IL84985A - Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography - Google Patents

Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography

Info

Publication number
IL84985A
IL84985A IL84985A IL8498587A IL84985A IL 84985 A IL84985 A IL 84985A IL 84985 A IL84985 A IL 84985A IL 8498587 A IL8498587 A IL 8498587A IL 84985 A IL84985 A IL 84985A
Authority
IL
Israel
Prior art keywords
couplers
life
carbonyl group
acid derivatives
affinity chromatography
Prior art date
Application number
IL84985A
Other languages
English (en)
Other versions
IL84985A0 (en
Original Assignee
Kanto Ishi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanto Ishi Pharma Co Ltd filed Critical Kanto Ishi Pharma Co Ltd
Publication of IL84985A0 publication Critical patent/IL84985A0/xx
Priority to IL101426A priority Critical patent/IL101426A0/xx
Publication of IL84985A publication Critical patent/IL84985A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IL84985A 1986-12-29 1987-12-29 Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography IL84985A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL101426A IL101426A0 (en) 1986-12-29 1992-03-31 Amino-coupled sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31018186 1986-12-29
JP62295641A JPS63264493A (ja) 1986-12-29 1987-11-24 活性カルボニル基を持つシアル酸誘導体

Publications (2)

Publication Number Publication Date
IL84985A0 IL84985A0 (en) 1988-06-30
IL84985A true IL84985A (en) 1993-02-21

Family

ID=26560346

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84985A IL84985A (en) 1986-12-29 1987-12-29 Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography

Country Status (11)

Country Link
US (2) US4918177A (de)
EP (1) EP0273388A3 (de)
JP (1) JPS63264493A (de)
KR (1) KR950007923B1 (de)
CN (1) CN87108160A (de)
AU (1) AU606909B2 (de)
DK (1) DK682287A (de)
FI (1) FI875738A (de)
IL (1) IL84985A (de)
NO (1) NO166792C (de)
NZ (1) NZ223043A (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63264493A (ja) * 1986-12-29 1988-11-01 Mect Corp 活性カルボニル基を持つシアル酸誘導体
US5034516A (en) * 1987-08-04 1991-07-23 University Of Ottawa Synthetic antigens of sialic acid and derivatives thereof
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
US5344870A (en) * 1987-12-02 1994-09-06 Alberta Research Council Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
JPH01228997A (ja) * 1988-03-10 1989-09-12 Mect Corp シアロシルグリセライド類及びその製造方法
US5177062A (en) * 1988-08-09 1993-01-05 Mect Corporation Method for treating immune complex diseases with n-acetylneuraminic acid
JPH02145596A (ja) * 1988-11-29 1990-06-05 Mect Corp 活性エステル基を持つシタル酸誘導体
WO1991013079A1 (fr) 1990-02-27 1991-09-05 Drug Delivery System Institute, Ltd. Derive de glycolipide contenant de l'acide sialique
US5212075A (en) * 1991-04-15 1993-05-18 The Regents Of The University Of California Compositions and methods for introducing effectors to pathogens and cells
US5310682A (en) * 1992-06-17 1994-05-10 Indiana University Foundation Fluorogenic reagents for detection of glycoconjugates, α-ketoacids and diketones
US5783564A (en) * 1993-12-24 1998-07-21 Mitsubishi Chemical Corporation Sialic acid derivatives
TW479061B (en) * 1993-12-24 2002-03-11 Mitsubishi Chem Corp Sialic acid derivatives
JP3648740B2 (ja) * 1994-05-27 2005-05-18 ダイキン工業株式会社 ７位をフッ素で置換した２，３−ジデヒドロシアル酸およびその合成中間体
EP0957107B1 (de) 1996-05-16 2004-07-21 Nissin Food Products Co., Ltd. Verbindungen mit antiviraler aktivität
JP4544663B2 (ja) * 1999-06-21 2010-09-15 生化学工業株式会社 デアミノノイラミン酸誘導体、デアミノノイラミニダーゼの精製方法及びデアミノノイラミン酸結合性物質の検出方法
ES2735809T3 (es) * 2003-08-12 2019-12-20 Lipoxen Tech Limited Derivativos del ácido siálico para la derivatización y conjugación de proteínas
CN101039965A (zh) * 2004-08-12 2007-09-19 利普生技术有限公司 唾液酸衍生物
US7875708B2 (en) 2004-08-12 2011-01-25 Lipoxen Technologies Limited Sialic acid derivatives
WO2006090119A1 (en) * 2005-02-23 2006-08-31 Lipoxen Technologies Limited Activated sialic acid derivatives for protein derivatisation and conjugation
US9119866B2 (en) * 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
GB201201411D0 (en) * 2012-01-26 2012-03-14 Thermotech Fabrics Ltd Antiviral article

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1203532A (en) * 1980-07-10 1986-04-22 Chembiomed Ltd. Synthesis of tumor antigenic determinant
JPS59164798A (ja) * 1983-03-09 1984-09-17 Rikagaku Kenkyusho シアル酸含有糖脂質誘導体
JPS6344590A (ja) * 1986-08-12 1988-02-25 Mect Corp シアル酸誘導体の製造方法
JPS63264493A (ja) * 1986-12-29 1988-11-01 Mect Corp 活性カルボニル基を持つシアル酸誘導体
JPH01125394A (ja) * 1987-11-10 1989-05-17 Mect Corp シアロシルグリセロリピッド類及びその製造方法
JPH01228997A (ja) * 1988-03-10 1989-09-12 Mect Corp シアロシルグリセライド類及びその製造方法

Also Published As

Publication number Publication date
NO166792C (no) 1991-09-04
NO875432D0 (no) 1987-12-23
EP0273388A2 (de) 1988-07-06
US4918177A (en) 1990-04-17
JPS63264493A (ja) 1988-11-01
EP0273388A3 (de) 1989-04-26
CN87108160A (zh) 1988-09-14
NO875432L (no) 1988-06-30
AU8305587A (en) 1988-06-30
KR880007570A (ko) 1988-08-27
FI875738A (fi) 1988-06-30
DK682287D0 (da) 1987-12-22
AU606909B2 (en) 1991-02-21
NO166792B (no) 1991-05-27
KR950007923B1 (ko) 1995-07-21
USRE34091E (en) 1992-10-06
IL84985A0 (en) 1988-06-30
DK682287A (da) 1988-06-30
NZ223043A (en) 1990-06-26
FI875738A0 (fi) 1987-12-28

Similar Documents

Publication Publication Date Title
IL84985A (en) Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography
IT1205357B (it) Composizione additiva per detergenti dotata di attivita' candeggiante e procedimento di preparazione
AU588968B2 (en) Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same
HU906721D0 (en) Methylene-diphosphonic acid derivatives and inflammation-preventing preparations containing them as active agents
EP0258494A3 (en) Modified bnc connector for active probe
ZA866809B (en) Process for the preparation of optically active alpha-phenoxy-propionic acid and its derivatives
HUT43848A (en) Process for producing pyridinyl-piperazine derivatives and pharmaceutical compositions containing them as active agents
ZA891534B (en) Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof
HU908400D0 (en) Process for the production of imidazo(4,5-c)pyridine derivatives and medical preparations containing these compounds as active agents
HUT41757A (en) Process for producing pharmaceutical compositions containing e-desmethyl-mevalonic acid derivatives and process for producing the active agents
HUT42691A (en) Process for preparing carboxylic acid ester derivatives and insecticidal preparations containing the same as active substance
IL101426A0 (en) Amino-coupled sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography
AU5541886A (en) Method of administering ethanolamine derivatives to livestock
GB2157283B (en) Esters of 3,5-diacetylamino-2,4,6-triiodobenzoic acid as x-ray contrast agents
IL81457A0 (en) Preparation of carboxylic acid amides
GB8800193D0 (en) Preparation & biological activity of aminoxyalkyl-phosphonous-phosphinic & phosphonic acid derivatives
HU908440D0 (en) Herbicide preparations containing calicylic acid derivatives and process for the production of the active agents
OA09419A (fr) Dérivés de l'acide 3-pyrrolidinylthio-1-azabicyclo (3.2.0.) -hept-2-ene-2-carboxylique et leur préparation.
CS8703287A1 (en) Method of 2-benzothiazolsulphenic acid's sulphenamides preparation
HUT42463A (en) Herbicide compositions containing thiazolyl-amide derivatives as active agents and process for producing thiazolyl-amide derivatives
IL86548A0 (en) Preparation of piperidinylcyclopentylheptenoic acid derivatives
IL92279A0 (en) Preparation of 2-chloro-4-toluenesulfonic acid
IT1200460B (it) Composizioni di farmaci dotae di attivita' antimicrobica e procedimento per la loro preparazione
EP0258815A3 (en) Derivatives of 2,2-dimethyl-cyclopropanecarboxylic acid derivatives of 2,2-dimethyl-cyclopropanecarboxylic acid
GB8717997D0 (en) Derivatives of benzoyloxyacetic acid