IL86856A0 - Bovine xa factor and pharmaceutical compositions containing the same - Google Patents

Bovine xa factor and pharmaceutical compositions containing the same

Info

Publication number
IL86856A0
IL86856A0 IL86856A IL8685688A IL86856A0 IL 86856 A0 IL86856 A0 IL 86856A0 IL 86856 A IL86856 A IL 86856A IL 8685688 A IL8685688 A IL 8685688A IL 86856 A0 IL86856 A0 IL 86856A0
Authority
IL
Israel
Prior art keywords
factor
bovine
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL86856A
Other languages
English (en)
Original Assignee
Yissum Res Dev Co
Univ Jerusalem Hebrew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co, Univ Jerusalem Hebrew filed Critical Yissum Res Dev Co
Priority to IL86856A priority Critical patent/IL86856A0/xx
Publication of IL86856A0 publication Critical patent/IL86856A0/xx
Priority to AT89306345T priority patent/ATE102039T1/de
Priority to US07/370,601 priority patent/US5182113A/en
Priority to ES89306345T priority patent/ES2052916T3/es
Priority to EP89306345A priority patent/EP0352903B1/en
Priority to DE68913383T priority patent/DE68913383T2/de
Priority to JP16362189A priority patent/JP3176604B2/ja
Priority to US08/002,218 priority patent/US5403596A/en
Priority to IL106448A priority patent/IL106448A0/xx
Priority to HK182296A priority patent/HK182296A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855Proteins from animals other than mammals or birds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL86856A 1988-06-24 1988-06-24 Bovine xa factor and pharmaceutical compositions containing the same IL86856A0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IL86856A IL86856A0 (en) 1988-06-24 1988-06-24 Bovine xa factor and pharmaceutical compositions containing the same
AT89306345T ATE102039T1 (de) 1988-06-24 1989-06-23 Rinderfaktor-xa-hemmender faktor und diesen enthaltende pharmazeutische zusammensetzungen.
US07/370,601 US5182113A (en) 1988-06-24 1989-06-23 Factor xa inibitor from leech and pharmaceutical compositions containing same
ES89306345T ES2052916T3 (es) 1988-06-24 1989-06-23 Factor inhibidor del factor xa bovino y composiciones farmaceuticas que lo contienen.
EP89306345A EP0352903B1 (en) 1988-06-24 1989-06-23 Bovine factor Xa inhibiting factor and pharmaceutical compositions containing the same
DE68913383T DE68913383T2 (de) 1988-06-24 1989-06-23 Rinderfaktor-Xa-hemmender Faktor und diesen enthaltende pharmazeutische Zusammensetzungen.
JP16362189A JP3176604B2 (ja) 1988-06-24 1989-06-26 Xa因子インヒビターおよびそれを含有する医薬組成物
US08/002,218 US5403596A (en) 1988-06-24 1993-01-08 Factor Xa inhibitor and pharmaceutical compositions containing same
IL106448A IL106448A0 (en) 1988-06-24 1993-07-22 Factor xa inhibitor and pharmaceutical compositions containing the same
HK182296A HK182296A (en) 1988-06-24 1996-10-03 Bovine factor xa inhibiting factor and pharmaceutical compositions containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL86856A IL86856A0 (en) 1988-06-24 1988-06-24 Bovine xa factor and pharmaceutical compositions containing the same

Publications (1)

Publication Number Publication Date
IL86856A0 true IL86856A0 (en) 1988-11-30

Family

ID=11058977

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86856A IL86856A0 (en) 1988-06-24 1988-06-24 Bovine xa factor and pharmaceutical compositions containing the same

Country Status (8)

Country Link
US (2) US5182113A (ja)
EP (1) EP0352903B1 (ja)
JP (1) JP3176604B2 (ja)
AT (1) ATE102039T1 (ja)
DE (1) DE68913383T2 (ja)
ES (1) ES2052916T3 (ja)
HK (1) HK182296A (ja)
IL (1) IL86856A0 (ja)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4001238A1 (de) * 1990-01-18 1991-07-25 Basf Ag Verfahren zur anreicherung bzw. reinigung von biomolekuelen
CA2047527A1 (en) * 1990-07-24 1992-01-25 Christopher Dunwiddie Method for administering a therapeutic anticoagulant
GB9022040D0 (en) * 1990-10-10 1990-11-21 Biopharm Ltd Platelet adhesion inhibitor
DE4234921A1 (de) * 1992-10-16 1994-04-21 Basf Ag Neues, die Gerinnungszeit des Blutes verlängerndes Protein aus dem Landblutegel Haemadipsa sylestris
US5801017A (en) * 1993-04-09 1998-09-01 Bio-Technology General Corp. Production of recombinant factor Xa inhibitor of leech Hirudo medicinalis
IL109259A0 (en) * 1993-04-09 1994-07-31 Bio Technology General Corp Novel polypeptide having factor Xa inhibitory activity
US5783421A (en) * 1993-04-09 1998-07-21 Bio-Technology General Corp. DNA encoding novel polypeptide having Factor Xa inhibitory activity
CZ287472B6 (en) * 1993-07-01 2000-12-13 Merck Patent Gmbh Purified protein, process of its preparation and use as well as pharmaceutical preparation based thereon
DE4440892A1 (de) * 1994-11-17 1996-05-23 Gruenenthal Gmbh Proteine mit fibrinolytischen und gerinnungshemmenden Eigenschaften
US5919765A (en) * 1995-06-07 1999-07-06 Cor Therapeutics, Inc. Inhibitors of factor XA
US6069130A (en) 1995-06-07 2000-05-30 Cor Therapeutics, Inc. Ketoheterocyclic inhibitors of factor Xa
US6046169A (en) * 1995-06-07 2000-04-04 Cor Therapeutics, Inc. Inhibitors of factor XA
US6022861A (en) * 1995-06-07 2000-02-08 Cor Therapeutics, Inc. Ketoheterocyclic inhibitors of factor Xa
US5721214A (en) * 1995-06-07 1998-02-24 Cor Therapeutics, Inc. Inhibitors of factor Xa
US6245743B1 (en) 1996-06-05 2001-06-12 Cor Therapeutics, Inc. Inhibitors of factor Xa
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
AU6896398A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
AU6896298A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
US6133256A (en) * 1997-04-14 2000-10-17 Cor Therapeutics Inc Selective factor Xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588587A (en) * 1983-03-01 1986-05-13 Pennsylvania Hospital Method of treatment to inhibit metastasis
DE3689525D1 (de) * 1985-07-17 1994-02-24 Hoechst Ag Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel.
JPS63146900A (ja) * 1986-09-18 1988-06-18 ザ コントリビューターズ トゥー ザ ペンシルバニア 抗凝血性及び抗転移性特性を有するタンパク質
US4832849A (en) * 1988-06-16 1989-05-23 Merrell Dow Pharmaceuticals Inc. Extraction and purification of an anticoagulant principle from the south american leech, haementeria ghilianii

Also Published As

Publication number Publication date
EP0352903A3 (en) 1990-06-13
HK182296A (en) 1996-10-11
JPH02111800A (ja) 1990-04-24
ATE102039T1 (de) 1994-03-15
EP0352903B1 (en) 1994-03-02
US5182113A (en) 1993-01-26
DE68913383D1 (de) 1994-04-07
US5403596A (en) 1995-04-04
DE68913383T2 (de) 1994-07-14
ES2052916T3 (es) 1994-07-16
JP3176604B2 (ja) 2001-06-18
EP0352903A2 (en) 1990-01-31

Similar Documents

Publication Publication Date Title
EP0352903A3 (en) Bovine factor xa inhibiting factor and pharmaceutical compositions containing the same
IL89835A0 (en) Substituted azetidinones,their preparation and pharmaceutical compositions containing them
IL89167A0 (en) Substituted pyrroles,their manufacture and pharmaceutical compositions containing them
WO1987003480A3 (fr) Medicament a effet anti-tumoral contenant de l'hexadecylphosphocholine
JPS6413076A (en) Novel compound, manufacture and medicinal composition
EG18379A (en) Novel pharmacological compounds
JPS6413088A (en) Novel compound, manufacture and medicinal composition
UA41332C2 (uk) Білок, здатний інгібувати стимульовану колагеном агрегацію тромбоцитів, спосіб його одержання, фармацевтичний препарат, спосіб обробки імплантованого або екстракорпорального медичного пристрою та спосіб одержання лікарського засобу
IL92672A0 (en) Retroviral protease inhibitors,their preparation and pharmaceutical compositions containing them
AU1866888A (en) Pharmaceutical dosage unit containing 17beta-oestradiol and desogestrel
IL85189A (en) Beta-alkyl substituted melatonins,their preparation and pharmaceutical compositions containing them
IL106289A0 (en) Phospholipid derivatives, their preparation and pharmaceutical compositions containing them
WO1990003394A3 (fr) Nouvelles lymphokines, sequences d'adn codant pour ces lymphokines et compositions pharmaceutiques contenant ces lymphokines
GR862285B (en) Pharmaceutical compositions for treating the high blood pressure
IL70990A0 (en) Pharmaceutical compositions containing glyceryl mononitrates
IL88673A0 (en) N-hydroxy-5-phenyl-2-furancarboxi-midamides,and pharmaceutical compositions containing them
IL89015A (en) Pharmaceutical compositions containing tetrahydropyridine derivatives, certain such novel compounds and their preparation
JPS6483083A (en) Novel compound, manufacture and medicinal composition
IL82780A0 (en) Peptides,their manufacture and pharmaceutical compositions containing them
IL88050A0 (en) Bicyclic peroxides,their manufacture and pharmaceutical compositions containing them
EP0252305A3 (en) Use of avarone and avarol and derivatives thereof for the preparation of a pharmaceutical composition for the control of adult t-cell leukemia/lymphoma
JO1493B1 (en) Pharmaceutical combination for treating high blood pressure
AU6046190A (en) A purified, human autoregulatory cytokine, compositions containing same and uses thereof
NO910071L (no) Polymersammensetning for fjerning av oksygen.
AU5713586A (en) Pharmaceutical composition containing pure san-mai-sen

Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees