IL93107A - Peptides that inhibit the maturation of T lymphocytes and the activity of macrophages, pharmaceutical preparations containing them, and the process for their preparation - Google Patents

Peptides that inhibit the maturation of T lymphocytes and the activity of macrophages, pharmaceutical preparations containing them, and the process for their preparation

Info

Publication number
IL93107A
IL93107A IL9310790A IL9310790A IL93107A IL 93107 A IL93107 A IL 93107A IL 9310790 A IL9310790 A IL 9310790A IL 9310790 A IL9310790 A IL 9310790A IL 93107 A IL93107 A IL 93107A
Authority
IL
Israel
Prior art keywords
lys
asp
arg
val
group
Prior art date
Application number
IL9310790A
Other languages
English (en)
Hebrew (he)
Other versions
IL93107A0 (en
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL93107A0 publication Critical patent/IL93107A0/xx
Publication of IL93107A publication Critical patent/IL93107A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL9310790A 1989-01-13 1990-01-18 Peptides that inhibit the maturation of T lymphocytes and the activity of macrophages, pharmaceutical preparations containing them, and the process for their preparation IL93107A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU89116A HU201964B (en) 1989-01-13 1989-01-13 Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same

Publications (2)

Publication Number Publication Date
IL93107A0 IL93107A0 (en) 1990-11-05
IL93107A true IL93107A (en) 1994-04-12

Family

ID=10948008

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9310790A IL93107A (en) 1989-01-13 1990-01-18 Peptides that inhibit the maturation of T lymphocytes and the activity of macrophages, pharmaceutical preparations containing them, and the process for their preparation

Country Status (12)

Country Link
US (1) US5093320A (hu)
EP (1) EP0378432B1 (hu)
JP (1) JPH02270895A (hu)
CN (1) CN1031344C (hu)
AT (1) ATE120758T1 (hu)
AU (1) AU632526B2 (hu)
CA (1) CA2008438A1 (hu)
DE (1) DE69018275T2 (hu)
DK (1) DK0378432T3 (hu)
ES (1) ES2071004T3 (hu)
HU (1) HU201964B (hu)
IL (1) IL93107A (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201964B (en) * 1989-01-13 1991-01-28 Richter Gedeon Vegyeszet Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
WO1991004746A1 (en) * 1989-09-29 1991-04-18 Rhone-Poulenc Rorer International (Holdings) Inc. Anti-thrombotic peptides and pseudopeptides
US5332726A (en) * 1989-09-29 1994-07-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Antithrombotic peptides and pseudopeptides
US6197529B1 (en) * 1990-11-21 2001-03-06 Torrey Pines Institute For Molecular Studies Linear substituted oligoalkyleneimine libraries
MX9201416A (es) * 1991-03-28 1992-10-01 Rhone Poulenc Rorer Int Peptidos y pseudopeptidos antitromboticos.
AU7392294A (en) * 1993-07-21 1995-02-20 Vladimir Khatskelevich Khavinson Pharmaceutical with immunomodulating activity
FR2788058B1 (fr) * 1998-12-30 2002-01-25 Sederma Sa Compositions cosmetiques amincissantes
KR100464787B1 (ko) * 2002-03-20 2005-01-06 박용석 글루탐산염을 이용한 양전하 지질의 제조방법
CN107021996B (zh) * 2017-05-24 2020-02-14 中国海洋大学 一种短肽、其应用以及由其得到的抗菌组合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190646A (en) * 1975-11-11 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptide compositions and methods
US4215112A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Tripeptides and methods
CA1157466A (en) * 1979-04-12 1983-11-22 Gideon Goldstein Peptides having thymopoietin-like activity
EP0033384B1 (de) * 1980-01-18 1984-02-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Thymosin-alpha-1-Fragmente enthaltende Arzneimittel mit immunstimulierender Wirkung, und Thymosin-alpha-1-Fragmente
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
US4442031A (en) * 1981-10-15 1984-04-10 Hoffmann-La Roche Inc. Immunopotentiating peptides
US4395404A (en) * 1982-05-14 1983-07-26 George Washington University Synthetic thymosin β3 and β4 analogues
DE3421614A1 (de) * 1984-06-09 1985-12-12 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von pentapeptiden mit wirkung auf das immunsystem und zwischenprodukte dieses verfahrens
WO1986004334A1 (en) * 1985-01-18 1986-07-31 MERCK Patent Gesellschaft mit beschränkter Haftung Immunoregulatory peptides
JP2646013B2 (ja) * 1988-09-14 1997-08-25 株式会社ジャパンエナジー 抗ウイルス剤
HU201964B (en) * 1989-01-13 1991-01-28 Richter Gedeon Vegyeszet Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
AU4792290A (en) 1990-09-20
CN1044102A (zh) 1990-07-25
DE69018275T2 (de) 1995-08-03
EP0378432A3 (en) 1991-04-24
HU201964B (en) 1991-01-28
DK0378432T3 (da) 1995-05-01
US5093320A (en) 1992-03-03
EP0378432B1 (en) 1995-04-05
CA2008438A1 (en) 1991-07-24
CN1031344C (zh) 1996-03-20
DE69018275D1 (de) 1995-05-11
HUT53123A (en) 1990-09-28
EP0378432A2 (en) 1990-07-18
ES2071004T3 (es) 1995-06-16
IL93107A0 (en) 1990-11-05
AU632526B2 (en) 1993-01-07
JPH02270895A (ja) 1990-11-05
ATE120758T1 (de) 1995-04-15

Similar Documents

Publication Publication Date Title
US4910296A (en) Medicaments containing alpha 1 thymosin fragments and having an immunostimulant action, and fragments of alpha 1 thymosin
US4612365A (en) Medicaments containing alpha 1-thymosin and having an immuno regulatory action and alpha 1-thymosin fragments
RU2107692C1 (ru) Пептид и способ его получения
AU602483B2 (en) Immunoregulatory peptides
US4420424A (en) New peptides and a process for their preparation
JPS5989649A (ja) 酸−プロテア−ゼ抑制ペプチド誘導体
WO1993005011A1 (en) Novel immunosuppressants
EP0378432B1 (en) Novel peptides, their use to inhibit the maturation of t-lymphocytes and the activity of macrophages, and processes for their preparation
AU620406B2 (en) Novel peptides suppressing the function of the immune system, pharmaceutical compositions containing them and process for preparing same
US4223016A (en) Peptides
CA2173939C (en) Oligopeptides derived from c-reactive protein fragments
US5041535A (en) Antileukemic and immunostimulant peptides
RU2163242C2 (ru) Циклогексапептиды, их смеси, способ их получения
US5118669A (en) Peptides and intermediates therefor useful as antiallergic agents, vasodilators and immunoregulators
PL130448B1 (en) Process for preparing novel analogs of angiotensine ii
WO1992013877A1 (en) Factor iia inhibitors
RU1124544C (ru) Гептапептид, обладающий свойствами психостимулятора пролонгированного действия с иммунотропной активность
US4637997A (en) Hexapeptide, process for obtaining II and the pharmaceutical compositions containing II
IE900850L (en) Sdk peptides, a preparation process of the same and¹therapeutic compositions containing them
JPH04221394A (ja) ペプチド脂質
JPH0940577A (ja) トリペプチド、ジペプチドを含有する医薬組成物
JPH04198194A (ja) ポリペプチドおよびその用途
JPH06239885A (ja) ペプチド誘導体及びその用途
AU3318184A (en) Immunotherapeutic polypeptide agents
HU196226B (en) Process for producing new tripeptide derivatives of antiamnesic activity and pharmaceutical compositions containing them as active components

Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void