IL92996A - Photoactive compounds as medicaments for the treatment of virus infections and method for production of vaccines - Google Patents

Photoactive compounds as medicaments for the treatment of virus infections and method for production of vaccines

Info

Publication number
IL92996A
IL92996A IL9299690A IL9299690A IL92996A IL 92996 A IL92996 A IL 92996A IL 9299690 A IL9299690 A IL 9299690A IL 9299690 A IL9299690 A IL 9299690A IL 92996 A IL92996 A IL 92996A
Authority
IL
Israel
Prior art keywords
virus
blood
compound
treatment
compound according
Prior art date
Application number
IL9299690A
Other languages
English (en)
Original Assignee
Bisaccia Emil
Klainer Albert S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/295,454 external-priority patent/US4960408A/en
Application filed by Bisaccia Emil, Klainer Albert S filed Critical Bisaccia Emil
Publication of IL92996A publication Critical patent/IL92996A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0066—Psoralene-activated UV-A photochemotherapy (PUVA-therapy), e.g. for treatment of psoriasis or eczema, extracorporeal photopheresis with psoralens or fucocoumarins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • External Artificial Organs (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL9299690A 1989-01-10 1990-01-08 Photoactive compounds as medicaments for the treatment of virus infections and method for production of vaccines IL92996A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/295,454 US4960408A (en) 1989-01-10 1989-01-10 Treatment methods and vaccines for stimulating an immunological response against retroviruses
US36406389A 1989-06-08 1989-06-08
US46081190A 1990-01-04 1990-01-04

Publications (1)

Publication Number Publication Date
IL92996A true IL92996A (en) 1996-06-18

Family

ID=27404363

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9299690A IL92996A (en) 1989-01-10 1990-01-08 Photoactive compounds as medicaments for the treatment of virus infections and method for production of vaccines

Country Status (9)

Country Link
EP (1) EP0453497A4 (de)
JP (1) JPH04502621A (de)
AU (1) AU638693B2 (de)
BR (1) BR9007016A (de)
CA (1) CA2007499C (de)
FI (1) FI105453B (de)
HU (1) HUT62487A (de)
IL (1) IL92996A (de)
WO (1) WO1990007952A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120649A (en) * 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
US6433343B1 (en) 1992-03-02 2002-08-13 Cerus Corporation Device and method for photoactivation
FR2694886A1 (fr) * 1992-08-06 1994-02-25 Zaki George Procédé et dispositif pour stériliser le sang des malades du sida, de la malaria ou d'une autre maladie bactérienne, parasitaire ou virale du sang.
FR2698270B1 (fr) * 1992-11-20 1995-01-13 Goupil Jean Jacques Utilisation du 5-méthoxypsoralène dans le traitement du sida.
AU1172195A (en) * 1993-11-10 1995-05-29 Steritech, Inc. Device and method for photoactivation
AU691672B2 (en) * 1994-09-22 1998-05-21 Baxter International Inc. Photodynamic inactivation of viral and bacterial blood contaminants with halogenated coumarin and furocoumarin sensitizers
DE19914850A1 (de) * 1999-04-01 2000-10-05 Gerhard Saalmann Vorrichtung und Verfahren zur Inaktivierung von Viren in biologischen Flüssigkeiten
AU2002332697A1 (en) * 2001-12-12 2003-06-23 Leon J. Lewandowski Photophoretic auto immune stimulation
WO2004084936A2 (en) * 2003-02-06 2004-10-07 Cerus Corporation Modified free-living microbes, vaccine compositions and methods of use thereof
WO2008036285A1 (en) * 2006-09-18 2008-03-27 Energex Systems, Inc. Method of treating viral infections with ultraviolet light
GB2509940A (en) * 2013-01-18 2014-07-23 John Ogino Vaccine production via irradiation of pathogenic cultures

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321919A (en) * 1979-12-11 1982-03-30 Leukocyte Research, Inc. Method and system for externally treating human blood
US4568542A (en) * 1981-06-09 1986-02-04 Lee Biomolecular Research Laboratories, Inc. Vaccine compositions
US4464166A (en) * 1981-06-12 1984-08-07 Frederic A. Bourke, Jr. Method for externally treating the blood
DE3483751D1 (de) * 1983-05-02 1991-01-31 Diamond Scient Co Photochemische entkeimungsbehandlung von vollem blut oder blutbestandteilen.
DK507185A (da) * 1984-11-05 1986-05-06 Du Pont Fremgangsmaade til inaktivering af human tumor leukaemi virus iii
US4838852A (en) * 1987-03-27 1989-06-13 Therakos, Inc. Active specific immune suppression

Also Published As

Publication number Publication date
CA2007499A1 (en) 1990-07-10
FI913318A0 (fi) 1991-07-09
EP0453497A1 (de) 1991-10-30
CA2007499C (en) 2001-03-27
HUT62487A (en) 1993-05-28
WO1990007952A1 (en) 1990-07-26
AU4954590A (en) 1990-08-13
JPH04502621A (ja) 1992-05-14
EP0453497A4 (en) 1992-10-07
BR9007016A (pt) 1991-11-12
FI105453B (fi) 2000-08-31
AU638693B2 (en) 1993-07-08

Similar Documents

Publication Publication Date Title
US4960408A (en) Treatment methods and vaccines for stimulating an immunological response against retroviruses
Salk Prospects for the control of AIDS by immunizing seropositive individuals
DE69734450T2 (de) Photopherese-behandlung von hcv-infektionen
AU638693B2 (en) Treatment methods and vaccines
JP5037775B2 (ja) 抗ウイルス薬および癌に対する医薬の製造のためのパラポックスウイルスｏｖｉｓの使用
QUINNAN Jr et al. Mechanisms of T-cell functional deficiency in the acquired immunodeficiency syndrome
EP0101200A2 (de) Transferfaktor zur Anwendung in der Behandlung von Virusinfektionen
CA1095407A (en) Preparation for the treatment of herpes zoster and other herpes infections, as well as method for manufacture thereof
Sutherland et al. CD4 and CD8 T cells are not major effectors of mouse hepatitis virus A59-induced demyelinating disease
WO1989005657A1 (en) Lymphokine activation of cells for adoptive immunotherapy, e.g. of hiv infection
EP1438970B1 (de) Methoden zur Inhibition von HIV-assoziierten Krankheiten mittels monoklonaler Antikörper gegen sich selbstgerichtete zytotoxische T-Zellen
Viza et al. Specific transfer factor protects mice against lethal challenge with herpes simplex virus
US7439052B2 (en) Method of making modified immunodeficiency virus particles
US20030035813A1 (en) Immunological treatment methods and agents
US6471965B1 (en) Vaccine containing whole killed herpes viruses to prevent development of atherosclerotic plaque
Gonzalez et al. Cytolytic response to HIV in patients with HIV disease treated with extracorporeal photochemotherapy: preliminary study
JP2012121902A (ja) 抗ウイルス薬および癌に対する医薬を製造するためのパラポックスウイルスｏｖｉｓ株の使用
Grandgeorge et al. Inactivation of the human immunodeficiency viruses (HIV‐1 and HIV‐2) during the manufacturing of placental albumin and gammaglobulins
WO1996030045A1 (en) Vaccine for the immunoprophylaxis of the infection from feline immunodeficiency virus in the domestic cat
JP3007127B2 (ja) Ｈｓｖ経口ワクチン及びその製造方法
TOOMEY et al. Attempts to produce absorption of poliomyelitis virus by peripheral nerves in vitro
Oie et al. Studies on reovirus type 2: viral interference with UV-inactived virus
AU2008201523A1 (en) Modified viral particles with immunogenic properties and reduced lipid content useful for treating and preventing infectious diseases
McEntee et al. Comparison of the effects of 3'-azidothymidine with those of neutralizing antibodies on simian immunodeficiency virus infection in macrophages
MXPA98008019A (en) Treatment for photoferesis of chronic infections for hepatiti viruses

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH Patent void
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees