IL84985A - Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography - Google Patents

Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography

Info

Publication number
IL84985A
IL84985A IL84985A IL8498587A IL84985A IL 84985 A IL84985 A IL 84985A IL 84985 A IL84985 A IL 84985A IL 8498587 A IL8498587 A IL 8498587A IL 84985 A IL84985 A IL 84985A
Authority
IL
Israel
Prior art keywords
couplers
life
carbonyl group
acid derivatives
affinity chromatography
Prior art date
Application number
IL84985A
Other languages
English (en)
Other versions
IL84985A0 (en
Original Assignee
Kanto Ishi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanto Ishi Pharma Co Ltd filed Critical Kanto Ishi Pharma Co Ltd
Publication of IL84985A0 publication Critical patent/IL84985A0/xx
Priority to IL101426A priority Critical patent/IL101426A0/xx
Publication of IL84985A publication Critical patent/IL84985A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL84985A 1986-12-29 1987-12-29 Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography IL84985A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL101426A IL101426A0 (en) 1986-12-29 1992-03-31 Amino-coupled sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31018186 1986-12-29
JP62295641A JPS63264493A (ja) 1986-12-29 1987-11-24 活性カルボニル基を持つシアル酸誘導体

Publications (2)

Publication Number Publication Date
IL84985A0 IL84985A0 (en) 1988-06-30
IL84985A true IL84985A (en) 1993-02-21

Family

ID=26560346

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84985A IL84985A (en) 1986-12-29 1987-12-29 Sialic acid derivatives with an active carbonyl group useful for extending biological half-life of physiological agents and as couplers for affinity chromatography

Country Status (11)

Country Link
US (2) US4918177A (de)
EP (1) EP0273388A3 (de)
JP (1) JPS63264493A (de)
KR (1) KR950007923B1 (de)
CN (1) CN87108160A (de)
AU (1) AU606909B2 (de)
DK (1) DK682287A (de)
FI (1) FI875738A (de)
IL (1) IL84985A (de)
NO (1) NO166792C (de)
NZ (1) NZ223043A (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63264493A (ja) * 1986-12-29 1988-11-01 Mect Corp 活性カルボニル基を持つシアル酸誘導体
US5034516A (en) * 1987-08-04 1991-07-23 University Of Ottawa Synthetic antigens of sialic acid and derivatives thereof
US5344870A (en) * 1987-12-02 1994-09-06 Alberta Research Council Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
JPH01228997A (ja) * 1988-03-10 1989-09-12 Mect Corp シアロシルグリセライド類及びその製造方法
US5177062A (en) * 1988-08-09 1993-01-05 Mect Corporation Method for treating immune complex diseases with n-acetylneuraminic acid
JPH02145596A (ja) * 1988-11-29 1990-06-05 Mect Corp 活性エステル基を持つシタル酸誘導体
US5243035A (en) * 1990-02-27 1993-09-07 Drug Delivery System Institute, Ltd. Sialic acid-containing glycolipid derivatives
US5212075A (en) * 1991-04-15 1993-05-18 The Regents Of The University Of California Compositions and methods for introducing effectors to pathogens and cells
US5310682A (en) * 1992-06-17 1994-05-10 Indiana University Foundation Fluorogenic reagents for detection of glycoconjugates, α-ketoacids and diketones
US5783564A (en) * 1993-12-24 1998-07-21 Mitsubishi Chemical Corporation Sialic acid derivatives
TW479061B (en) * 1993-12-24 2002-03-11 Mitsubishi Chem Corp Sialic acid derivatives
CN1065241C (zh) * 1994-05-27 2001-05-02 大金工业株式会社 在7位上用氟取代的2,3－二脱氢唾液酸及其合成中间体
US6337390B1 (en) 1996-05-16 2002-01-08 Nissan Food Products Co., Ltd. Compounds comprising sulfated nonulonic acid having antiviral activity
JP4544663B2 (ja) * 1999-06-21 2010-09-15 生化学工業株式会社 デアミノノイラミン酸誘導体、デアミノノイラミニダーゼの精製方法及びデアミノノイラミン酸結合性物質の検出方法
WO2005016949A2 (en) * 2003-08-12 2005-02-24 Lipoxen Technologies Limited Sialic acid derivatives
CN101039965A (zh) * 2004-08-12 2007-09-19 利普生技术有限公司 唾液酸衍生物
EP1776389B1 (de) 2004-08-12 2016-06-29 Lipoxen Technologies Limited Sialinsäurederivate
EP1853634B1 (de) * 2005-02-23 2016-08-10 Lipoxen Technologies Limited Aktivierte sialinsäurederivate für die derivatisierung und konjugation von proteinen
US9119866B2 (en) 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
GB201201411D0 (en) * 2012-01-26 2012-03-14 Thermotech Fabrics Ltd Antiviral article

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1203532A (en) * 1980-07-10 1986-04-22 Chembiomed Ltd. Synthesis of tumor antigenic determinant
JPS59164798A (ja) * 1983-03-09 1984-09-17 Rikagaku Kenkyusho シアル酸含有糖脂質誘導体
JPS6344590A (ja) * 1986-08-12 1988-02-25 Mect Corp シアル酸誘導体の製造方法
JPS63264493A (ja) * 1986-12-29 1988-11-01 Mect Corp 活性カルボニル基を持つシアル酸誘導体
JPH01125394A (ja) * 1987-11-10 1989-05-17 Mect Corp シアロシルグリセロリピッド類及びその製造方法
JPH01228997A (ja) * 1988-03-10 1989-09-12 Mect Corp シアロシルグリセライド類及びその製造方法

Also Published As

Publication number Publication date
CN87108160A (zh) 1988-09-14
NZ223043A (en) 1990-06-26
FI875738A0 (fi) 1987-12-28
USRE34091E (en) 1992-10-06
NO166792B (no) 1991-05-27
AU8305587A (en) 1988-06-30
EP0273388A2 (de) 1988-07-06
FI875738A (fi) 1988-06-30
DK682287D0 (da) 1987-12-22
US4918177A (en) 1990-04-17
NO875432L (no) 1988-06-30
AU606909B2 (en) 1991-02-21
DK682287A (da) 1988-06-30
JPS63264493A (ja) 1988-11-01
EP0273388A3 (de) 1989-04-26
KR880007570A (ko) 1988-08-27
NO166792C (no) 1991-09-04
KR950007923B1 (ko) 1995-07-21
IL84985A0 (en) 1988-06-30
NO875432D0 (no) 1987-12-23

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