IL95578A - A vaccine made from polysaccharide and protein - Google Patents

A vaccine made from polysaccharide and protein

Info

Publication number
IL95578A
IL95578A IL9557890A IL9557890A IL95578A IL 95578 A IL95578 A IL 95578A IL 9557890 A IL9557890 A IL 9557890A IL 9557890 A IL9557890 A IL 9557890A IL 95578 A IL95578 A IL 95578A
Authority
IL
Israel
Prior art keywords
streptococcus
group
protein
proteins
antigen
Prior art date
Application number
IL9557890A
Other languages
English (en)
Hebrew (he)
Other versions
IL95578A0 (en
Inventor
James L Michel
Dennis L Kasper
Frederick M Ausubel
Original Assignee
Gen Hospital Corp
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp, Brigham & Womens Hospital filed Critical Gen Hospital Corp
Publication of IL95578A0 publication Critical patent/IL95578A0/xx
Publication of IL95578A publication Critical patent/IL95578A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL9557890A 1989-09-15 1990-09-04 A vaccine made from polysaccharide and protein IL95578A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40803689A 1989-09-15 1989-09-15

Publications (2)

Publication Number Publication Date
IL95578A0 IL95578A0 (en) 1991-06-30
IL95578A true IL95578A (en) 1998-08-16

Family

ID=23614587

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9557890A IL95578A (en) 1989-09-15 1990-09-04 A vaccine made from polysaccharide and protein

Country Status (22)

Country Link
EP (1) EP0491865B1 (fr)
JP (2) JPH05500455A (fr)
KR (1) KR0180559B1 (fr)
AT (1) ATE146081T1 (fr)
AU (1) AU641439B2 (fr)
CA (2) CA2383393A1 (fr)
DE (1) DE69029396T2 (fr)
DK (1) DK0491865T3 (fr)
ES (1) ES2097154T3 (fr)
FI (1) FI105154B (fr)
GR (1) GR1002294B (fr)
HU (1) HU219327B (fr)
IE (1) IE903349A1 (fr)
IL (1) IL95578A (fr)
NO (1) NO313908B1 (fr)
NZ (1) NZ235316A (fr)
PL (3) PL167444B1 (fr)
PT (1) PT95316A (fr)
RU (1) RU2113234C1 (fr)
WO (1) WO1991004049A1 (fr)
YU (1) YU176490A (fr)
ZA (1) ZA907297B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648241A (en) 1989-09-15 1997-07-15 The General Hospital Corporation Conjugate vaccine against group B streptococcus
NZ248766A (en) * 1992-09-24 1996-11-26 Ca Nat Research Council Capsular polysaccharide-protein conjugate vaccine against group b streptococcus type ii or v
ZA937034B (en) * 1992-09-24 1995-06-23 Brigham & Womens Hospital Group B streptococcus type II and type V polysaccharide-protein conjugate vaccines
IL107458A0 (en) * 1992-11-02 1994-02-27 Gen Hospital Corp Conjugate vaccine against group b streptococcus
AU722078B2 (en) * 1992-11-02 2000-07-20 Brigham And Women's Hospital Conjugate vaccine against group B Streptococcus
CN1046291C (zh) * 1993-03-19 1999-11-10 G·林达尔 Rib蛋白、其纯化方法、检测试剂盒及药物组合物
US6015889A (en) 1993-03-19 2000-01-18 Gunnar Lindahl Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
WO1999033969A1 (fr) * 1997-12-31 1999-07-08 Pincus Seth H Technique permettant d'isoler un peptide imunologiquement mimetique de glucides microbiens, et notamment des glucides des streptocoques du groupe b, et utilisation dudit peptide dans un vaccin
MX2007007033A (es) * 2004-12-22 2007-08-03 Novartis Vaccines & Diagnostic Estreptococus del grupo b.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367222A (en) * 1980-06-09 1983-01-04 President And Fellows Of Harvard College Immune globulin specific to Group B streptococci
US4367223A (en) * 1980-06-09 1983-01-04 President And Fellows Of Harvard College Vaccine against Group B streptococci
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
NZ214503A (en) * 1984-12-20 1990-02-26 Merck & Co Inc Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates
EP0302887B1 (fr) * 1986-04-16 1994-06-22 The Brigham And Women's Hospital, Inc. Antigenes, anticorps, vaccins bacteriens et leur procede de production
WO1989000583A1 (fr) * 1987-07-17 1989-01-26 Xoma Corporation Therapies ameliorees a base d'immunotoxines utilisant des especes a chaine-a de ricine purifiee

Also Published As

Publication number Publication date
PL286898A1 (en) 1991-06-03
NO920942D0 (no) 1992-03-11
AU641439B2 (en) 1993-09-23
IL95578A0 (en) 1991-06-30
FI105154B (fi) 2000-06-30
EP0491865A4 (en) 1993-05-05
IE903349A1 (en) 1991-04-10
PL167444B1 (pl) 1995-09-30
HUT63770A (en) 1993-10-28
NO313908B1 (no) 2002-12-23
KR920703097A (ko) 1992-12-17
JP3447713B2 (ja) 2003-09-16
ATE146081T1 (de) 1996-12-15
GR900100692A (el) 1992-01-20
PL167882B1 (pl) 1995-11-30
DE69029396D1 (de) 1997-01-23
ES2097154T3 (es) 1997-04-01
EP0491865B1 (fr) 1996-12-11
AU6519090A (en) 1991-04-18
NO920942L (no) 1992-05-12
RU2113234C1 (ru) 1998-06-20
WO1991004049A1 (fr) 1991-04-04
CA2066221C (fr) 2002-07-23
ZA907297B (en) 1993-06-01
EP0491865A1 (fr) 1992-07-01
JP2001309795A (ja) 2001-11-06
FI921111A0 (fi) 1992-03-13
NZ235316A (en) 1992-11-25
KR0180559B1 (ko) 1999-03-20
PL168587B1 (pl) 1996-03-29
DE69029396T2 (de) 1997-06-05
JPH05500455A (ja) 1993-02-04
HU219327B (en) 2001-03-28
YU176490A (sh) 1992-12-21
PT95316A (pt) 1991-06-25
CA2066221A1 (fr) 1991-03-16
CA2383393A1 (fr) 1991-04-04
DK0491865T3 (da) 1997-06-02
GR1002294B (el) 1996-05-03

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees