-07-17 1990-07-17 Processo per isolamento ed espressione del fattore neuronotrofico ciliare umano mediante la tecnologia del dna ricombinante.

Publications (1)

Publication Number Publication Date
IL97557A0 true IL97557A0 (en) 1992-06-21

Family

ID=26329124

Family Applications (1)

Application Number Title Priority Date Filing Date
IL97557A IL97557A0 (en) 1990-03-14 1991-03-14 Process for the isolation and expression of the human ciliary neuronotrophic factor by recombinant dna technology

Country Status (11)

Country Link
EP (1) EP0446931A1 (de)
JP (1) JPH04218374A (de)
KR (1) KR910016921A (de)
CN (1) CN1057295A (de)
AR (1) AR243237A1 (de)
AU (1) AU7291891A (de)
CA (1) CA2038208A1 (de)
HU (1) HUT62033A (de)
IL (1) IL97557A0 (de)
NO (1) NO911025L (de)
PL (1) PL289413A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
IL98304A (en) * 1990-06-01 2008-08-07 Regeneron Pharma The ciliary neurotrophic factor receptor
IT1247150B (it) * 1991-01-21 1994-12-12 Fidia Spa Processo per la sintesi e la purificazione del fattore neuronotroficociliare umano (cntf) da escherichia coli.
JPH07500725A (ja) * 1991-07-23 1995-01-26 シンテックス−シナージェン　ニューロサイエンス　ジョイント　ベンチャー 組換え毛様体向神経因子およびｃ−末端切断毛様体向神経因子の精製ならびに末梢神経障害の処置方法
CA2123234A1 (en) * 1991-11-11 1993-05-27 Lanfranco Callegaro Synthesis and purification of truncated and mutein forms of human ciliary neuronotrophic factor
US6472178B1 (en) 1998-02-27 2002-10-29 Regeneron Pharmaceuticals, Inc. Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
US6890901B2 (en) 1996-09-27 2005-05-10 Jagotec Ag Hyaluronic drug delivery system
US6680291B1 (en) 1998-02-27 2004-01-20 Regeneron Pharmaceuticals, Inc. Modified ciliary neurotrophic factor, method of making and methods of use thereof
ES2322882B1 (es) * 2006-10-25 2010-04-22 Lipotec Sa Peptidos inhibidores de la exocitosis neuronal.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141856A (en) * 1989-01-05 1992-08-25 Synergen, Inc. Expression of purified ciliary neurotrophic factor

Also Published As

Publication number Publication date
AU7291891A (en) 1991-09-19
HUT62033A (en) 1993-03-29
CA2038208A1 (en) 1991-09-15
NO911025D0 (no) 1991-03-14
AR243237A1 (es) 1993-07-30
EP0446931A1 (de) 1991-09-18
JPH04218374A (ja) 1992-08-07
KR910016921A (ko) 1991-11-05
HU910840D0 (en) 1991-09-30
PL289413A1 (en) 1992-02-24
CN1057295A (zh) 1991-12-25
NO911025L (no) 1991-09-16

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