IL92586A - History of 5-hydroxy and 5-methoxy-2-aminopyrimidines as inhibitors of interleukin-1 formation - Google Patents

History of 5-hydroxy and 5-methoxy-2-aminopyrimidines as inhibitors of interleukin-1 formation

Info

Publication number
IL92586A
IL92586A IL9258689A IL9258689A IL92586A IL 92586 A IL92586 A IL 92586A IL 9258689 A IL9258689 A IL 9258689A IL 9258689 A IL9258689 A IL 9258689A IL 92586 A IL92586 A IL 92586A
Authority
IL
Israel
Prior art keywords
compound
pharmaceutically
acceptable salt
interleukin
mammal
Prior art date
Application number
IL9258689A
Other languages
English (en)
Hebrew (he)
Other versions
IL92586A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL92586A0 publication Critical patent/IL92586A0/xx
Publication of IL92586A publication Critical patent/IL92586A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
IL9258689A 1988-12-14 1989-12-07 History of 5-hydroxy and 5-methoxy-2-aminopyrimidines as inhibitors of interleukin-1 formation IL92586A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28450588A 1988-12-14 1988-12-14

Publications (2)

Publication Number Publication Date
IL92586A0 IL92586A0 (en) 1990-08-31
IL92586A true IL92586A (en) 1994-06-24

Family

ID=23090453

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9258689A IL92586A (en) 1988-12-14 1989-12-07 History of 5-hydroxy and 5-methoxy-2-aminopyrimidines as inhibitors of interleukin-1 formation

Country Status (13)

Country Link
EP (1) EP0373827B1 (fr)
JP (1) JPH0651622B2 (fr)
KR (1) KR920003578B1 (fr)
AT (1) ATE96321T1 (fr)
AU (1) AU605702B2 (fr)
CA (1) CA2005196A1 (fr)
DE (1) DE68910288T2 (fr)
HU (1) HU206182B (fr)
IE (1) IE893978L (fr)
IL (1) IL92586A (fr)
PH (1) PH27120A (fr)
PT (1) PT92551A (fr)
ZA (1) ZA899508B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356898A (en) * 1991-01-31 1994-10-18 Warner-Lambert Company Substituted 4,6-di-tertiary-butyl 5-hydroxy-pyrimidines
US5248682A (en) * 1991-01-31 1993-09-28 Warner-Lambert Company 2-substituted-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
US5177079A (en) * 1991-01-31 1993-01-05 Warner-Lambert Company 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
US5270319A (en) * 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
DE102004054080A1 (de) * 2004-11-09 2006-05-11 Wella Ag Haut- oder Haarbehandlungsmittel mit Schutzeffekt

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670536B2 (de) * 1966-11-09 1975-05-28 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Neue 2-Anilino-5-acylamino-pyrimidlne
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
US4711888A (en) * 1985-07-24 1987-12-08 Pfizer Inc. Hydroxy and alkoxy pyrimidines

Also Published As

Publication number Publication date
ZA899508B (en) 1991-07-31
KR920003578B1 (ko) 1992-05-04
HU206182B (en) 1992-09-28
EP0373827A3 (fr) 1991-11-06
KR900009078A (ko) 1990-07-02
JPH0651622B2 (ja) 1994-07-06
EP0373827B1 (fr) 1993-10-27
DE68910288T2 (de) 1994-02-17
DE68910288D1 (de) 1993-12-02
JPH02218613A (ja) 1990-08-31
IL92586A0 (en) 1990-08-31
PH27120A (en) 1993-03-16
CA2005196A1 (fr) 1990-06-14
IE893978L (en) 1990-06-14
AU4613089A (en) 1990-07-19
HUT51897A (en) 1990-06-28
PT92551A (pt) 1990-06-29
EP0373827A2 (fr) 1990-06-20
ATE96321T1 (de) 1993-11-15
AU605702B2 (en) 1991-01-17

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Legal Events

Date Code Title Description
RH Patent void