IL92326A0 - Substituted oxadiamino-butanes,their preparation and pharmaceutical compositions containing them - Google Patents

Substituted oxadiamino-butanes,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL92326A0
IL92326A0 IL92326A IL9232689A IL92326A0 IL 92326 A0 IL92326 A0 IL 92326A0 IL 92326 A IL92326 A IL 92326A IL 9232689 A IL9232689 A IL 9232689A IL 92326 A0 IL92326 A0 IL 92326A0
Authority
IL
Israel
Prior art keywords
oxadiamino
butanes
substituted
preparation
pharmaceutical compositions
Prior art date
Application number
IL92326A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL92326A0 publication Critical patent/IL92326A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/04—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/63—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C255/64—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
IL92326A 1988-11-18 1989-11-16 Substituted oxadiamino-butanes,their preparation and pharmaceutical compositions containing them IL92326A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH427688 1988-11-18

Publications (1)

Publication Number Publication Date
IL92326A0 true IL92326A0 (en) 1990-07-26

Family

ID=4273087

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92326A IL92326A0 (en) 1988-11-18 1989-11-16 Substituted oxadiamino-butanes,their preparation and pharmaceutical compositions containing them

Country Status (12)

Country Link
EP (1) EP0369944A1 (da)
JP (1) JPH02188563A (da)
KR (1) KR900007409A (da)
AU (1) AU4471189A (da)
CA (1) CA2003091A1 (da)
DK (1) DK578389A (da)
FI (1) FI895446A0 (da)
HU (1) HUT51598A (da)
IL (1) IL92326A0 (da)
NO (1) NO894589L (da)
PT (1) PT92324A (da)
ZA (1) ZA898779B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU207988B (en) * 1988-10-20 1993-07-28 Biorex Kutato Fejlesztoe Kft Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
EP0452264A1 (de) * 1990-04-11 1991-10-16 Ciba-Geigy Ag Hydroxylamin-Verbindungen
EP0495750A3 (en) * 1991-01-14 1992-09-16 Ciba-Geigy Ag Heterocyclic hydroxylamine
TW214545B (da) * 1992-02-17 1993-10-11 Ciba Geigy Ag
DE4306392A1 (de) * 1993-03-02 1994-09-08 Basf Ag ß-Hydroxyoximether und bei Raumtemperatur mit ß-Hydroxyoximethern vernetzbare Dispersionen oder Lösungen
HUT72751A (en) * 1993-04-13 1996-05-28 Ciba Geigy Ag Ornithine decarboxilase inhibiting branched aminooxi amino alkane derivatives and pharmaceutical compns. contg. them
ES2100060T3 (es) * 1993-04-13 1997-06-01 Ciba Geigy Ag Aminooxi-compuestos ciclicos inhibidores de ornitina descarboxilasa.
HU218480B (hu) * 1995-06-15 2000-09-28 BIOREX Kutató és Fejlesztő Rt. Hidroxilaminszármazékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények
BR0306778A (pt) 2002-01-11 2004-12-28 Biorex Kutato Fejlesztoe Kft Derivados de carboxamidina e seu uso no tratamento de doenças vasculares

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2651083A1 (de) * 1976-11-09 1978-05-18 Hoechst Ag Neue o-alkylierte hydroxylamine, verfahren zu ihrer herstellung und ihre verwendung
FR2539413A1 (fr) * 1983-01-17 1984-07-20 Pos Lab Carbostyriloximinopropanolamines utiles comme medicaments et procede pour leur preparation
EP0184112B1 (en) * 1984-11-27 1990-05-09 Chugai Seiyaku Kabushiki Kaisha Novel vitamin d derivatives and process for producing the same
US4707498A (en) * 1986-01-14 1987-11-17 Merrell Dow Pharmaceuticals Inc. Fluorinated diaminoalkyne derivatives
ZA882719B (en) * 1987-04-23 1988-10-17 Merrell Dow Pharmaceuticals Inc. Use of odc inhibitors,dacarbazine,and interferon in the treatment of malignant melanoma

Also Published As

Publication number Publication date
DK578389D0 (da) 1989-11-17
DK578389A (da) 1990-05-19
NO894589L (no) 1990-05-21
PT92324A (pt) 1990-05-31
NO894589D0 (no) 1989-11-17
FI895446A0 (fi) 1989-11-15
HUT51598A (en) 1990-05-28
ZA898779B (en) 1990-07-25
CA2003091A1 (en) 1990-05-18
HU895959D0 (en) 1990-02-28
EP0369944A1 (de) 1990-05-23
KR900007409A (ko) 1990-06-01
AU4471189A (en) 1990-05-24
JPH02188563A (ja) 1990-07-24

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