IL93610A0 - Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL93610A0 IL93610A0 IL93610A IL9361090A IL93610A0 IL 93610 A0 IL93610 A0 IL 93610A0 IL 93610 A IL93610 A IL 93610A IL 9361090 A IL9361090 A IL 9361090A IL 93610 A0 IL93610 A0 IL 93610A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- tetrahydroquinoline derivatives
- tetrahydroquinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Other Liquid Machine Or Engine Such As Wave Power Use (AREA)
- Hydrogenated Pyridines (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898905334A GB8905334D0 (en) | 1989-03-08 | 1989-03-08 | Therapeutic agents |
GB898926431A GB8926431D0 (en) | 1989-11-22 | 1989-11-22 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
IL93610A0 true IL93610A0 (en) | 1990-12-23 |
Family
ID=26295073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL93610A IL93610A0 (en) | 1989-03-08 | 1990-03-02 | Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0386839B1 (fr) |
JP (1) | JPH0334969A (fr) |
KR (1) | KR900014321A (fr) |
AT (1) | ATE147732T1 (fr) |
AU (1) | AU5114490A (fr) |
CA (1) | CA2011686A1 (fr) |
DE (1) | DE69029668T2 (fr) |
FI (1) | FI901148A0 (fr) |
IL (1) | IL93610A0 (fr) |
NO (1) | NO901082L (fr) |
PT (1) | PT93362A (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5268378A (en) * | 1990-05-31 | 1993-12-07 | Merck Sharp & Dohme, Limited | Dioxo-tetrahydroquinoline derivatives |
US5401848A (en) * | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
US5606063A (en) * | 1991-02-27 | 1997-02-25 | Merrell Pharmaceuticals Inc. | NMDA antagonists |
ES2089511T3 (es) * | 1991-02-27 | 1996-10-01 | Merrell Pharma Inc | Dihidroquinolina antagonistas de nmda. |
GB9109007D0 (en) * | 1991-04-26 | 1991-06-12 | Merck Sharp & Dohme | Therapeutic method |
FR2683818B1 (fr) * | 1991-11-14 | 1993-12-31 | Adir Cie | Nouveaux derives de 3-sulfonylamino-2-(1h)-quinoleinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
GB9125515D0 (en) * | 1991-11-29 | 1992-01-29 | Merck Sharp & Dohme | Therapeutic agents |
WO1997012870A1 (fr) * | 1995-09-29 | 1997-04-10 | Glaxo Wellcome S.P.A. | Tetrahydroquinolines utiles en tant qu'antagonistes du nmda (n-methyl-d-aspartate) |
GB9617305D0 (en) | 1996-08-17 | 1996-09-25 | Glaxo Wellcome Spa | Heterocyclic compounds |
DE19705133A1 (de) * | 1997-02-11 | 1998-08-13 | Hoechst Ag | Sulfonamid-substituierte Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
GB9706294D0 (en) * | 1997-03-26 | 1997-05-14 | Glaxo Wellcome Spa | Heterocyclic compound |
MY125037A (en) * | 1998-06-10 | 2006-07-31 | Glaxo Wellcome Spa | 1,2,3,4 tetrahydroquinoline derivatives |
US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
EP1607389A1 (fr) * | 1999-09-10 | 2005-12-21 | Pfizer Products Inc. | DERIVES 4-amino-1,2,3,4-tétrahydroquinoline N-protégés et 2-substitues, utiles comme intermédiaires pour des inhibiteurs CETP |
DE10000311A1 (de) | 2000-01-05 | 2001-07-12 | Gruenenthal Gmbh | Aminomethyl-Phonyl-Cyclohexanonderivate |
DE10005302A1 (de) * | 2000-02-07 | 2002-01-17 | Gruenenthal Gmbh | Substituierte 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate |
WO2002046185A1 (fr) * | 2000-12-07 | 2002-06-13 | Japan Science And Technology Corporation | Intermediaires de synthese de composes de vinblastine et leur procede de synthese |
DE10132725A1 (de) | 2001-07-05 | 2006-08-03 | Grünenthal GmbH | Substituierte γ-Lactonverbindungen |
DE10137487A1 (de) * | 2001-08-03 | 2003-03-27 | Gruenenthal Gmbh | Substituierte 5,6,6a,11b-Tetrahydro-7-oxa-6-aza- benzo[c]fluoren-6-carbonsäurederivate |
DE10137488A1 (de) * | 2001-08-03 | 2003-02-20 | Gruenenthal Gmbh | Salze substituierter 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate |
EP2527339A1 (fr) * | 2004-11-24 | 2012-11-28 | Abbott Laboratories | Composés de chromanylurée inhibant le récepteur du sous-type 1 (VR1) du récepteur de vanilloïde et leurs utilisations |
UY30244A1 (es) | 2006-03-30 | 2007-11-30 | Tanabe Seiyaku Co | Un proceso para preparar derivados de tetrahidroquinolina |
EP3427729A1 (fr) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probénécide destiné à être utilisé dans le traitement de maladies, troubles ou états épileptiques |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH23848A (en) * | 1985-05-24 | 1989-11-23 | Ciba Geigy Ag | Certain phosphonic acids and derivatives |
GB8719102D0 (en) * | 1987-08-12 | 1987-09-16 | Merck Sharp & Dohme | Therapeutic agents |
-
1990
- 1990-03-02 AT AT90200499T patent/ATE147732T1/de not_active IP Right Cessation
- 1990-03-02 IL IL93610A patent/IL93610A0/xx unknown
- 1990-03-02 DE DE69029668T patent/DE69029668T2/de not_active Expired - Fee Related
- 1990-03-02 EP EP90200499A patent/EP0386839B1/fr not_active Expired - Lifetime
- 1990-03-07 FI FI901148A patent/FI901148A0/fi not_active Application Discontinuation
- 1990-03-07 NO NO90901082A patent/NO901082L/no unknown
- 1990-03-07 AU AU51144/90A patent/AU5114490A/en not_active Abandoned
- 1990-03-07 PT PT93362A patent/PT93362A/pt not_active Application Discontinuation
- 1990-03-07 CA CA002011686A patent/CA2011686A1/fr not_active Abandoned
- 1990-03-08 JP JP2057811A patent/JPH0334969A/ja active Pending
- 1990-03-08 KR KR1019900003022A patent/KR900014321A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69029668D1 (de) | 1997-02-27 |
EP0386839B1 (fr) | 1997-01-15 |
NO901082D0 (no) | 1990-03-07 |
NO901082L (no) | 1990-09-10 |
EP0386839A3 (fr) | 1991-10-23 |
DE69029668T2 (de) | 1997-08-07 |
CA2011686A1 (fr) | 1990-09-08 |
JPH0334969A (ja) | 1991-02-14 |
PT93362A (pt) | 1990-11-07 |
EP0386839A2 (fr) | 1990-09-12 |
ATE147732T1 (de) | 1997-02-15 |
FI901148A0 (fi) | 1990-03-07 |
AU5114490A (en) | 1990-09-13 |
KR900014321A (ko) | 1990-10-23 |
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