IL92826A - Chemical process for preparing antibiotic L17392 (deglucoteicoplanin) and its salts - Google Patents
Chemical process for preparing antibiotic L17392 (deglucoteicoplanin) and its saltsInfo
- Publication number
- IL92826A IL92826A IL9282689A IL9282689A IL92826A IL 92826 A IL92826 A IL 92826A IL 9282689 A IL9282689 A IL 9282689A IL 9282689 A IL9282689 A IL 9282689A IL 92826 A IL92826 A IL 92826A
- Authority
- IL
- Israel
- Prior art keywords
- deglucoteicoplanin
- salts
- chemical process
- preparing antibiotic
- teicoplanin
- Prior art date
Links
- 238000001311 chemical methods and process Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 title abstract 2
- DKVBOUDTNWVDEP-ZCVCDMNQSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)C2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-ZCVCDMNQSA-N 0.000 title abstract 2
- 108010053950 Teicoplanin Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 229960001608 teicoplanin Drugs 0.000 abstract 1
- -1 teicoplanin compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Materials For Medical Uses (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88121707 | 1988-12-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL92826A0 IL92826A0 (en) | 1990-09-17 |
| IL92826A true IL92826A (en) | 1994-06-24 |
Family
ID=8199721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9282689A IL92826A (en) | 1988-12-27 | 1989-12-20 | Chemical process for preparing antibiotic L17392 (deglucoteicoplanin) and its salts |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5594102A (ja) |
| EP (1) | EP0376042B1 (ja) |
| JP (1) | JPH02221297A (ja) |
| KR (1) | KR900009652A (ja) |
| AT (1) | ATE135369T1 (ja) |
| CA (1) | CA2006381A1 (ja) |
| DE (1) | DE68925951T2 (ja) |
| DK (1) | DK640589A (ja) |
| ES (1) | ES2084595T3 (ja) |
| HU (1) | HU209314B (ja) |
| IL (1) | IL92826A (ja) |
| ZA (1) | ZA899773B (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8621912D0 (en) * | 1986-09-11 | 1986-10-15 | Lepetit Spa | Increasing ratio of components of anti-biotic complex |
| KR20000010589A (ko) | 1996-04-23 | 2000-02-15 | 클라우디오 쿼르타 | 항생제a40926의아미드유도체의개선된화학적제조방법 |
| CN101273272B (zh) * | 2005-09-29 | 2012-11-07 | 霍夫曼-拉罗奇有限公司 | 维生素d化合物的释放试剂 |
| EP2572204B1 (en) | 2010-05-20 | 2017-12-27 | Roche Diagnostics GmbH | Release reagent for vitamin d compounds |
| EP3467510B1 (en) | 2011-11-18 | 2022-10-26 | F. Hoffmann-La Roche AG | Release reagent for vitamin d compounds |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1496386A (en) * | 1975-03-05 | 1977-12-30 | Lepetit Spa | Antibiotics |
| US4604239A (en) * | 1982-03-24 | 1986-08-05 | Eli Lilly And Company | Antibiotics |
| GB8307847D0 (en) * | 1983-03-22 | 1983-04-27 | Lepetit Spa | Antibiotics l 17054 and l 17046 |
| US4521335A (en) * | 1983-07-13 | 1985-06-04 | Smithkline Beckman Corporation | Aglycone and pseudo-aglycones of the AAD 216 antibiotics |
| AU579120B2 (en) * | 1983-12-16 | 1988-11-17 | Gruppo Lepetit S.P.A. | Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts |
| IT1173329B (it) * | 1984-02-21 | 1987-06-24 | Lepetit Spa | Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3 |
| GB8415093D0 (en) * | 1984-06-13 | 1984-07-18 | Lepetit Spa | Antibiotic l 17392 |
| GB8420405D0 (en) * | 1984-08-10 | 1984-09-12 | Lepetit Spa | Preparing antibiotic l 17046 |
| GB8531846D0 (en) * | 1985-12-30 | 1986-02-05 | Lepetit Spa | Antibiotic a 40926 mannosyl aglycon |
| GB8608809D0 (en) * | 1986-04-11 | 1986-05-14 | Lepetit Spa | Antibiotic |
| US4742045A (en) * | 1986-07-30 | 1988-05-03 | Smithkline Beckman Corporation | Glycopeptide antibiotics |
| EP0255299A3 (en) * | 1986-07-30 | 1988-07-20 | Smithkline Beecham Corporation | Glycopeptide antibiotics |
| GB8715735D0 (en) * | 1987-07-03 | 1987-08-12 | Lepetit Spa | De-mannosyl teicoplanin derivatives |
| GB8720980D0 (en) * | 1987-09-07 | 1987-10-14 | Lepetit Spa | Derivatives |
-
1989
- 1989-12-12 EP EP89122875A patent/EP0376042B1/en not_active Expired - Lifetime
- 1989-12-12 AT AT89122875T patent/ATE135369T1/de not_active IP Right Cessation
- 1989-12-12 ES ES89122875T patent/ES2084595T3/es not_active Expired - Lifetime
- 1989-12-12 DE DE68925951T patent/DE68925951T2/de not_active Expired - Fee Related
- 1989-12-18 DK DK640589A patent/DK640589A/da not_active Application Discontinuation
- 1989-12-20 ZA ZA899773A patent/ZA899773B/xx unknown
- 1989-12-20 IL IL9282689A patent/IL92826A/xx unknown
- 1989-12-21 CA CA002006381A patent/CA2006381A1/en not_active Abandoned
- 1989-12-22 HU HU896773A patent/HU209314B/hu not_active IP Right Cessation
- 1989-12-26 KR KR1019890019475A patent/KR900009652A/ko not_active Withdrawn
- 1989-12-27 JP JP1336812A patent/JPH02221297A/ja active Pending
-
1995
- 1995-05-30 US US08/453,114 patent/US5594102A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5594102A (en) | 1997-01-14 |
| ES2084595T3 (es) | 1996-05-16 |
| HU209314B (en) | 1994-04-28 |
| KR900009652A (ko) | 1990-07-05 |
| EP0376042A1 (en) | 1990-07-04 |
| DE68925951T2 (de) | 1996-07-25 |
| CA2006381A1 (en) | 1990-06-27 |
| HUT53377A (en) | 1990-10-28 |
| JPH02221297A (ja) | 1990-09-04 |
| EP0376042B1 (en) | 1996-03-13 |
| HU896773D0 (en) | 1990-03-28 |
| DE68925951D1 (de) | 1996-04-18 |
| ZA899773B (en) | 1991-02-27 |
| ATE135369T1 (de) | 1996-03-15 |
| DK640589A (da) | 1990-06-28 |
| IL92826A0 (en) | 1990-09-17 |
| DK640589D0 (da) | 1989-12-18 |
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