IL92867A0 - N-pyridinyl-9h-carbazol-9-amines,a process for their preparation and their use as medicaments - Google Patents

N-pyridinyl-9h-carbazol-9-amines,a process for their preparation and their use as medicaments

Info

Publication number
IL92867A0
IL92867A0 IL92867A IL9286789A IL92867A0 IL 92867 A0 IL92867 A0 IL 92867A0 IL 92867 A IL92867 A IL 92867A IL 9286789 A IL9286789 A IL 9286789A IL 92867 A0 IL92867 A0 IL 92867A0
Authority
IL
Israel
Prior art keywords
loweralkyl
hydrogen
halogen
medicaments
preparation
Prior art date
Application number
IL92867A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL92867A0 publication Critical patent/IL92867A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
IL92867A 1988-12-27 1989-12-25 N-pyridinyl-9h-carbazol-9-amines,a process for their preparation and their use as medicaments IL92867A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/289,887 US4868190A (en) 1988-12-27 1988-12-27 N-pyridinyl-9H-carbazol-9-amines

Publications (1)

Publication Number Publication Date
IL92867A0 true IL92867A0 (en) 1990-09-17

Family

ID=23113557

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92867A IL92867A0 (en) 1988-12-27 1989-12-25 N-pyridinyl-9h-carbazol-9-amines,a process for their preparation and their use as medicaments

Country Status (19)

Country Link
US (1) US4868190A (fr)
EP (1) EP0376155B1 (fr)
JP (1) JPH0725749B2 (fr)
KR (1) KR900009596A (fr)
AT (1) ATE79118T1 (fr)
AU (1) AU623205B2 (fr)
CA (1) CA2006529C (fr)
DE (1) DE68902386T2 (fr)
DK (1) DK662189A (fr)
ES (1) ES2044043T3 (fr)
FI (1) FI896243A0 (fr)
GR (1) GR3006140T3 (fr)
IE (1) IE894175L (fr)
IL (1) IL92867A0 (fr)
NO (1) NO895222L (fr)
NZ (1) NZ231943A (fr)
PH (1) PH27122A (fr)
PT (1) PT92696A (fr)
ZA (1) ZA899904B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
US5179099A (en) * 1989-08-02 1993-01-12 Hoechst-Roussel Pharmaceuticals Incorporated 2,3-dihydro-1-(pyridinylamino)-indoles
ATE118002T1 (de) * 1989-08-02 1995-02-15 Hoechst Roussel Pharma 2,3-dihydro-1-(pyridinylamino)-indole, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.
US4994472A (en) * 1989-08-02 1991-02-19 Hoechst-Roussel Pharmaceuticals Incorporated 1-(pyridinylamino)-2-pyrrolidinones as pain relievers
US4983608A (en) * 1989-09-05 1991-01-08 Hoechst-Roussell Pharmaceuticals, Inc. N-substituted-4-pyrimidinamines and pyrimidinediamines
US5776955A (en) * 1995-07-27 1998-07-07 Hoechst Marion Roussel, Inc. Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents
CN1184969C (zh) * 1995-07-27 2005-01-19 阿温蒂斯药物公司 未取代和取代的n－(吡咯－1－基)吡啶胺作为抗惊厥药的用途
ZA989365B (en) * 1997-10-15 1999-04-15 Boehringer Mannheim Pharm Corp Preparation for treating alzheimer's disease
UA74195C2 (uk) * 2000-07-21 2005-11-15 Орто-Макнейл Фармацевтикал, Інк. Застосування карбаматної сполуки, призначеної для попередження або лікування невропатичного болю та, асоційованих з головним болем, кластерного болю і мігрені

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7181M (fr) * 1966-11-16 1969-08-11
EP0073849A1 (fr) * 1981-09-03 1983-03-16 Schering Corporation Phényltétrahydro-1,2,3,4 carbazoles, leur préparation et compositions pharmaceutiques les contenant
US4792562A (en) * 1985-12-04 1988-12-20 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing activity
US4752610A (en) * 1985-12-04 1988-06-21 Hoechst-Roussel Pharmaceuticals Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing properties
ATE115143T1 (de) * 1987-04-24 1994-12-15 Hoechst Roussel Pharma N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel.
US4806554A (en) * 1988-01-11 1989-02-21 Hoechst-Roussel Pharmaceuticals, Inc. Pyrazol and indazolpyridinamines
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
ATE118002T1 (de) * 1989-08-02 1995-02-15 Hoechst Roussel Pharma 2,3-dihydro-1-(pyridinylamino)-indole, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones

Also Published As

Publication number Publication date
NO895222L (no) 1990-06-28
DK662189D0 (da) 1989-12-22
FI896243A0 (fi) 1989-12-22
EP0376155A1 (fr) 1990-07-04
CA2006529A1 (fr) 1990-06-27
ZA899904B (en) 1991-02-27
US4868190A (en) 1989-09-19
PH27122A (en) 1993-03-16
AU623205B2 (en) 1992-05-07
CA2006529C (fr) 1999-08-10
KR900009596A (ko) 1990-07-05
DE68902386T2 (de) 1993-02-11
EP0376155B1 (fr) 1992-08-05
IE894175L (en) 1990-06-27
JPH0725749B2 (ja) 1995-03-22
JPH02247173A (ja) 1990-10-02
ATE79118T1 (de) 1992-08-15
ES2044043T3 (es) 1994-01-01
DE68902386D1 (de) 1992-09-10
NZ231943A (en) 1992-06-25
DK662189A (da) 1990-06-28
AU4720389A (en) 1990-07-05
GR3006140T3 (fr) 1993-06-21
NO895222D0 (no) 1989-12-22
PT92696A (pt) 1990-06-29

Similar Documents

Publication Publication Date Title
EP0417584A3 (en) N-substituted-4-pyrimidinamines and -pyrimidindiamines, a process for their preparation and their use as medicaments
PH25571A (en) Alpha'-alkyl-4-amino-3-quinolinemethanols, 1-(4-aralkylamino-3-quinolinyl) alaknones, their use as medicaments
IL95807A0 (en) N-aminocarbonates related to physostigmine,a process for their preparation and their use in pharmaceutical compositions
IE894175L (en) N-pyridinyl-9h-carbazol-9-amines, a process for their¹preparation and their use as medicaments
HU895830D0 (en) Process for the preparation of 1,2,3,4-tetrahydro-1,9-acridine-diamines and pharmaceutical compositions containing said compounds
AU625221B2 (en) (1,2,3,4-tetrahydro-9-acridinimino)cyclohexae carboxylic acid and related compounds, a process for their preparation and their use as medicaments
ZA904442B (en) 4,5,5a,6-tetrahydro-3h-isoxazolo(5,4,3-kl)acridines derivatives,a process for their preparation and their use as medicaments