IL85587A - Magainin polypeptides active against gram-positive and gram-negative bacteria,fungi,viruses and protozoa and a pharmaceutical composition containing the same - Google Patents

Magainin polypeptides active against gram-positive and gram-negative bacteria,fungi,viruses and protozoa and a pharmaceutical composition containing the same

Info

Publication number
IL85587A
IL85587A IL85587A IL8558788A IL85587A IL 85587 A IL85587 A IL 85587A IL 85587 A IL85587 A IL 85587A IL 8558788 A IL8558788 A IL 8558788A IL 85587 A IL85587 A IL 85587A
Authority
IL
Israel
Prior art keywords
gram
magainin
protozoa
fungi
viruses
Prior art date
Application number
IL85587A
Other languages
English (en)
Other versions
IL85587A0 (en
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/021,493 external-priority patent/US4810777A/en
Application filed by Us Health filed Critical Us Health
Publication of IL85587A0 publication Critical patent/IL85587A0/xx
Publication of IL85587A publication Critical patent/IL85587A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL85587A 1987-03-04 1988-02-29 Magainin polypeptides active against gram-positive and gram-negative bacteria,fungi,viruses and protozoa and a pharmaceutical composition containing the same IL85587A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/021,493 US4810777A (en) 1987-03-04 1987-03-04 Antimicrobial compounds
US7673487A 1987-07-23 1987-07-23
US8179387A 1987-08-05 1987-08-05

Publications (2)

Publication Number Publication Date
IL85587A0 IL85587A0 (en) 1988-08-31
IL85587A true IL85587A (en) 1992-09-06

Family

ID=27361650

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85587A IL85587A (en) 1987-03-04 1988-02-29 Magainin polypeptides active against gram-positive and gram-negative bacteria,fungi,viruses and protozoa and a pharmaceutical composition containing the same

Country Status (9)

Country Link
US (1) US5567681A (fr)
EP (1) EP0362209B1 (fr)
JP (1) JP2555174B2 (fr)
AT (1) ATE106896T1 (fr)
AU (1) AU609118B2 (fr)
CA (1) CA1339387C (fr)
DE (1) DE3850107T2 (fr)
IL (1) IL85587A (fr)
WO (1) WO1988006597A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266562A (en) * 1987-11-19 1993-11-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Anti-inflammatory agents
IL90356A0 (en) * 1988-05-27 1989-12-15 Magainin Sciences Inc Amphiphilic peptides and pharmaceutical compositions containing them
AU641129B2 (en) * 1988-10-21 1993-09-16 Magainin Sciences, Inc. Composition and treatment with biologically active peptides and certain anions
CA2007913A1 (fr) * 1989-01-30 1990-07-30 Michael Zasloff Compose et traitement avec une combinaison de peptides
US5254535A (en) * 1989-04-17 1993-10-19 The Children's Hospital Of Pennsylvania Composition and treatment with biologically active peptides and antibiotic
GR1000913B (el) * 1989-05-18 1993-03-16 Magainin Sciences Inc Συνθεση & θεραπεια με βιολογικως δραστικα πεπτιδια & ορισμενα ανιοντα
WO1991000869A1 (fr) * 1989-07-07 1991-01-24 Scripps Clinic And Research Foundation Analogues de substitution des peptides de la magainine
US5912231A (en) * 1989-07-07 1999-06-15 Scripps Clinic And Research Foundation Substitution analogues of magainin peptides
EP0528861A4 (en) * 1990-04-23 1993-07-28 Magainin Sciences, Inc. Composition and treatment with biologically active peptides and toxic cations
JPH05507273A (ja) * 1990-05-14 1993-10-21 マゲイニン　サイエンセズ　インコーポレーテッド Ｄアミノ酸残基を有する生物活性ペプチドの組成物およびそれによる治療方法
CA2045073A1 (fr) * 1990-06-27 1991-12-28 Barry Berkowitz Composition et traitement a base de peptides biologiquement actifs et d'antibiotiques qui inhibent l'adn-gyrase
ATE308562T1 (de) * 1990-08-10 2005-11-15 Virtual Drug Dev Inc Antimikrobielle peptide wirksam gegen pflanzenpathogene, ihre verwendung und auf sie bezogene nachweismethoden
AU648140B2 (en) * 1991-02-01 1994-04-14 Virtual Drug Development, Inc. Reverse antimicrobial peptides and antimicrobial compositions
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
AU3512595A (en) * 1994-09-13 1996-03-29 Magainin Pharmaceuticals, Inc. Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds
CN114432428B (zh) * 2022-02-24 2024-07-23 西北农林科技大学 PGLa提高细菌对抗生素的敏感性和延缓细菌耐药性产生的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4936815A (fr) * 1972-08-18 1974-04-05
US3928306A (en) * 1973-10-23 1975-12-23 Eisai Co Ltd Peptides having xenopsin-like pharmacological activity

Also Published As

Publication number Publication date
EP0362209A4 (fr) 1990-07-03
DE3850107D1 (de) 1994-07-14
IL85587A0 (en) 1988-08-31
AU1495588A (en) 1988-09-26
EP0362209B1 (fr) 1994-06-08
CA1339387C (fr) 1997-08-26
AU609118B2 (en) 1991-04-26
US5567681A (en) 1996-10-22
ATE106896T1 (de) 1994-06-15
JPH02503083A (ja) 1990-09-27
EP0362209A1 (fr) 1990-04-11
WO1988006597A1 (fr) 1988-09-07
DE3850107T2 (de) 1995-02-23
JP2555174B2 (ja) 1996-11-20

Similar Documents

Publication Publication Date Title
IL85587A (en) Magainin polypeptides active against gram-positive and gram-negative bacteria,fungi,viruses and protozoa and a pharmaceutical composition containing the same
CS782986A2 (en) Insecticide and method of its active component preparation
GR3003937T3 (fr)
MY130047A (en) Methods and compositions employing certain lysozymes and endoglycosidases
ES2008408A6 (es) Un procedimiento para la preparacion de pirazolinas utiles como insecticidas.
NO165861C (no) Antimikrobielle preparater for fjerning av bakterier fra overflater, samt anvendelse av slike preparater.
NZ241910A (en) Biological proteins from mirabilis, their use and manufacture
SE8803071D0 (sv) Bakteriebehandling for att bevara hokvalitet genom att tillegga genius bacillus mikroorganismer
ES8800160A1 (es) Procedimiento de obtencion de acidos quinolincarboxilicos con propiedades antibacteriales.
EP0301078A4 (fr) Polypeptides presentant une activite contre les bacteries gram-positives et gram-negatives.
FI885136A0 (fi) Konserveringsmedel foer livsmedel.
HU9203550D0 (en) Shaped bodies amde of block-polymerized thermoplastic polyether and their manufacturing method
DK347788D0 (da) Teicoplaninlignende forbindelser, fremgangsmaade og mikroorganisme til fremstilling deraf og farmaceutisk praeparat indeholdende saadanne forbindelser
IL91851A0 (en) Antimicrobial compositions containing 2,2-dibromo-2-nitroethanol and methods for killing microorganisms utilizing the same
ZA884728B (en) Agent for inactivating spores and process for prolonging the storage life of products,substances or produce which can be spoiled by bacterial spore infestation
GR853154B (fr)
NZ209171A (en) Immunomodulating medicament: bacteriophagic lysate of bacteria
IL92817A0 (en) Substituted guanidine and amidine compounds,their production and fungicidal compositions containing same
ES8707955A1 (es) Un procedimiento para la preparacion pirazolidinonas biciclicas'
AR243727A1 (es) 4-alcoxi-n-(2,3-diclorofenil)benzamidas utiles como reguladores del crecimiento de las plantas.
MY103323A (en) Alpha-halopyruvate oxime
Vogel et al. Microbiologic change in oral flora during hospitalization.
UA19048A (uk) Стимулятор росту рослиh
JPS51121516A (en) Non-medical germicides
SU1088319A1 (ru) 2-Ацетилгидразино-4-(3,4-диоксифенил)-тиазол, проявляющий антимикробную активность в отношении кишечной палочки и золотистого стафилококка

Legal Events

Date Code Title Description
RH Patent void