IL89712A0 - Method for producing 2'''-o-demethyltylosin - Google Patents

Method for producing 2'''-o-demethyltylosin

Info

Publication number
IL89712A0
IL89712A0 IL89712A IL8971289A IL89712A0 IL 89712 A0 IL89712 A0 IL 89712A0 IL 89712 A IL89712 A IL 89712A IL 8971289 A IL8971289 A IL 8971289A IL 89712 A0 IL89712 A0 IL 89712A0
Authority
IL
Israel
Prior art keywords
demethyltylosin
producing
Prior art date
Application number
IL89712A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL89712A0 publication Critical patent/IL89712A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
IL89712A 1988-03-28 1989-03-22 Method for producing 2'''-o-demethyltylosin IL89712A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/173,860 US5063155A (en) 1988-03-28 1988-03-28 Method for producing 2"'-o-demethyltylosin

Publications (1)

Publication Number Publication Date
IL89712A0 true IL89712A0 (en) 1989-09-28

Family

ID=22633827

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89712A IL89712A0 (en) 1988-03-28 1989-03-22 Method for producing 2'''-o-demethyltylosin

Country Status (5)

Country Link
US (1) US5063155A (de)
EP (1) EP0335573A3 (de)
JP (1) JPH0216993A (de)
DK (1) DK142989A (de)
IL (1) IL89712A0 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558942B1 (en) 1994-05-06 2003-05-06 The Leland Stanford Junior University Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
US6066721A (en) * 1995-07-06 2000-05-23 Stanford University Method to produce novel polyketides
US6500960B1 (en) 1995-07-06 2002-12-31 Stanford University (Board Of Trustees Of The Leland Stanford Junior University) Method to produce novel polyketides
US5622866A (en) * 1994-06-23 1997-04-22 Merck & Co., Inc. Expression cassettes useful in construction of integrative and replicative expression vectors for Streptomyces
IL122859A0 (en) * 1995-07-06 1998-08-16 Univ Leland Stanford Junior Cell-free synthesis of polyketides
WO1997022711A1 (en) 1995-12-19 1997-06-26 Regents Of The University Of Minnesota Metabolic engineering of polyhydroxyalkanoate monomer synthases
CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
US6902913B2 (en) 1997-04-30 2005-06-07 Kosan Biosciences, Inc. Recombinant narbonolide polyketide synthase
US6503741B1 (en) 1998-05-28 2003-01-07 Kosan Biosciences, Inc. Polyketide synthase genes from Streptomyces venezuelae
US6117659A (en) * 1997-04-30 2000-09-12 Kosan Biosciences, Inc. Recombinant narbonolide polyketide synthase
US6280999B1 (en) 1998-01-23 2001-08-28 Kosan Bioscience Sorangium polyketide synthases and encoding DNA therefor
US6090601A (en) * 1998-01-23 2000-07-18 Kosan Bioscience Sorangium polyketide synthase
US6265202B1 (en) 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin
US6150513A (en) * 1998-09-16 2000-11-21 Kosan Biosciences, Inc. Polyketide synthase enzymes and recombinant DNA constructs therefor
IL142165A0 (en) * 1998-10-02 2002-03-10 Kosan Biosciences Inc Polyketide synthase enzymes and recombinant dna constructs therefor
JP2002528467A (ja) * 1998-10-28 2002-09-03 コーサン バイオサイエンシーズ, インコーポレイテッド 新規な「不自然な(unnatural)」天然生成物のライブラリ
US6596875B2 (en) 2000-02-07 2003-07-22 James David White Method for synthesizing epothilones and epothilone analogs
US7001748B2 (en) * 1999-02-09 2006-02-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of making polyketides using hybrid polyketide synthases
JP2002536014A (ja) 1999-02-09 2002-10-29 ザ、ボード、オブ、トラスティーズ、オブ、ザ、リーランド、スタンフォード、ジュニア、ユニバーシティ ポリケチドシンターゼモジュールの有効性を媒介する方法
US6569867B2 (en) 1999-10-01 2003-05-27 Kosan Biosciences, Inc. Polyketide derivatives
EP2210948A3 (de) 1999-12-10 2010-10-06 Life Technologies Corporation Verwendung von mehrfachen Rekombinationsstellen mit einzigartiger Spezifizität beim Rekombinationsklonen
US20030194784A1 (en) * 2001-04-17 2003-10-16 Sherman David H. DNA encoding methymycin and pikromycin
EP1381685B1 (de) * 2001-04-26 2005-09-14 Ecopia Biosciences Inc. Gene und proteine für polyketide biosynthese
US20070203346A1 (en) * 2001-04-30 2007-08-30 Oregon State University Method for synthesizing epothilones and epothilone analogs
WO2003010193A2 (en) * 2001-07-26 2003-02-06 Ecopia Biosciences Inc. Genes and proteins for the biosynthesis of rosaramicin
US20060110789A1 (en) * 2002-03-04 2006-05-25 Gokhale Rajesh S Methods to mediate polyketide synthase module effectiveness
US7364877B2 (en) * 2002-12-06 2008-04-29 Kosan Biosciences, Inc. Polynucleotides encoding disorazole polyketide synthase polypeptides
KR100549690B1 (ko) 2003-10-23 2006-02-07 상하이 지아오통 대학 에프알-008 폴리케타이드 합성에 관여하는 유전자
US7229814B2 (en) * 2004-05-05 2007-06-12 Regents Of The University Of Minnesota Nucleic acids and polypeptides involved in the production of cryptophycin
US7566558B2 (en) * 2006-07-28 2009-07-28 Regents Of The University Of Michigan Nucleic acids and polypeptides involved in the production of cryptophycin
US8759031B2 (en) * 2007-04-12 2014-06-24 Wisconsin Alumni Research Foundation Type I polyketide synthase extender units

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340599C (en) * 1986-03-21 1999-06-22 Karen Leigh Cox Antibiotic-producing microorganisms

Also Published As

Publication number Publication date
DK142989D0 (da) 1989-03-22
DK142989A (da) 1989-10-12
EP0335573A3 (de) 1991-04-10
EP0335573A2 (de) 1989-10-04
JPH0216993A (ja) 1990-01-19
US5063155A (en) 1991-11-05

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