IL92986A - תולדות של טטרלין, תהליך להכנתן ותכשירי רוקחות המכילים אותן - Google Patents
תולדות של טטרלין, תהליך להכנתן ותכשירי רוקחות המכילים אותןInfo
- Publication number
- IL92986A IL92986A IL9298690A IL9298690A IL92986A IL 92986 A IL92986 A IL 92986A IL 9298690 A IL9298690 A IL 9298690A IL 9298690 A IL9298690 A IL 9298690A IL 92986 A IL92986 A IL 92986A
- Authority
- IL
- Israel
- Prior art keywords
- amino
- compounds
- compound
- mixture
- title compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/60—Naphthoxazoles; Hydrogenated naphthoxazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/04—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
- C07C225/08—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
- C07C225/12—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings with doubly-bound oxygen atoms bound to carbon atoms being part of rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/01—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to acyclic carbon atoms
- C07C205/03—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C205/04—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/28—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
- C07C205/31—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/32—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to acyclic carbon atoms and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/41—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
- C07C2602/28—Hydrogenated naphthalenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP89400056A EP0381902A1 (en) | 1989-01-09 | 1989-01-09 | Tetralin derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IL92986A0 IL92986A0 (en) | 1990-09-17 |
IL92986A true IL92986A (he) | 1994-05-30 |
Family
ID=8202914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9298690A IL92986A (he) | 1989-01-09 | 1990-01-05 | תולדות של טטרלין, תהליך להכנתן ותכשירי רוקחות המכילים אותן |
Country Status (21)
Country | Link |
---|---|
US (1) | US5041673A (he) |
EP (2) | EP0381902A1 (he) |
JP (1) | JP2761955B2 (he) |
KR (1) | KR0177805B1 (he) |
CN (1) | CN1022319C (he) |
AR (1) | AR247722A1 (he) |
AT (1) | ATE94533T1 (he) |
AU (1) | AU620676B2 (he) |
CA (1) | CA2007261C (he) |
DE (1) | DE69003257T2 (he) |
DK (1) | DK0378456T3 (he) |
ES (1) | ES2060076T3 (he) |
FI (1) | FI100799B (he) |
HU (1) | HU212494B (he) |
IE (1) | IE62997B1 (he) |
IL (1) | IL92986A (he) |
NO (1) | NO171722C (he) |
NZ (1) | NZ232031A (he) |
PH (1) | PH27288A (he) |
PT (1) | PT92808B (he) |
ZA (1) | ZA9034B (he) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5071875A (en) * | 1989-09-25 | 1991-12-10 | Northwestern University | Substituted 2-amidotetralins as melatonin agonists and antagonists |
GB9509156D0 (en) | 1995-05-05 | 1995-06-28 | Sandoz Ltd | Organic compounds |
US6844368B1 (en) | 1998-12-22 | 2005-01-18 | Edward Roberts | Compounds useful in pain management |
WO2000037426A1 (en) * | 1998-12-22 | 2000-06-29 | Astrazeneca Ab | Novel oxo-aminotetralin compounds useful in pain management |
PL207809B1 (pl) | 2003-11-20 | 2011-02-28 | Invento Społka Z Ograniczoną Odpowiedzialnością | Preforma pojemnika z tworzywa sztucznego, zwłaszcza do środków spożywczych |
CN102631664B (zh) * | 2011-01-28 | 2014-10-01 | 上海来益生物药物研究开发中心有限责任公司 | 3-氨基-2-羟基-4-苯基-缬氨酰-异亮氨酸的应用 |
JP7320113B2 (ja) * | 2019-08-23 | 2023-08-02 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
WO2021039023A1 (ja) * | 2019-08-23 | 2021-03-04 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
CN112275147B (zh) * | 2020-09-01 | 2021-08-13 | 中国科学院山西煤炭化学研究所 | 一种自聚微孔聚酰亚胺气体分离膜及其制备方法和应用 |
WO2023154896A2 (en) * | 2022-02-11 | 2023-08-17 | Adarx Pharmaceuticals, Inc. | Trkb ligand conjugated compounds and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4267373A (en) * | 1972-07-03 | 1981-05-12 | E. R. Squibb & Sons, Inc. | 5,6,7,8-Tetrahydronaphthalene hypotensive agents |
JPS561305B2 (he) * | 1972-12-18 | 1981-01-13 | ||
US3993677A (en) * | 1975-11-03 | 1976-11-23 | American Cyanamid Company | 1,2,3,4-Tetrahydro-4-oxo-1-naphthylisocyanate |
US4049717A (en) * | 1976-05-13 | 1977-09-20 | American Cyanamid Company | Novel 1,2,3,4-tetrahydro-4-oxo-(oxy)-1-naphthylamines and method of preparation thereof |
US4041070A (en) * | 1976-07-14 | 1977-08-09 | American Cyanamid Company | Tetrahydro-4-imino-1-naphthylureas |
US4051183A (en) * | 1976-09-02 | 1977-09-27 | American Cyanamid Company | 1-benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)-urea, a novel and useful intermediate for the preparation of animal growth promoting agents |
JPS6045179B2 (ja) * | 1977-06-08 | 1985-10-08 | フナイ薬品工業株式会社 | 新規環状アミノアルコ−ル類およびその製造法 |
-
1989
- 1989-01-09 EP EP89400056A patent/EP0381902A1/en not_active Withdrawn
-
1990
- 1990-01-03 ZA ZA9034A patent/ZA9034B/xx unknown
- 1990-01-04 US US07/460,693 patent/US5041673A/en not_active Expired - Fee Related
- 1990-01-05 NZ NZ232031A patent/NZ232031A/en unknown
- 1990-01-05 CA CA002007261A patent/CA2007261C/en not_active Expired - Fee Related
- 1990-01-05 ES ES90400031T patent/ES2060076T3/es not_active Expired - Lifetime
- 1990-01-05 DK DK90400031.2T patent/DK0378456T3/da active
- 1990-01-05 IL IL9298690A patent/IL92986A/he not_active IP Right Cessation
- 1990-01-05 DE DE90400031T patent/DE69003257T2/de not_active Expired - Fee Related
- 1990-01-05 EP EP90400031A patent/EP0378456B1/en not_active Expired - Lifetime
- 1990-01-05 AT AT90400031T patent/ATE94533T1/de not_active IP Right Cessation
- 1990-01-08 HU HU9068A patent/HU212494B/hu not_active IP Right Cessation
- 1990-01-08 IE IE6790A patent/IE62997B1/en not_active IP Right Cessation
- 1990-01-08 KR KR1019900000190A patent/KR0177805B1/ko not_active IP Right Cessation
- 1990-01-08 FI FI900083A patent/FI100799B/fi not_active IP Right Cessation
- 1990-01-08 PT PT92808A patent/PT92808B/pt not_active IP Right Cessation
- 1990-01-08 AR AR90315899A patent/AR247722A1/es active
- 1990-01-08 NO NO900074A patent/NO171722C/no unknown
- 1990-01-09 AU AU47827/90A patent/AU620676B2/en not_active Ceased
- 1990-01-09 JP JP2001124A patent/JP2761955B2/ja not_active Expired - Lifetime
- 1990-01-09 PH PH39864A patent/PH27288A/en unknown
- 1990-01-09 CN CN90100092A patent/CN1022319C/zh not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
RH | Patent void | ||
HC | Change of name of proprietor(s) |
Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC. |