IL89278A - Tetrazolyl alkyl (or alkenyl) piperidine carboxylic acid derivatives, process for their preparation and excitatory amino acid receptor antagonist compositions containing them - Google Patents
Tetrazolyl alkyl (or alkenyl) piperidine carboxylic acid derivatives, process for their preparation and excitatory amino acid receptor antagonist compositions containing themInfo
- Publication number
- IL89278A IL89278A IL89278A IL8927889A IL89278A IL 89278 A IL89278 A IL 89278A IL 89278 A IL89278 A IL 89278A IL 8927889 A IL8927889 A IL 8927889A IL 89278 A IL89278 A IL 89278A
- Authority
- IL
- Israel
- Prior art keywords
- amino acid
- alkenyl
- preparation
- excitatory amino
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15776088A | 1988-02-19 | 1988-02-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL89278A0 IL89278A0 (en) | 1989-09-10 |
| IL89278A true IL89278A (en) | 1993-03-15 |
Family
ID=22565157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL89278A IL89278A (en) | 1988-02-19 | 1989-02-14 | Tetrazolyl alkyl (or alkenyl) piperidine carboxylic acid derivatives, process for their preparation and excitatory amino acid receptor antagonist compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0330353B1 (da) |
| JP (1) | JPH01249767A (da) |
| CN (1) | CN1022244C (da) |
| AT (1) | ATE87918T1 (da) |
| AU (1) | AU608692B2 (da) |
| CA (1) | CA1332239C (da) |
| DE (1) | DE68905845T2 (da) |
| DK (1) | DK70289A (da) |
| ES (1) | ES2055036T3 (da) |
| HU (1) | HU202226B (da) |
| IE (1) | IE62645B1 (da) |
| IL (1) | IL89278A (da) |
| MX (1) | MX14957A (da) |
| NZ (1) | NZ227979A (da) |
| PH (1) | PH27562A (da) |
| PT (1) | PT89713B (da) |
| RU (1) | RU2015976C1 (da) |
| ZA (1) | ZA891113B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4968678A (en) * | 1988-02-19 | 1990-11-06 | Eli Lilly And Company | Tetrazole excitatory amino acid receptor antagonists |
| US4902695A (en) * | 1989-02-13 | 1990-02-20 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| US5238958A (en) * | 1990-02-26 | 1993-08-24 | Warner-Lambert Company | Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals |
| ATE231505T1 (de) * | 1991-03-28 | 2003-02-15 | Eisai Co Ltd | Neue heterocyclische/cyclische amine |
| CA2159326C (en) * | 1993-03-29 | 2000-05-30 | Robert Kisilevsky | Method for treating amyloidosis |
| US20040208875A1 (en) | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
| US6022868A (en) * | 1995-06-29 | 2000-02-08 | Novo Nordisk Als | Substituted azacyclic or azabicyclic compounds |
| US5880138A (en) * | 1996-10-01 | 1999-03-09 | Eli Lilly And Company | NMDA receptor selective antagonists |
| US7056917B2 (en) | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
| US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US8044100B2 (en) | 2004-12-22 | 2011-10-25 | Bellus Health Inc. | Methods and compositions for treating amyloid-related diseases |
| TW200716088A (en) | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| MX2008008213A (es) | 2005-12-22 | 2008-09-03 | Neurochem Int Ltd | Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias. |
| DK2089417T3 (da) | 2006-10-12 | 2015-03-23 | Bhi Ltd Partnership | Fremgangsmåder, forbindelser, sammensætninger og vehikler til afgivelse af 3-amion-1-propansulfonsyre |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1248531A (en) * | 1984-04-17 | 1989-01-10 | Jeffrey C. Watkins | 4-substituted piperazine-2-carboxylic acids |
| PH23848A (en) * | 1985-05-24 | 1989-11-23 | Ciba Geigy Ag | Certain phosphonic acids and derivatives |
| US4746653A (en) * | 1986-02-28 | 1988-05-24 | Ciba-Geigy Corporation | Certain hetero phosphonic acid derivatives of 2-piperidine or 2-tetrahydropyridinecarboxylates and esters thereof which are useful for the treatment of disorders responsive to blockade of the NMDA receptor in mammals |
| GB8714789D0 (en) * | 1987-06-24 | 1987-07-29 | Lundbeck & Co As H | Heterocyclic compounds |
| US4968678A (en) * | 1988-02-19 | 1990-11-06 | Eli Lilly And Company | Tetrazole excitatory amino acid receptor antagonists |
-
1989
- 1989-02-13 ZA ZA891113A patent/ZA891113B/xx unknown
- 1989-02-13 ES ES89301337T patent/ES2055036T3/es not_active Expired - Lifetime
- 1989-02-13 EP EP89301337A patent/EP0330353B1/en not_active Expired - Lifetime
- 1989-02-13 AT AT89301337T patent/ATE87918T1/de not_active IP Right Cessation
- 1989-02-13 DE DE8989301337T patent/DE68905845T2/de not_active Expired - Fee Related
- 1989-02-14 NZ NZ227979A patent/NZ227979A/xx unknown
- 1989-02-14 PT PT89713A patent/PT89713B/pt active IP Right Grant
- 1989-02-14 IL IL89278A patent/IL89278A/xx not_active IP Right Cessation
- 1989-02-14 CA CA000590966A patent/CA1332239C/en not_active Expired - Fee Related
- 1989-02-15 DK DK070289A patent/DK70289A/da not_active Application Discontinuation
- 1989-02-16 MX MX1495789A patent/MX14957A/es unknown
- 1989-02-16 HU HU89777A patent/HU202226B/hu not_active IP Right Cessation
- 1989-02-17 CN CN89100897A patent/CN1022244C/zh not_active Expired - Fee Related
- 1989-02-17 RU SU894613482A patent/RU2015976C1/ru active
- 1989-02-17 IE IE51889A patent/IE62645B1/en not_active IP Right Cessation
- 1989-02-17 JP JP1039169A patent/JPH01249767A/ja active Pending
- 1989-02-17 AU AU30090/89A patent/AU608692B2/en not_active Ceased
-
1990
- 1990-08-17 PH PH41044A patent/PH27562A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT49603A (en) | 1989-10-30 |
| IE62645B1 (en) | 1995-02-22 |
| JPH01249767A (ja) | 1989-10-05 |
| DE68905845T2 (de) | 1993-08-05 |
| ES2055036T3 (es) | 1994-08-16 |
| EP0330353B1 (en) | 1993-04-07 |
| CA1332239C (en) | 1994-10-04 |
| DE68905845D1 (de) | 1993-05-13 |
| MX14957A (es) | 1993-11-01 |
| AU608692B2 (en) | 1991-04-11 |
| RU2015976C1 (ru) | 1994-07-15 |
| PT89713A (pt) | 1989-10-04 |
| AU3009089A (en) | 1989-08-24 |
| ATE87918T1 (de) | 1993-04-15 |
| PH27562A (en) | 1993-08-18 |
| DK70289A (da) | 1989-08-21 |
| EP0330353A1 (en) | 1989-08-30 |
| DK70289D0 (da) | 1989-02-15 |
| CN1022244C (zh) | 1993-09-29 |
| PT89713B (pt) | 1994-04-29 |
| IE890518L (en) | 1989-08-19 |
| HU202226B (en) | 1991-02-28 |
| IL89278A0 (en) | 1989-09-10 |
| ZA891113B (en) | 1990-10-31 |
| NZ227979A (en) | 1991-02-26 |
| CN1035114A (zh) | 1989-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |