DE3850107D1 - Neue synthetische bioaktive verbindungen und verfahren zur herstellung bioaktiver wirkungen. - Google Patents

Neue synthetische bioaktive verbindungen und verfahren zur herstellung bioaktiver wirkungen.

Info

Publication number
DE3850107D1
DE3850107D1 DE3850107T DE3850107T DE3850107D1 DE 3850107 D1 DE3850107 D1 DE 3850107D1 DE 3850107 T DE3850107 T DE 3850107T DE 3850107 T DE3850107 T DE 3850107T DE 3850107 D1 DE3850107 D1 DE 3850107D1
Authority
DE
Germany
Prior art keywords
bioactive
producing
new synthetic
effects
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3850107T
Other languages
English (en)
Other versions
DE3850107T2 (de
Inventor
Michael Zasloff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
US Department of Commerce
Original Assignee
US Department of Health and Human Services
US Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/021,493 external-priority patent/US4810777A/en
Application filed by US Department of Health and Human Services, US Department of Commerce filed Critical US Department of Health and Human Services
Publication of DE3850107D1 publication Critical patent/DE3850107D1/de
Application granted granted Critical
Publication of DE3850107T2 publication Critical patent/DE3850107T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DE3850107T 1987-03-04 1988-02-23 Neue synthetische bioaktive verbindungen und verfahren zur herstellung bioaktiver wirkungen. Expired - Fee Related DE3850107T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/021,493 US4810777A (en) 1987-03-04 1987-03-04 Antimicrobial compounds
US7673487A 1987-07-23 1987-07-23
US8179387A 1987-08-05 1987-08-05
PCT/US1988/000520 WO1988006597A1 (en) 1987-03-04 1988-02-23 New synthetic bioactive compounds and method of producing bioactive effect

Publications (2)

Publication Number Publication Date
DE3850107D1 true DE3850107D1 (de) 1994-07-14
DE3850107T2 DE3850107T2 (de) 1995-02-23

Family

ID=27361650

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3850107T Expired - Fee Related DE3850107T2 (de) 1987-03-04 1988-02-23 Neue synthetische bioaktive verbindungen und verfahren zur herstellung bioaktiver wirkungen.

Country Status (9)

Country Link
US (1) US5567681A (de)
EP (1) EP0362209B1 (de)
JP (1) JP2555174B2 (de)
AT (1) ATE106896T1 (de)
AU (1) AU609118B2 (de)
CA (1) CA1339387C (de)
DE (1) DE3850107T2 (de)
IL (1) IL85587A (de)
WO (1) WO1988006597A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266562A (en) * 1987-11-19 1993-11-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Anti-inflammatory agents
JPH03504501A (ja) * 1988-05-27 1991-10-03 マゲイニン　サイエンセス　インコーポレーテッド 両親媒性ペプチドとその用途
HUT57992A (en) * 1988-10-21 1992-01-28 Magainin Sciences Inc Process for producing composition comprising biologically active peptides and certain anions
CA2007913A1 (en) * 1989-01-30 1990-07-30 Michael Zasloff Composition and treatment with peptide combinations
US5254535A (en) * 1989-04-17 1993-10-19 The Children's Hospital Of Pennsylvania Composition and treatment with biologically active peptides and antibiotic
GR1000913B (el) * 1989-05-18 1993-03-16 Magainin Sciences Inc Συνθεση & θεραπεια με βιολογικως δραστικα πεπτιδια & ορισμενα ανιοντα
US5912231A (en) * 1989-07-07 1999-06-15 Scripps Clinic And Research Foundation Substitution analogues of magainin peptides
EP0761684A3 (de) * 1989-07-07 1997-07-02 Scripps Research Inst Alanine Substituierungsanaloge von Magaininpeptiden
JPH05509295A (ja) * 1990-04-23 1993-12-22 マゲイニン　サイエンセズ　インコーポレーテッド 生物学的に活性なペプチドおよび毒性陽イオンを有する組成物およびこれらを使用する治療法
WO1991017760A1 (en) * 1990-05-14 1991-11-28 Magainin Sciences Inc. Composition of and treatment with biologically active peptides having d-amino acid residues
EP0559647A1 (de) * 1990-06-27 1993-09-15 Magainin Pharmaceuticals Inc. Zusammensetzung und behandlung mit biologisch aktiven peptiden und antibiotika, welche die dna-gyrase inhibieren
JPH07242696A (ja) * 1990-08-10 1995-09-19 Enichem Partecipazioni Spa 植物病原体に対して活性な抗菌性ペプチド、その使用法およびこれに関連するスクリーニング法
AU648140B2 (en) * 1991-02-01 1994-04-14 Virtual Drug Development, Inc. Reverse antimicrobial peptides and antimicrobial compositions
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
AU3512595A (en) * 1994-09-13 1996-03-29 Magainin Pharmaceuticals, Inc. Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds
CN114432428A (zh) * 2022-02-24 2022-05-06 西北农林科技大学 PGLa提高细菌对抗生素的敏感性和延缓细菌耐药性产生的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4936815A (de) * 1972-08-18 1974-04-05
US3928306A (en) * 1973-10-23 1975-12-23 Eisai Co Ltd Peptides having xenopsin-like pharmacological activity

Also Published As

Publication number Publication date
CA1339387C (en) 1997-08-26
ATE106896T1 (de) 1994-06-15
JPH02503083A (ja) 1990-09-27
IL85587A (en) 1992-09-06
IL85587A0 (en) 1988-08-31
EP0362209B1 (de) 1994-06-08
DE3850107T2 (de) 1995-02-23
US5567681A (en) 1996-10-22
EP0362209A4 (de) 1990-07-03
AU1495588A (en) 1988-09-26
WO1988006597A1 (en) 1988-09-07
JP2555174B2 (ja) 1996-11-20
AU609118B2 (en) 1991-04-26
EP0362209A1 (de) 1990-04-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee