IL90514A - A fusion gene that contains a gene for multidrug resistance that is fused to a gene for adenine diamines - Google Patents
A fusion gene that contains a gene for multidrug resistance that is fused to a gene for adenine diaminesInfo
- Publication number
- IL90514A IL90514A IL9051489A IL9051489A IL90514A IL 90514 A IL90514 A IL 90514A IL 9051489 A IL9051489 A IL 9051489A IL 9051489 A IL9051489 A IL 9051489A IL 90514 A IL90514 A IL 90514A
- Authority
- IL
- Israel
- Prior art keywords
- gene
- ada
- fusion
- cells
- fusion gene
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20278388A | 1988-06-03 | 1988-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL90514A true IL90514A (en) | 1995-10-31 |
Family
ID=22751243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9051489A IL90514A (en) | 1988-06-03 | 1989-06-02 | A fusion gene that contains a gene for multidrug resistance that is fused to a gene for adenine diamines |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0420911B1 (fr) |
JP (1) | JP2949440B2 (fr) |
AT (1) | ATE142269T1 (fr) |
AU (1) | AU634162B2 (fr) |
CA (1) | CA1339654C (fr) |
DE (1) | DE68927104T2 (fr) |
IL (1) | IL90514A (fr) |
WO (1) | WO1989012109A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990004632A1 (fr) * | 1988-10-21 | 1990-05-03 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Animaux transgeniques pour tester la resistance a de multiples medicaments |
US5756353A (en) * | 1991-12-17 | 1998-05-26 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol-and liposome-based delivery |
US6627615B1 (en) | 1991-12-17 | 2003-09-30 | The Regents Of The University Of California | Methods and compositions for in vivo gene therapy |
US5858784A (en) * | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
IL105914A0 (en) * | 1992-06-04 | 1993-10-20 | Univ California | Methods and compositions for in vivo gene therapy |
US6806084B1 (en) | 1992-06-04 | 2004-10-19 | The Regents Of The University Of California | Methods for compositions for in vivo gene delivery |
DE4238778C2 (de) * | 1992-11-12 | 1995-11-02 | Max Delbrueck Centrum | Vektor zur Expression von therapeutisch relevanten Genen |
US5968735A (en) * | 1992-11-12 | 1999-10-19 | Max Delbruck-Centrum Fur Molekular Medizin Berlin | Vector for the expression of therapy-relevant genes |
US6344445B1 (en) | 1995-10-19 | 2002-02-05 | Cantab Pharmaceutical Research Limited | Herpes virus vectors and their uses |
GB9622500D0 (en) * | 1996-10-29 | 1997-01-08 | Oxford Biomedica Ltd | Therapeutic gene |
GB2333527B (en) * | 1996-10-29 | 2001-05-02 | Oxford Biomedica Ltd | Therapeutic gene |
US6924123B2 (en) | 1996-10-29 | 2005-08-02 | Oxford Biomedica (Uk) Limited | Lentiviral LTR-deleted vector |
EP2895598B1 (fr) | 2012-09-11 | 2019-02-27 | Corning Incorporated | Cellules cryoconservées consommables surexprimant transitoirement un ou des gènes codant pour une ou des protéines transporteurs de médicament et/ou une ou des enzymes de métabolisation d'un médicament |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0095361B1 (fr) * | 1982-05-25 | 1989-07-26 | Eli Lilly And Company | Vecteurs de clonage pour l'expression de protéine exogène |
DE3715033A1 (de) * | 1987-05-06 | 1988-11-17 | Hoechst Ag | Verfahren zur isolierung von fusionsproteinen |
WO1990004632A1 (fr) * | 1988-10-21 | 1990-05-03 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Animaux transgeniques pour tester la resistance a de multiples medicaments |
AU636630B2 (en) * | 1989-06-23 | 1993-05-06 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Efficient method for identifiable expression of non-selectable genes |
-
1989
- 1989-06-02 IL IL9051489A patent/IL90514A/en not_active IP Right Cessation
- 1989-06-02 CA CA000601635A patent/CA1339654C/fr not_active Expired - Fee Related
- 1989-06-05 EP EP89907509A patent/EP0420911B1/fr not_active Expired - Lifetime
- 1989-06-05 DE DE68927104T patent/DE68927104T2/de not_active Expired - Lifetime
- 1989-06-05 WO PCT/US1989/002450 patent/WO1989012109A1/fr active IP Right Grant
- 1989-06-05 AT AT89907509T patent/ATE142269T1/de not_active IP Right Cessation
- 1989-06-05 AU AU37788/89A patent/AU634162B2/en not_active Ceased
- 1989-06-05 JP JP1506880A patent/JP2949440B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH03505818A (ja) | 1991-12-19 |
EP0420911A4 (en) | 1991-11-13 |
DE68927104D1 (de) | 1996-10-10 |
EP0420911B1 (fr) | 1996-09-04 |
WO1989012109A1 (fr) | 1989-12-14 |
AU634162B2 (en) | 1993-02-18 |
DE68927104T2 (de) | 1997-03-06 |
EP0420911A1 (fr) | 1991-04-10 |
JP2949440B2 (ja) | 1999-09-13 |
AU3778889A (en) | 1990-01-05 |
ATE142269T1 (de) | 1996-09-15 |
CA1339654C (fr) | 1998-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |