IL90350A0 - Benzopyran derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents
Benzopyran derivatives,processes for the preparation thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL90350A0 IL90350A0 IL90350A IL9035089A IL90350A0 IL 90350 A0 IL90350 A0 IL 90350A0 IL 90350 A IL90350 A IL 90350A IL 9035089 A IL9035089 A IL 9035089A IL 90350 A0 IL90350 A0 IL 90350A0
- Authority
- IL
- Israel
- Prior art keywords
- processes
- preparation
- same
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888813044A GB8813044D0 (en) | 1988-06-02 | 1988-06-02 | Benzopyran derivatives & processes for preparation thereof |
GB888819449A GB8819449D0 (en) | 1988-08-16 | 1988-08-16 | Benzopyran derivatives & processes for preparation thereof |
GB898900089A GB8900089D0 (en) | 1989-01-04 | 1989-01-04 | Benzopyran derivatives and processes for preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL90350A0 true IL90350A0 (en) | 1989-12-15 |
Family
ID=27263930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL90350A IL90350A0 (en) | 1988-06-02 | 1989-05-19 | Benzopyran derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
Country Status (12)
Country | Link |
---|---|
US (1) | US4988723A (xx) |
EP (1) | EP0344747A1 (xx) |
JP (1) | JPH0242074A (xx) |
KR (1) | KR910000696A (xx) |
CN (1) | CN1038811A (xx) |
AU (1) | AU3523489A (xx) |
DK (1) | DK268189A (xx) |
FI (1) | FI892567A (xx) |
HU (1) | HUT56095A (xx) |
IL (1) | IL90350A0 (xx) |
NO (1) | NO892218L (xx) |
PT (1) | PT90708B (xx) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3823533A1 (de) * | 1988-07-12 | 1990-02-08 | Beiersdorf Ag | Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate |
EP0359537B1 (en) * | 1988-09-16 | 1996-06-26 | Beecham Group Plc | Benzopyran derivatives with antihypertensive activity |
US5104890A (en) * | 1989-03-28 | 1992-04-14 | Fujisawa Pharmaceutical Company, Ltd. | Benzopyran derivatives and processes for preparation thereof |
US5140031A (en) * | 1989-05-31 | 1992-08-18 | E. R. Squibb & Sons, Inc. | Pyranyl cyanoguanidine derivatives |
CA2015296C (en) * | 1989-05-31 | 2001-08-07 | Karnail Atwal | Pyranyl cyanoguanidine derivatives |
US5095016A (en) * | 1989-08-11 | 1992-03-10 | Kaken Pharmaceutical Co., Ltd. | Benzopyran compounds, processes for their production and pharmaceutical compositions |
FR2657872B2 (fr) * | 1989-11-06 | 1992-06-12 | Sanofi Sa | Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant. |
US5061813A (en) * | 1990-04-02 | 1991-10-29 | E. R. Squibb & Sons, Inc. | Substituted cyanoimino benzopyranes |
JP2575226B2 (ja) * | 1990-05-11 | 1997-01-22 | 吉富製薬株式会社 | 光学活性な3,4−ジヒドロ−3,4−エポキシ−2h−1ベンゾピラン化合物の製造法およびその合成中間体 |
US5276168A (en) * | 1990-06-18 | 1994-01-04 | E. R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
US5164509A (en) * | 1990-11-26 | 1992-11-17 | E. R. Squibb & Sons, Inc. | Benzodiazolo analogs |
US5401848A (en) * | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
CA2055376A1 (en) * | 1990-12-05 | 1992-06-06 | Gary J. Grover | Method of treating shock using a potassium channel activator |
US5310932A (en) * | 1991-04-15 | 1994-05-10 | E. R. Squibb & Sons, Inc. | Chromanyl substituted indole potassium channel openers |
WO1993005045A1 (en) * | 1991-08-28 | 1993-03-18 | The Upjohn Company | Spirocyclic benzopyran imidazolines |
US5262419A (en) * | 1992-06-11 | 1993-11-16 | E. R. Squibb & Sons, Inc. | Method for the prophylaxis and/or treatment of ulcerative gastrointestinal conditions using a potassium channel activator |
US5453421A (en) * | 1992-09-11 | 1995-09-26 | E. R. Squibb & Sons, Inc. | Aryl and heterocyclic substituted propenamide derivatives |
US5374643A (en) * | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
US5514690A (en) * | 1992-11-17 | 1996-05-07 | E. R. Squibb & Sons, Inc. | Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline |
US5393771A (en) * | 1993-05-12 | 1995-02-28 | Brisol-Myers Squibb Company | 4-substituted benzopyran and related compounds |
US5837702A (en) * | 1993-10-07 | 1998-11-17 | Bristol-Myers Squibb Co. | 4-arylamino-benzopyran and related compounds |
US5547966A (en) * | 1993-10-07 | 1996-08-20 | Bristol-Myers Squibb Company | Aryl urea and related compounds |
US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
US5612323A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phosphinic ester substituted benzopyran derivatives |
US5612370A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phenylglycine and phenylalaninen amido benzopyran derivatives |
US5629429A (en) * | 1995-06-07 | 1997-05-13 | Bristol-Myers Squibb Company | Process for preparing 4-arylamino-benzopyran and related compounds |
WO2008005368A2 (en) * | 2006-06-30 | 2008-01-10 | Abbott Laboratories | Piperazines as p2x7 antagonists |
WO2010091362A2 (en) * | 2009-02-06 | 2010-08-12 | Mesh Therapeutics, Llc | Topical formulations comprising ion channel modulators |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH427827A (de) * | 1961-11-07 | 1967-01-15 | Bayer Ag | Verfahren zur Herstellung von Imidazolidin-Derivaten |
DE3170604D1 (en) * | 1980-08-21 | 1985-06-27 | Beecham Group Plc | Chromanol derivatives, their production and pharmaceutical compositions containing them |
DE3274350D1 (en) * | 1981-09-25 | 1987-01-08 | Beecham Group Plc | Pharmaceutically active benzopyran compounds |
EP0093534A1 (en) * | 1982-04-28 | 1983-11-09 | Beecham Group Plc | Novel chromanols |
DE3368057D1 (en) * | 1982-05-21 | 1987-01-15 | Beecham Group Plc | Pharmaceutically active aminobenzopyrans |
EP0107423B1 (en) * | 1982-10-19 | 1986-07-23 | Beecham Group Plc | Novel chromans and chromenes |
GB8308062D0 (en) * | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
GB8308064D0 (en) * | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
DE3486354T2 (de) * | 1983-05-18 | 1995-03-30 | Beecham Group Plc | Chroman- und Chromenderivate. |
EP0126311B1 (en) * | 1983-05-18 | 1989-09-13 | Beecham Group Plc | Benzopyran derivatives. |
GB8313679D0 (en) * | 1983-05-18 | 1983-06-22 | Beecham Group Plc | Active compounds |
DE3475786D1 (de) * | 1983-09-01 | 1989-02-02 | Beecham Group Plc | Chromanol derivatives |
DE3477779D1 (en) * | 1983-10-13 | 1989-05-24 | Beecham Group Plc | Chroman derivatives |
ATE56007T1 (de) * | 1984-06-22 | 1990-09-15 | Beecham Group Plc | Wirksame benzopyranverbindungen. |
GB8419516D0 (en) * | 1984-07-31 | 1984-09-05 | Beecham Group Plc | Treatment |
-
1989
- 1989-05-17 US US07/352,990 patent/US4988723A/en not_active Expired - Fee Related
- 1989-05-19 IL IL90350A patent/IL90350A0/xx unknown
- 1989-05-26 FI FI892567A patent/FI892567A/fi not_active Application Discontinuation
- 1989-05-26 AU AU35234/89A patent/AU3523489A/en not_active Abandoned
- 1989-05-31 CN CN89103832A patent/CN1038811A/zh active Pending
- 1989-05-31 EP EP89109845A patent/EP0344747A1/en not_active Ceased
- 1989-06-01 DK DK268189A patent/DK268189A/da not_active Application Discontinuation
- 1989-06-01 KR KR1019890007505A patent/KR910000696A/ko not_active Application Discontinuation
- 1989-06-01 PT PT90708A patent/PT90708B/pt not_active IP Right Cessation
- 1989-06-01 HU HU892811A patent/HUT56095A/hu unknown
- 1989-06-01 NO NO89892218A patent/NO892218L/no unknown
- 1989-06-02 JP JP1141971A patent/JPH0242074A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NO892218L (no) | 1989-12-04 |
AU3523489A (en) | 1989-12-07 |
DK268189D0 (da) | 1989-06-01 |
PT90708B (pt) | 1993-12-31 |
PT90708A (pt) | 1989-12-29 |
HUT56095A (en) | 1991-07-29 |
US4988723A (en) | 1991-01-29 |
KR910000696A (ko) | 1991-01-30 |
EP0344747A1 (en) | 1989-12-06 |
CN1038811A (zh) | 1990-01-17 |
FI892567A (fi) | 1989-12-03 |
JPH0242074A (ja) | 1990-02-13 |
FI892567A0 (fi) | 1989-05-26 |
DK268189A (da) | 1989-12-03 |
NO892218D0 (no) | 1989-06-01 |
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