IL88016A0 - Liquid ibuprofen compositions and methods of making them - Google Patents

Liquid ibuprofen compositions and methods of making them

Info

Publication number
IL88016A0
IL88016A0 IL88016A IL8801688A IL88016A0 IL 88016 A0 IL88016 A0 IL 88016A0 IL 88016 A IL88016 A IL 88016A IL 8801688 A IL8801688 A IL 8801688A IL 88016 A0 IL88016 A0 IL 88016A0
Authority
IL
Israel
Prior art keywords
making
methods
ibuprofen compositions
liquid ibuprofen
compositions
Prior art date
Application number
IL88016A
Other languages
English (en)
Original Assignee
Oratech Pharm Dev Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oratech Pharm Dev Corp filed Critical Oratech Pharm Dev Corp
Publication of IL88016A0 publication Critical patent/IL88016A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL88016A 1987-10-15 1988-10-12 Liquid ibuprofen compositions and methods of making them IL88016A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/110,184 US4861797A (en) 1987-10-15 1987-10-15 Liquid ibuprofen compositions and methods of making them

Publications (1)

Publication Number Publication Date
IL88016A0 true IL88016A0 (en) 1989-06-30

Family

ID=22331654

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88016A IL88016A0 (en) 1987-10-15 1988-10-12 Liquid ibuprofen compositions and methods of making them

Country Status (5)

Country Link
US (1) US4861797A (xx)
EP (1) EP0340289A4 (xx)
JP (1) JPH02501657A (xx)
IL (1) IL88016A0 (xx)
WO (1) WO1989003210A1 (xx)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859704A (en) * 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
GB8920693D0 (en) * 1989-09-13 1989-10-25 Nicholas Kiwi Pty Ltd Non-effervescent ibuprofen compositions
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
RO118371B1 (ro) * 1991-05-13 2003-05-30 Boots Co Plc Compozitie farmaceutica continand sare de sodiu a s (-)ibuprofen
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
DE4140172C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Ibuprofen enthaltendes Arzneimittel
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
IT1256616B (it) * 1992-12-02 1995-12-12 Zambon Spa Sciroppo contenente n-acetil-cisteina
US5981591A (en) * 1992-12-04 1999-11-09 Mayor Pharmaceutical Laboratories, Inc. Sprayable analgesic composition and method of use
SK74396A3 (en) * 1995-06-13 1997-04-09 American Home Prod Organoleptically acceptable oral pharmaceutical compositions
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
US6767925B1 (en) 1996-10-31 2004-07-27 Joseph A. Deihl Sprayable analgesic composition and method of use
AU6855198A (en) * 1997-04-21 1998-11-13 Taisho Pharmaceutical Co., Ltd. Ibuprofen suspension preparations
US6060062A (en) * 1997-06-26 2000-05-09 Fowler; Pearline Liquid composition for the topical application to relieve arthritic pain
EP1321140B1 (en) * 2000-08-25 2005-04-06 Kowa Company, Ltd. Ibuprofen solutions for capsule-filling and capsule preparations
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US7090859B2 (en) * 2002-12-13 2006-08-15 Ronald Thomas Haas Ketoprofen compositions and methods of making them
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
WO2007035448A2 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
US7582679B2 (en) * 2006-02-03 2009-09-01 Pharmaceutics International Incorporated Compositions containing solid ibuprofen concentrates and methods of making solid ibuprofen concentrates
BRPI0707698A2 (pt) * 2006-02-06 2011-05-10 Pharmaceutical Solutions Inc preparaÇÕes nço esteroidais antiinflamatàrias orais lÍquidas e em pà para administraÇço a animais
CL2007002425A1 (es) * 2006-08-22 2008-06-27 Albermarle Corp Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
WO2009091622A1 (en) * 2008-01-18 2009-07-23 Dow Global Technologies Inc. Method to enhance aqueous solubility of poorly soluble actives using methoxypolyethylene glycol
MX337488B (es) * 2008-07-21 2016-03-08 Si Group Inc Granulos con alto contenido de ibuprofeno sodico, su preparacion y su uso en preparar formas de dosificacion solidas no efervescentes.
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
ES2694506T3 (es) 2009-03-12 2018-12-21 Cumberland Pharmaceuticals Inc. Administración de ibuprofeno por vía intravenosa
US8735452B2 (en) * 2009-07-15 2014-05-27 Cumberland Pharmaceuticals Inc. Treating patients with intravenous ibuprofen
US8871810B2 (en) 2009-07-15 2014-10-28 Cumberland Pharmaceuticals Inc. Treating critically ill patients with intravenous ibuprofen
MY174442A (en) * 2009-07-31 2020-04-18 Cumberland Pharmaceuticals Inc Treating critically ill patients with intravenous ibuprofen
US9072661B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
KR101777587B1 (ko) 2012-03-16 2017-09-13 큠버랜드 파마슈티컬즈 인코포레이티드 주사가능한 이부프로펜 제제
US9072710B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation

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US3041239A (en) * 1959-05-28 1962-06-26 Johnson & Johnson Stable aqueous salicylamide composition and method of preparing same
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
CH524372A (de) * 1969-01-29 1972-06-30 Ciba Geigy Ag Verfahren zur Herstellung von stabilen Elixieren, welche therapeutisch verwendbare tricyclische basische Wirkstoffe in Form ihrer Mononatriumpamoate enthalten
JPS5537528B2 (xx) * 1972-12-11 1980-09-29
JPS5831210B2 (ja) * 1973-04-09 1983-07-05 武田薬品工業株式会社 アンテイナスイセイケンダクエキノセイゾウホウ
US3903297A (en) * 1973-11-01 1975-09-02 Upjohn Co Method of treatment and prophylaxis of gastric hypersecretion and gastric and duodenal ulcers using prostaglandin analogs
IL44774A (en) * 1974-05-06 1977-07-31 Baron E Pharmaceutical composition containing acetyl salicyclic acid
US4031243A (en) * 1975-07-03 1977-06-21 Juste, S.A. Quimico-Farmaceutica 2-(4-Isobutyl phenyl)butyric acid, salts thereof, and pharmaceutical compositions containing the same
CA1062721A (en) * 1975-12-15 1979-09-18 Anthony A. Sinkula Propionic acid derivatives
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
US4344929A (en) * 1980-04-25 1982-08-17 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4282252A (en) * 1980-05-15 1981-08-04 Thomas Jefferson University Method of increasing coronary blood flow with ibuprofen
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
US4346108A (en) * 1981-06-22 1982-08-24 The Upjohn Manufacturing Company M Method for preventing adhesion formation
JPS584720A (ja) * 1981-06-26 1983-01-11 ザ・アツプジヨン・カンパニ− 鎮痛用医薬組成物
US4447451A (en) * 1981-07-20 1984-05-08 The Upjohn Manufacturing Company M Treatment of adult respiratory distress syndrome
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IT1198351B (it) * 1981-09-21 1988-12-21 Montedison Spa Processo per la carbonilazione di alogenuri benzilici secondari
IT1139455B (it) * 1981-09-21 1986-09-24 Montedison Spa Processo per la preparazione di acidi alfa-arilpropionici e loro sali alcalini
US4713249A (en) * 1981-11-12 1987-12-15 Schroeder Ulf Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
DE3205504C2 (de) * 1982-02-16 1983-12-01 Dolorgiet Gmbh & Co Kg, 5300 Bonn Äußerlich anwendbares, Ibuprofen enthaltendes Arzneimittel
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4404210A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and ibuprofen
US4447443A (en) * 1982-11-15 1984-05-08 Merck & Co., Inc. Anti-inflammatory/analgesic combination of α-fluoromethylhistidine and a selected non-steroidal anti-inflammatory drug (NSAID)
US4599359A (en) * 1982-12-09 1986-07-08 Stephen A. Cooper Hydroxyzine-containing analgesic combinations
US4439450A (en) * 1983-06-30 1984-03-27 The Upjohn Manufacturing Company M Treatment of the blood-brain barrier with ibuprofen
JPH0647532B2 (ja) * 1983-08-31 1994-06-22 ジ アツプジヨン カンパニ− 歯槽骨吸収の治療
US4558051A (en) * 1983-10-11 1985-12-10 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4717713A (en) * 1983-10-31 1988-01-05 Research Corporation Controlled release liquid pharmaceutical
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
DE3437599C2 (de) * 1984-10-13 1987-04-16 Dolorgiet GmbH & Co KG, 5205 St Augustin Ibuprofen enthaltende Weichgelatinekapseln
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Also Published As

Publication number Publication date
EP0340289A4 (en) 1991-03-13
EP0340289A1 (en) 1989-11-08
JPH02501657A (ja) 1990-06-07
WO1989003210A1 (en) 1989-04-20
US4861797A (en) 1989-08-29

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