IL87122A0 - Substituted thienoinidazole derivatives,process for the preparation thereof,pharmaceutical compositions containing them,and the use thereof as inhibitors of gastric acid secretion,as gastroprotectives and as medicaments for intestinal inflammations - Google Patents

Substituted thienoinidazole derivatives,process for the preparation thereof,pharmaceutical compositions containing them,and the use thereof as inhibitors of gastric acid secretion,as gastroprotectives and as medicaments for intestinal inflammations

Info

Publication number
IL87122A0
IL87122A0 IL87122A IL8712288A IL87122A0 IL 87122 A0 IL87122 A0 IL 87122A0 IL 87122 A IL87122 A IL 87122A IL 8712288 A IL8712288 A IL 8712288A IL 87122 A0 IL87122 A0 IL 87122A0
Authority
IL
Israel
Prior art keywords
thienoinidazole
gastroprotectives
medicaments
inhibitors
derivatives
Prior art date
Application number
IL87122A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL87122A0 publication Critical patent/IL87122A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL87122A 1987-07-15 1988-07-15 Substituted thienoinidazole derivatives,process for the preparation thereof,pharmaceutical compositions containing them,and the use thereof as inhibitors of gastric acid secretion,as gastroprotectives and as medicaments for intestinal inflammations IL87122A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873723327 DE3723327A1 (de) 1987-07-15 1987-07-15 Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen

Publications (1)

Publication Number Publication Date
IL87122A0 true IL87122A0 (en) 1988-12-30

Family

ID=6331583

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87122A IL87122A0 (en) 1987-07-15 1988-07-15 Substituted thienoinidazole derivatives,process for the preparation thereof,pharmaceutical compositions containing them,and the use thereof as inhibitors of gastric acid secretion,as gastroprotectives and as medicaments for intestinal inflammations

Country Status (15)

Country Link
US (1) US4956366A (fr)
EP (1) EP0299389A3 (fr)
JP (1) JPS6431785A (fr)
KR (1) KR890002107A (fr)
AU (1) AU618540B2 (fr)
DE (1) DE3723327A1 (fr)
DK (1) DK393788A (fr)
FI (1) FI883342A (fr)
HU (1) HU201078B (fr)
IL (1) IL87122A0 (fr)
NO (1) NO167980C (fr)
NZ (1) NZ225387A (fr)
PH (1) PH26118A (fr)
PT (1) PT87986A (fr)
ZA (1) ZA885093B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
US5271944A (en) * 1991-04-05 1993-12-21 Biofor, Ltd. Pharmacologically enhanced formulations
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
KR100441901B1 (ko) * 2001-07-02 2004-07-27 일동제약주식회사 세팔로스포린 유도체의 개선된 제조방법
WO2004012659A2 (fr) * 2002-08-01 2004-02-12 Nitromed, Inc. Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation
CN102675217A (zh) * 2012-05-24 2012-09-19 盛世泰科生物医药技术(苏州)有限公司 一种5-溴-2-甲基-4(1h)-嘧啶酮的制备方法
US9068530B2 (en) 2013-03-15 2015-06-30 Mahle International Gmbh Connecting rod with lubrication passage
MX2017002610A (es) 2014-08-29 2017-10-11 Tes Pharma S R L INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA.
WO2024075017A1 (fr) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition de calcification de valve aortique

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4055647A (en) * 1973-06-14 1977-10-25 Ciba-Geigy Corporation Condensed pyrrole mercapto compounds having hypotensive and decongestant properties
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
EP0178438A1 (fr) * 1984-09-19 1986-04-23 Beecham Group Plc Composés
DK8600939A (fr) * 1985-03-05 1986-09-06
FI861772A (fi) * 1985-05-07 1986-11-08 Chemie Linz Ag Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning.
ES2032394T3 (es) * 1986-02-20 1993-02-16 Hoechst Aktiengesellschaft Procedimiento para preparar derivados de tienoimidazol sustituidos.
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer

Also Published As

Publication number Publication date
NO883145L (no) 1989-01-16
NO167980C (no) 1992-01-02
DE3723327A1 (de) 1989-02-02
HU201078B (en) 1990-09-28
FI883342A (fi) 1989-01-16
FI883342A0 (fi) 1988-07-13
US4956366A (en) 1990-09-11
KR890002107A (ko) 1989-04-08
NO167980B (no) 1991-09-23
DK393788D0 (da) 1988-07-14
JPS6431785A (en) 1989-02-02
EP0299389A2 (fr) 1989-01-18
AU618540B2 (en) 1992-01-02
NO883145D0 (no) 1988-07-14
NZ225387A (en) 1990-07-26
AU1903288A (en) 1989-01-19
PT87986A (pt) 1989-06-30
DK393788A (da) 1989-01-16
EP0299389A3 (fr) 1990-05-30
ZA885093B (en) 1989-03-29
PH26118A (en) 1992-02-24

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