IL94982A - History of herpes tetrapeptide with a side chain of converted aspartic acid in their preparation and pharmaceutical preparations containing - Google Patents
History of herpes tetrapeptide with a side chain of converted aspartic acid in their preparation and pharmaceutical preparations containingInfo
- Publication number
- IL94982A IL94982A IL9498290A IL9498290A IL94982A IL 94982 A IL94982 A IL 94982A IL 9498290 A IL9498290 A IL 9498290A IL 9498290 A IL9498290 A IL 9498290A IL 94982 A IL94982 A IL 94982A
- Authority
- IL
- Israel
- Prior art keywords
- asp
- alkyl
- phenyl
- hydrogen
- peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA000605061A CA1340681C (en) | 1989-07-07 | 1989-07-07 | Antiherpes tetrapeptides having a substituted aspartic acid side chain |
CA 2019006 CA2019006C (en) | 1990-06-14 | 1990-06-14 | Antiherpes tetrapeptide derivatives having a cycloalkyl substituted aspartic acid side chain |
Publications (2)
Publication Number | Publication Date |
---|---|
IL94982A0 IL94982A0 (en) | 1991-06-10 |
IL94982A true IL94982A (en) | 1995-11-27 |
Family
ID=25672868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9498290A IL94982A (en) | 1989-07-07 | 1990-07-05 | History of herpes tetrapeptide with a side chain of converted aspartic acid in their preparation and pharmaceutical preparations containing |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0411333B1 (de) |
JP (1) | JP2879799B2 (de) |
AT (1) | ATE123294T1 (de) |
AU (1) | AU643403B2 (de) |
DE (1) | DE69019786T2 (de) |
IL (1) | IL94982A (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1340682C (en) * | 1989-07-07 | 1999-07-27 | Pierre Lavallee | Antiviral peptides having a 2-oxoalkyl amino acid side chain |
AU643636B2 (en) * | 1989-07-07 | 1993-11-18 | Bio-Mega/Boehringer Ingelheim Research Inc. | Antiherpes pentapeptide derivatives having a substituted aspartic acid side chain |
EP0560267B1 (de) | 1992-03-12 | 1998-08-19 | Boehringer Ingelheim (Canada) Ltd. | Isosterische Peptidderivate gegen Herpes |
US5846941A (en) * | 1992-03-12 | 1998-12-08 | Boehringer Ingelheim (Canada) Ltd. | Isosteric antiherpes peptide derivatives II |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4795740A (en) * | 1986-05-20 | 1989-01-03 | Cohen Eric A | Antiviral peptides and means for treating herpes infections |
EP0292255A3 (de) * | 1987-05-22 | 1990-08-22 | Merck & Co. Inc. | Hemmungsstoff für Ribonukleotid-Reduktase |
CA1327869C (en) * | 1989-02-17 | 1994-03-15 | Yvan Guindon | Ribonucleotide reductase inhibitors |
CA1340682C (en) * | 1989-07-07 | 1999-07-27 | Pierre Lavallee | Antiviral peptides having a 2-oxoalkyl amino acid side chain |
AU643636B2 (en) * | 1989-07-07 | 1993-11-18 | Bio-Mega/Boehringer Ingelheim Research Inc. | Antiherpes pentapeptide derivatives having a substituted aspartic acid side chain |
-
1990
- 1990-07-03 EP EP90112645A patent/EP0411333B1/de not_active Expired - Lifetime
- 1990-07-03 DE DE69019786T patent/DE69019786T2/de not_active Expired - Fee Related
- 1990-07-03 AT AT90112645T patent/ATE123294T1/de not_active IP Right Cessation
- 1990-07-05 IL IL9498290A patent/IL94982A/en not_active IP Right Cessation
- 1990-07-06 JP JP2179375A patent/JP2879799B2/ja not_active Expired - Lifetime
- 1990-07-06 AU AU58776/90A patent/AU643403B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JPH03215495A (ja) | 1991-09-20 |
EP0411333A1 (de) | 1991-02-06 |
JP2879799B2 (ja) | 1999-04-05 |
IL94982A0 (en) | 1991-06-10 |
EP0411333B1 (de) | 1995-05-31 |
AU643403B2 (en) | 1993-11-11 |
DE69019786T2 (de) | 1995-11-16 |
ATE123294T1 (de) | 1995-06-15 |
AU5877690A (en) | 1991-01-10 |
DE69019786D1 (de) | 1995-07-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5484771A (en) | Antiherpes peptide derivatives having a 1,4-dioxo-C, N-terminus | |
US6313095B1 (en) | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | |
EP0493770B1 (de) | Antiherpes-Zusammensetzungen | |
EP0411334B1 (de) | Pentapeptidderivate, wirksam gegen Herpes, die eine ersetzte Asparaginsäureseitenkette enthalten | |
EP0411332B1 (de) | Antivirale Peptide, die eine 2-Ketoalkylaminosäureseitenkette enthalten | |
EP0411333B1 (de) | Antiherpes-Tetrapeptid-Derivate mit einer substituierten Seitenkette aus Asparaginsäure | |
CA1340683C (en) | Antiherpes pentapeptides having a substituted aspartic acid side chain | |
EP0408973B1 (de) | Antiherpes-Pentapeptide | |
US5149778A (en) | Cyclic peptides for treating herpes infections | |
US5258493A (en) | Cyclic peptides for treating herpes infections | |
CA2019005C (en) | Antiherpes pentapeptide derivatives having a cycloalkyl substituted aspartic acid side chain | |
CA2019006C (en) | Antiherpes tetrapeptide derivatives having a cycloalkyl substituted aspartic acid side chain | |
US5648337A (en) | Antiherpes pentapeptides | |
EP0560274B1 (de) | Peptidderivate mit einem Ureido-N-Terminus gegen Herpes | |
US5830864A (en) | Antiherpes peptide derivatives having a ureido n-terminus | |
NZ234373A (en) | Acylated n-terminal tetrapeptides having an esterified or amidified aspartic acid residue and optionally substituted at the c-terminal by 5-1h-tetrazolyl; use in treatment of herpes virus infections |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
RH | Patent void |