IL94330A - תכשיר רוקחות המכיל הורמון המשחרר גונאדוטרופין - Google Patents
תכשיר רוקחות המכיל הורמון המשחרר גונאדוטרופיןInfo
- Publication number
- IL94330A IL94330A IL9433090A IL9433090A IL94330A IL 94330 A IL94330 A IL 94330A IL 9433090 A IL9433090 A IL 9433090A IL 9433090 A IL9433090 A IL 9433090A IL 94330 A IL94330 A IL 94330A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical composition
- composition according
- treatment
- disease
- symptoms
- Prior art date
Links
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- 210000003249 myenteric plexus Anatomy 0.000 description 1
- 230000003183 myoelectrical effect Effects 0.000 description 1
- BLCLNMBMMGCOAS-UHFFFAOYSA-N n-[1-[[1-[[1-[[1-[[1-[[1-[[1-[2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amin Chemical compound C1CCC(C(=O)NNC(N)=O)N1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(COC(C)(C)C)NC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 BLCLNMBMMGCOAS-UHFFFAOYSA-N 0.000 description 1
- RWHUEXWOYVBUCI-ITQXDASVSA-N nafarelin Chemical compound C([C@@H](C(=O)N[C@H](CC=1C=C2C=CC=CC2=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 RWHUEXWOYVBUCI-ITQXDASVSA-N 0.000 description 1
- 229960004309 nafarelin acetate Drugs 0.000 description 1
- 239000007922 nasal spray Substances 0.000 description 1
- 229940097496 nasal spray Drugs 0.000 description 1
- 230000008904 neural response Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000002611 ovarian Effects 0.000 description 1
- 210000003101 oviduct Anatomy 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 201000010065 polycystic ovary syndrome Diseases 0.000 description 1
- 230000000136 postovulatory effect Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 208000006155 precocious puberty Diseases 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 201000001514 prostate carcinoma Diseases 0.000 description 1
- 238000001671 psychotherapy Methods 0.000 description 1
- 210000003689 pubic bone Anatomy 0.000 description 1
- 238000009613 pulmonary function test Methods 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- -1 relaxins Substances 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 208000017443 reproductive system disease Diseases 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 210000004514 sphincter of oddi Anatomy 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229960000278 theophylline Drugs 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- VXKHXGOKWPXYNA-PGBVPBMZSA-N triptorelin Chemical group C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 VXKHXGOKWPXYNA-PGBVPBMZSA-N 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
- 210000000626 ureter Anatomy 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 230000006496 vascular abnormality Effects 0.000 description 1
- 208000019183 visceral myopathy Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/349,717 US5068221A (en) | 1989-05-09 | 1989-05-09 | Treatment of motility disorders with a gnrh analog |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL94330A0 IL94330A0 (en) | 1991-03-10 |
| IL94330A true IL94330A (he) | 1995-03-30 |
Family
ID=23373648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9433090A IL94330A (he) | 1989-05-09 | 1990-05-08 | תכשיר רוקחות המכיל הורמון המשחרר גונאדוטרופין |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5068221A (he) |
| EP (1) | EP0471761B1 (he) |
| JP (1) | JPH04505016A (he) |
| KR (1) | KR920700676A (he) |
| AT (1) | ATE110277T1 (he) |
| AU (2) | AU628763B2 (he) |
| CA (1) | CA2053880C (he) |
| DE (1) | DE69011857T2 (he) |
| DK (1) | DK0471761T3 (he) |
| ES (1) | ES2057565T3 (he) |
| IL (1) | IL94330A (he) |
| NZ (1) | NZ248242A (he) |
| WO (1) | WO1990013308A1 (he) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5434136A (en) * | 1990-12-14 | 1995-07-18 | Mathias; John R. | Treatment of motility disorders with a GNRH analog |
| US5470847A (en) * | 1993-12-10 | 1995-11-28 | Board Of Regents, The University Of Texas System | Ovulation control by regulating nitric oxide levels with arginine derivatives |
| KR100440643B1 (ko) * | 1999-01-28 | 2004-07-21 | 쥬가이 세이야쿠 가부시키가이샤 | 치환 페네틸아민 유도체 |
| CA2522690A1 (en) * | 2003-05-06 | 2004-11-25 | Syntonix Pharmaceuticals, Inc. | Inhibition of drug binding to serum albumin |
| US20200146313A1 (en) * | 2018-11-09 | 2020-05-14 | Ims Trading, Llc | Edible pet chews and methods of forming the same |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO139560C (no) * | 1972-04-29 | 1979-04-04 | Takeda Chemical Industries Ltd | Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater |
| CA1009230A (en) * | 1972-09-26 | 1977-04-26 | Daiichi Seiyaku Co. | Peptides effecting to the release of sex hormones and a method for preparing the same |
| JPS563846B2 (he) * | 1972-10-12 | 1981-01-27 | ||
| AT347054B (de) * | 1973-09-29 | 1978-12-11 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von neuen nonapeptidamid-derivaten |
| US3914412A (en) * | 1973-10-11 | 1975-10-21 | Abbott Lab | {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity |
| US4005063A (en) * | 1973-10-11 | 1977-01-25 | Abbott Laboratories | [Des-gly]10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity |
| US4072668A (en) * | 1973-11-06 | 1978-02-07 | The Salk Institute For Biological Studies | LH-RH Analogs |
| US4552764A (en) * | 1974-11-14 | 1985-11-12 | Research Corporation | Peptides for control of intestinal motility |
| US4010261A (en) * | 1974-11-25 | 1977-03-01 | Abbott Laboratories | Method to prevent reproduction with [Des-Gly]10 -GN-RH nonadeptide amide analogs in position |
| US4002738A (en) * | 1975-05-30 | 1977-01-11 | Abbott Laboratories | Treatment of specified neoplasias |
| US4005194A (en) * | 1975-06-23 | 1977-01-25 | Abbott Laboratories | Treatment of prostatic hyperplasia |
| US4018914A (en) * | 1975-11-13 | 1977-04-19 | Abbott Laboratories | Parturition inducement |
| JPS54148722A (en) * | 1978-05-12 | 1979-11-21 | Takeda Chem Ind Ltd | Nonapeptide and its preparation |
| FR2465486A1 (fr) * | 1979-09-21 | 1981-03-27 | Roussel Uclaf | Nouvelle application utilisant la lh-rh ou des agonistes |
| US4409208A (en) * | 1980-04-15 | 1983-10-11 | The Salk Institute For Biological Studies | GnRH antagonists |
| US4410514A (en) * | 1982-12-06 | 1983-10-18 | The Salk Institute For Biological Studies | GnRH Agonists |
| US4619914A (en) * | 1983-03-10 | 1986-10-28 | The Salk Institute For Biological Studies | GNRH antagonists IIIB |
| US4569927A (en) * | 1984-02-23 | 1986-02-11 | The Salk Institute For Biological Studies | GnRH Antagonists IV |
| US4652550A (en) * | 1984-05-21 | 1987-03-24 | The Salk Institute For Biological Studies | GnRH antagonists VII |
| US4565804A (en) * | 1984-09-07 | 1986-01-21 | The Salk Institute For Biological Studies | GnRH Antagonists VI |
| US4752577A (en) * | 1984-09-13 | 1988-06-21 | Eli Lilly And Company | Method for using a novel transcriptional- and translational-activating sequence in streptomyces |
| US4690916A (en) * | 1984-11-13 | 1987-09-01 | Syntex (U.S.A.) Inc. | Nona and decapeptide analogs of LHRH useful as LHRH antagonists |
| US4740500A (en) * | 1985-01-31 | 1988-04-26 | The Salk Institute For Biological Studies | GnRH antagonists VIII |
| US4725577A (en) * | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
| US4661472A (en) * | 1985-05-09 | 1987-04-28 | The Salk Institute For Biological Studies | GnRH antagonists IX |
| US4920102A (en) * | 1988-04-18 | 1990-04-24 | Eli Lilly And Company | Method for treating gastrointestinal disorders |
-
1989
- 1989-05-09 US US07/349,717 patent/US5068221A/en not_active Expired - Lifetime
-
1990
- 1990-05-03 KR KR1019910701549A patent/KR920700676A/ko not_active Abandoned
- 1990-05-03 DE DE69011857T patent/DE69011857T2/de not_active Expired - Fee Related
- 1990-05-03 CA CA002053880A patent/CA2053880C/en not_active Expired - Fee Related
- 1990-05-03 DK DK90907817.2T patent/DK0471761T3/da active
- 1990-05-03 JP JP2507135A patent/JPH04505016A/ja active Pending
- 1990-05-03 WO PCT/US1990/002455 patent/WO1990013308A1/en not_active Ceased
- 1990-05-03 ES ES90907817T patent/ES2057565T3/es not_active Expired - Lifetime
- 1990-05-03 AT AT90907817T patent/ATE110277T1/de not_active IP Right Cessation
- 1990-05-03 EP EP90907817A patent/EP0471761B1/en not_active Expired - Lifetime
- 1990-05-03 AU AU55595/90A patent/AU628763B2/en not_active Ceased
- 1990-05-07 NZ NZ248242A patent/NZ248242A/en unknown
- 1990-05-08 IL IL9433090A patent/IL94330A/he not_active IP Right Cessation
-
1992
- 1992-05-12 AU AU16203/92A patent/AU639403B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DK0471761T3 (da) | 1994-09-19 |
| ES2057565T3 (es) | 1994-10-16 |
| KR920700676A (ko) | 1992-08-10 |
| EP0471761B1 (en) | 1994-08-24 |
| CA2053880C (en) | 1997-01-14 |
| AU639403B2 (en) | 1993-07-22 |
| NZ248242A (en) | 1997-07-27 |
| AU628763B2 (en) | 1992-09-17 |
| IL94330A0 (en) | 1991-03-10 |
| EP0471761A1 (en) | 1992-02-26 |
| JPH04505016A (ja) | 1992-09-03 |
| US5068221A (en) | 1991-11-26 |
| CA2053880A1 (en) | 1990-11-10 |
| WO1990013308A1 (en) | 1990-11-15 |
| DE69011857T2 (de) | 1995-03-23 |
| AU1620392A (en) | 1992-07-30 |
| ATE110277T1 (de) | 1994-09-15 |
| DE69011857D1 (de) | 1994-09-29 |
| EP0471761A4 (en) | 1992-06-24 |
| AU5559590A (en) | 1990-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |