IL89719A0 - Electrical detection of the immune reaction - Google Patents

Electrical detection of the immune reaction

Info

Publication number
IL89719A0
IL89719A0 IL89719A IL8971989A IL89719A0 IL 89719 A0 IL89719 A0 IL 89719A0 IL 89719 A IL89719 A IL 89719A IL 8971989 A IL8971989 A IL 8971989A IL 89719 A0 IL89719 A0 IL 89719A0
Authority
IL
Israel
Prior art keywords
immune reaction
electrical detection
electrical
detection
immune
Prior art date
Application number
IL89719A
Other languages
English (en)
Original Assignee
Gen Electric
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Electric filed Critical Gen Electric
Publication of IL89719A0 publication Critical patent/IL89719A0/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/817Enzyme or microbe electrode
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/806Electrical property or magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL89719A 1988-05-20 1989-03-23 Electrical detection of the immune reaction IL89719A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/196,718 US4920047A (en) 1988-05-20 1988-05-20 Electrical detection of the immune reaction

Publications (1)

Publication Number Publication Date
IL89719A0 true IL89719A0 (en) 1989-09-28

Family

ID=22726568

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89719A IL89719A0 (en) 1988-05-20 1989-03-23 Electrical detection of the immune reaction

Country Status (5)

Country Link
US (1) US4920047A (ja)
EP (1) EP0342382A3 (ja)
JP (1) JPH0224548A (ja)
IL (1) IL89719A0 (ja)
NO (1) NO892020L (ja)

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CA2027694C (en) * 1989-10-20 2002-03-05 Tadashi Matsunaga Process and apparatus for detecting sensitized leukocyte or antigen
US5187096A (en) * 1991-08-08 1993-02-16 Rensselaer Polytechnic Institute Cell substrate electrical impedance sensor with multiple electrode array
AU6292494A (en) * 1993-03-31 1994-10-24 Dkk Corporation Immunoassay and immunoassay cell used therefor
GB2276724A (en) * 1993-03-31 1994-10-05 Cambridge Life Sciences Electrochemical detection of specific binding species
WO1994028414A1 (en) * 1993-05-29 1994-12-08 Cambridge Life Sciences Plc Sensors based on polymer transformation
US5981203A (en) * 1994-04-26 1999-11-09 The Regents Of The University Of Michigan Unitary sandwich enzyme immunoassay cassette, device and method of use
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
AUPM950094A0 (en) 1994-11-16 1994-12-08 Australian Membrane And Biotechnology Research Institute Detection device and method
AU1360297A (en) * 1996-01-11 1997-08-01 Australian Membrane And Biotechnology Research Institute Ion channel sensor typing
US6348319B1 (en) * 1996-02-08 2002-02-19 Australian Membrane And Biotechnology Research Institute Enzyme detection biosensors
AUPN980796A0 (en) * 1996-05-13 1996-06-06 Australian Membrane And Biotechnology Research Institute Improved reservoir components
US7393645B2 (en) * 1996-11-05 2008-07-01 Clinical Micro Sensors, Inc. Compositions for the electronic detection of analytes utilizing monolayers
US7014992B1 (en) * 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
US5981268A (en) * 1997-05-30 1999-11-09 Board Of Trustees, Leland Stanford, Jr. University Hybrid biosensors
US6013459A (en) * 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
AU744503B2 (en) * 1997-06-12 2002-02-28 Clinical Micro Sensors, Inc. Electronic methods for the detection of analytes
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US6508803B1 (en) 1998-11-06 2003-01-21 Furukawa Techno Material Co., Ltd. Niti-type medical guide wire and method of producing the same
US6432723B1 (en) 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes
US7312087B2 (en) * 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US20020177135A1 (en) * 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
US6852525B1 (en) 1999-11-02 2005-02-08 Advanced Sensor Technologies Mammalian cell culture chamber
US6361958B1 (en) * 1999-11-12 2002-03-26 Motorola, Inc. Biochannel assay for hybridization with biomaterial
US6875619B2 (en) 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
US6824669B1 (en) * 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
US6602400B1 (en) 2000-06-15 2003-08-05 Motorola, Inc. Method for enhanced bio-conjugation events
WO2002012558A1 (en) * 2000-08-07 2002-02-14 Azur Environmental Ltd. Method of an apparatus for the detection of analytes
US6835552B2 (en) * 2000-12-14 2004-12-28 The Regents Of The University Of California Impedance measurements for detecting pathogens attached to antibodies
WO2002054052A1 (en) * 2001-01-08 2002-07-11 Leonard Fish Diagnostic instruments and methods for detecting analytes
US20050009101A1 (en) * 2001-05-17 2005-01-13 Motorola, Inc. Microfluidic devices comprising biochannels
US20030175947A1 (en) * 2001-11-05 2003-09-18 Liu Robin Hui Enhanced mixing in microfluidic devices
US7468255B2 (en) * 2002-12-20 2008-12-23 Acea Biosciences Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology
US7192752B2 (en) 2002-12-20 2007-03-20 Acea Biosciences Real time electronic cell sensing systems and applications for cell-based assays
US7470533B2 (en) 2002-12-20 2008-12-30 Acea Biosciences Impedance based devices and methods for use in assays
US7732127B2 (en) * 2002-12-20 2010-06-08 Acea Biosciences, Inc. Dynamic monitoring of cell adhesion and spreading using the RT-CES system
JP4745056B2 (ja) * 2002-07-20 2011-08-10 アセア バイオサイエンシーズ,インク. インピーダンスによる細胞と微粒子の測定装置及び方法
US8263375B2 (en) 2002-12-20 2012-09-11 Acea Biosciences Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
US8206903B2 (en) 2002-12-20 2012-06-26 Acea Biosciences Device and method for electroporation-based delivery of molecules into cells and dynamic monitoring of cell responses
US7560269B2 (en) * 2002-12-20 2009-07-14 Acea Biosciences, Inc. Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
US20040011650A1 (en) * 2002-07-22 2004-01-22 Frederic Zenhausern Method and apparatus for manipulating polarizable analytes via dielectrophoresis
US20040018611A1 (en) * 2002-07-23 2004-01-29 Ward Michael Dennis Microfluidic devices for high gradient magnetic separation
US11346797B2 (en) 2002-12-20 2022-05-31 Agilent Technologies, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
US10215748B2 (en) 2002-12-20 2019-02-26 Acea Biosciences, Inc. Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways
US10551371B2 (en) 2003-11-10 2020-02-04 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
US10539523B2 (en) 2002-12-20 2020-01-21 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties
DE102005019191A1 (de) * 2005-04-26 2006-11-09 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Detektion der Abdichtung mittels Rauschanalyse
US8041515B2 (en) * 2006-09-20 2011-10-18 Acea Biosciences, Inc. Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
CN101038284B (zh) 2007-04-25 2011-04-27 博奥生物有限公司 一种提高电阻抗检测装置的电阻抗检测灵敏度的方法
CN101556273B (zh) * 2008-04-08 2013-03-20 博奥生物有限公司 利用电阻抗传感技术分析细胞迁移的方法及其专用装置
CA2723223C (en) 2008-05-05 2017-06-06 Acea Biosciences, Inc. Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
CN101614729B (zh) * 2008-06-27 2013-04-24 博奥生物有限公司 用于细胞操作及电生理信号检测的微电极阵列器件及专用装置
WO2011146531A1 (en) 2010-05-18 2011-11-24 Acea Biosciences, Inc Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (rtca) cardio instruments
US12066428B2 (en) 2015-11-20 2024-08-20 Agilent Technologies, Inc. Cell-substrate impedance monitoring of cancer cells
CN110582569B (zh) 2017-03-03 2024-04-02 安捷伦科技有限公司 用于iPSC和ESC衍生的心肌细胞的功能成熟的方法和系统
US10830724B2 (en) 2017-12-22 2020-11-10 International Business Machines Corporation Micro-capacitance sensor array containing spaced apart first and second overlapping and parallel electrode plates for sensing analytes
USD941488S1 (en) 2020-02-07 2022-01-18 Agilent Technologies, Inc. Instrument for analyzing biological cells
US20210301245A1 (en) 2020-03-29 2021-09-30 Agilent Technologies, Inc. Systems and methods for electronically and optically monitoring biological samples

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US4054646A (en) * 1973-07-30 1977-10-18 General Electric Method and apparatus for detection of antibodies and antigens
SE407115B (sv) * 1975-10-06 1979-03-12 Kabi Ab Forfarande och metelektroder for studium av enzymatiska och andra biokemiska reaktioner
DE2711270A1 (de) * 1976-03-16 1977-09-22 Ici Ltd Organische materialien mit spezifisch reaktiven gruppen
EP0085276A1 (de) * 1981-12-10 1983-08-10 Greiner Electronics Ag Verfahren zur immunchemischen Bestimmung einer Substanz
US4490216A (en) * 1983-02-03 1984-12-25 Molecular Devices Corporation Lipid membrane electroanalytical elements and method of analysis therewith
GB2136130B (en) * 1983-02-28 1987-02-11 Theodore Henry Krueger Chemical assay systems and methods
FR2598227B1 (fr) * 1986-04-30 1989-07-28 Bio Merieux Procede de detection et/ou d'identification d'une substance biologique dans un milieu liquide a l'aide de mesures electriques, et dispositif destine a la mise en oeuvre de ce procede

Also Published As

Publication number Publication date
JPH0224548A (ja) 1990-01-26
EP0342382A3 (en) 1990-10-31
NO892020L (no) 1989-11-21
US4920047A (en) 1990-04-24
EP0342382A2 (en) 1989-11-23
NO892020D0 (no) 1989-05-19

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