US5084266A
(en)
*
|
1988-02-03 |
1992-01-28 |
The University Of Melbourne |
Method for tumor imaging utilizing a labelled tumor specific antibody and a non-tumor reactive antibody
|
CA1329119C
(en)
*
|
1988-03-29 |
1994-05-03 |
Milton David Goldenberg |
Cytotoxic therapy
|
CA1339415C
(en)
*
|
1989-08-24 |
1997-09-02 |
Milton David Goldenberg |
Detection and treatment of infections with immunoconjugates
|
DK176290D0
(da)
*
|
1990-07-24 |
1990-07-24 |
Novo Nordisk As |
Terapeutisk og diagnostisk praeparat
|
US5398685A
(en)
*
|
1992-01-10 |
1995-03-21 |
Wilk; Peter J. |
Endoscopic diagnostic system and associated method
|
EP0643583B1
(de)
*
|
1992-05-06 |
2000-07-26 |
Immunomedics, Inc. |
Intraoperative, intravaskulare und endoskopische bestimmung und behandlung von verletzungen und tumoren
|
US6096289A
(en)
*
|
1992-05-06 |
2000-08-01 |
Immunomedics, Inc. |
Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
|
US5590656A
(en)
*
|
1992-09-15 |
1997-01-07 |
The Ohio State University Research Foundation |
Application of peptide/cell receptor kinetics utilizing radiolabeled somatostatin congeners in the in situ, in vivo detection and differentiation of neoplastic tissue
|
US5441050A
(en)
*
|
1992-12-18 |
1995-08-15 |
Neoprobe Corporation |
Radiation responsive surgical instrument
|
US5482698A
(en)
*
|
1993-04-22 |
1996-01-09 |
Immunomedics, Inc. |
Detection and therapy of lesions with biotin/avidin polymer conjugates
|
US5657759A
(en)
*
|
1993-05-13 |
1997-08-19 |
Synectics Medical, Incorporated |
Measurement of gastric emptying and gastrointestinal output
|
US6120768A
(en)
*
|
1993-05-17 |
2000-09-19 |
Immunomedics, Inc. |
Dota-biotin derivatives
|
CA2163107C
(en)
*
|
1993-05-17 |
2001-04-17 |
David Milton Goldenberg |
Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates
|
AU1937195A
(en)
*
|
1994-03-02 |
1995-09-18 |
Mark Krakovitz |
Hybrid probes for characterizing diseases
|
US5482040A
(en)
*
|
1994-04-14 |
1996-01-09 |
The Ohio State University Research Foundation |
Biostaging of adenocarcinomas utilizing radiolabeled tumor-associated glycoprotein antibodies
|
US5746996A
(en)
*
|
1994-06-03 |
1998-05-05 |
Immunomedics, Inc. |
Thiolation of peptides for radionuclide-based radiodetection and radiotherapy
|
US5608520A
(en)
*
|
1994-07-11 |
1997-03-04 |
The United States Of America As Represented By He Department Of Energy |
Plasma emission spectroscopy method of tumor therapy
|
US5813985A
(en)
*
|
1995-07-31 |
1998-09-29 |
Care Wise Medical Products Corporation |
Apparatus and methods for providing attenuation guidance and tumor targeting for external beam radiation therapy administration
|
AU9661598A
(en)
*
|
1997-09-10 |
1999-03-29 |
Yale University |
Radiation dosimetry with magnetic resonance detectable compounds
|
US6207111B1
(en)
*
|
1997-12-31 |
2001-03-27 |
Pem Technologies, Inc. |
System for describing the physical distribution of an agent in a patient
|
ATE473242T1
(de)
|
1998-05-20 |
2010-07-15 |
Immunomedics Inc |
Therapeutische mittel welche einen bispezifischen anti-hla class ii invariant chain x anti-pathogen antikörper enthalten
|
US6242741B1
(en)
*
|
1998-10-23 |
2001-06-05 |
United States Surgical Corporation |
Radiation detection apparatus
|
WO2000059547A2
(en)
*
|
1999-04-02 |
2000-10-12 |
Center For Molecular Medicine And Immunology |
Method of detecting endometriosis
|
US6167297A
(en)
*
|
1999-05-05 |
2000-12-26 |
Benaron; David A. |
Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
|
US8383081B2
(en)
*
|
1999-05-10 |
2013-02-26 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods of use
|
US7829064B2
(en)
*
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
US8119101B2
(en)
*
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
US7373197B2
(en)
*
|
2000-03-03 |
2008-05-13 |
Intramedical Imaging, Llc |
Methods and devices to expand applications of intraoperative radiation probes
|
US6602488B1
(en)
|
2000-03-03 |
2003-08-05 |
Intramedical Imaging, Llc |
Use of radiopharmaceuticals and intraoperative radiation probe for delivery of medicinal treatments
|
US6510336B1
(en)
|
2000-03-03 |
2003-01-21 |
Intra Medical Imaging, Llc |
Methods and devices to expand applications of intraoperative radiation probes
|
US7008633B2
(en)
*
|
2000-12-18 |
2006-03-07 |
Board Of Regents, The University Of Texas System |
Local regional chemotherapy and radiotherapy using in situ hydrogel
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
AU2002303181A1
(en)
*
|
2001-03-30 |
2002-10-15 |
University Of Massachusetts |
Morpholino imaging and therapy
|
US6993376B2
(en)
*
|
2002-01-28 |
2006-01-31 |
Testardi Louis R |
Radiation measurement within the human body
|
US9770517B2
(en)
|
2002-03-01 |
2017-09-26 |
Immunomedics, Inc. |
Anti-Trop-2 antibody-drug conjugates and uses thereof
|
US7939304B2
(en)
*
|
2002-10-02 |
2011-05-10 |
Catalyst Biosciences, Inc. |
Mutant MT-SP1 proteases with altered substrate specificity or activity
|
US20060024289A1
(en)
*
|
2002-10-02 |
2006-02-02 |
Ruggles Sandra W |
Cleavage of VEGF and VEGF receptor by wild-type and mutant proteases
|
WO2004039233A2
(en)
*
|
2002-10-31 |
2004-05-13 |
Given Imaging Ltd. |
System and method for in vivo detection of h. pylori
|
US8420086B2
(en)
|
2002-12-13 |
2013-04-16 |
Immunomedics, Inc. |
Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases
|
EP1660519B1
(de)
*
|
2003-07-29 |
2014-05-14 |
Immunomedics, Inc. |
Konjugate von 2-[18F]Fluor-2-desoxy-D-glucose und einem Peptid-Molekül
|
AU2004263538B2
(en)
*
|
2003-08-08 |
2009-09-17 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
DE602004025726D1
(de)
*
|
2003-11-14 |
2010-04-08 |
Genvec Inc |
Pharmazeutische verbindung zur behandlung von lokal fortgeschrittenem primär inoperablen pankreaskarzinom (lapc).
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
US8883160B2
(en)
*
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
EP1733056B1
(de)
|
2004-03-31 |
2013-05-22 |
The General Hospital Corporation |
Verfahren zur bestimmung des ansprechens eines tumors auf behandlungen mit dem epidermalen wachstumsfaktor-rezeptor als target
|
CA2562729C
(en)
|
2004-04-12 |
2013-11-12 |
Sandra Waugh Ruggles |
Cleavage of vegf and vegf receptor by wildtype and mutant mt-sp1
|
US7829291B2
(en)
*
|
2005-02-17 |
2010-11-09 |
Vanderbilt University |
In situ analysis of tissues
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
JP5214252B2
(ja)
|
2005-03-03 |
2013-06-19 |
イミューノメディクス、インコーポレイテッド |
ヒト化l243抗体
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
US8475794B2
(en)
|
2005-04-06 |
2013-07-02 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
PT2298815E
(pt)
|
2005-07-25 |
2015-07-16 |
Emergent Product Dev Seattle |
Moléculas de ligaçao especificas para cd37 e especificas para cd20
|
EP2674440B1
(de)
|
2005-12-16 |
2019-07-03 |
IBC Pharmaceuticals, Inc. |
Polyvalente bioaktive anordnungen auf immunglobulinbasis
|
MX2008015524A
(es)
*
|
2006-06-12 |
2009-01-13 |
Trubion Pharmaceuticals Inc |
Proteinas de union multivalentes monocatenarias con funcion efectora.
|
KR101476458B1
(ko)
|
2006-07-05 |
2015-01-05 |
카탈리스트 바이오사이언시즈, 인코포레이티드 |
프로테아제 스크리닝 방법 및 이에 의해 확인된 프로테아제
|
BRPI0814060A2
(pt)
*
|
2007-07-06 |
2015-01-06 |
Trubion Pharmaceuticals Inc |
Peptídeos ligantes tendo um domínio de ligação específico disposto em c-terminal
|
AU2008302345A1
(en)
*
|
2007-09-19 |
2009-03-26 |
Oncofluor, Inc. |
Method for imaging and treating organs and tissues
|
WO2009126944A1
(en)
|
2008-04-11 |
2009-10-15 |
Trubion Pharmaceuticals, Inc. |
Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
US9605844B2
(en)
*
|
2009-09-01 |
2017-03-28 |
Cree, Inc. |
Lighting device with heat dissipation elements
|
WO2011085354A1
(en)
*
|
2010-01-11 |
2011-07-14 |
Center For Molecular Medicine And Immunology |
Enhanced cytotoxicity of anti-cd74 and anti-hla-dr antibodies with interferon-gamma
|
US9757458B2
(en)
|
2011-12-05 |
2017-09-12 |
Immunomedics, Inc. |
Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells
|
EP2788020A4
(de)
|
2011-12-05 |
2015-04-29 |
Immunomedics Inc |
Therapeutische verwendung von anti-cd22-antikörpern zur induktion von trogozytose
|
US10517483B2
(en)
|
2012-12-05 |
2019-12-31 |
Accuvein, Inc. |
System for detecting fluorescence and projecting a representative image
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
US9931417B2
(en)
|
2012-12-13 |
2018-04-03 |
Immunomedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
US10206918B2
(en)
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
PL2900277T3
(pl)
|
2012-12-13 |
2022-05-16 |
Immunomedics, Inc. |
Dawkowanie immunokoniugatów przeciwciał i sn-38 dla poprawy skuteczności i zmniejszenia toksyczności
|
WO2015012904A2
(en)
|
2012-12-13 |
2015-01-29 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
EP3268362B1
(de)
|
2015-03-11 |
2021-10-20 |
Peloton Therapeutics, Inc. |
Substituierte pyridine und verwendungen davon
|
JP6746845B2
(ja)
|
2015-04-22 |
2020-08-26 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
循環trop−2陽性癌細胞の単離、検出、診断及び/または特徴付け
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
MY197562A
(en)
|
2015-09-21 |
2023-06-23 |
Aptevo Res & Development Llc |
Cd3 binding polypeptides
|
CA3002381A1
(en)
|
2015-10-21 |
2017-04-27 |
Teclison Limited |
Compositions and methods for immune-mediated cancer therapy
|
CN108601841A
(zh)
|
2016-02-10 |
2018-09-28 |
免疫医疗公司 |
Abcg2抑制剂与sacituzumab govitecan(immu-132)的组合克服表达trop-2的癌中对sn-38的抗性
|
EP3448260A4
(de)
|
2016-04-27 |
2019-10-09 |
Immunomedics, Inc. |
Wirksamkeit von anti-trop-2-sn-38-antikörper-wirkstoff-konjugaten zur therapie von rezidivierten/refraktären tumoren gegen checkpoint-inhibitoren
|
EP3600283A4
(de)
|
2017-03-27 |
2020-12-16 |
Immunomedics, Inc. |
Behandlung von trop-2-exprimierendem triple-negativem brustkrebs mit sacituzumab govitecan und einem rad51-hemmer
|
WO2018187074A1
(en)
|
2017-04-03 |
2018-10-11 |
Immunomedics, Inc. |
Subcutaneous administration of antibody-drug conjugates for cancer therapy
|
EP3810109A4
(de)
|
2018-05-31 |
2022-03-16 |
Peloton Therapeutics, Inc. |
Zusammensetzungen und verfahren zur hemmung von cd73
|
JP7425794B2
(ja)
|
2018-10-30 |
2024-01-31 |
ペロトン セラピューティクス, インコーポレイテッド |
置換されたインダンを含む固体分散体及び医薬組成物並びにそれの製造方法及び使用
|
US11625825B2
(en)
|
2019-01-30 |
2023-04-11 |
Covidien Lp |
Method for displaying tumor location within endoscopic images
|
JP2023512214A
(ja)
|
2020-01-28 |
2023-03-24 |
リフレクション メディカル, インコーポレイテッド |
放射性核種および外部ビーム放射線療法の共同最適化
|
BR112022023199A2
(pt)
|
2020-05-15 |
2023-04-04 |
Algen Biotechnologies Inc |
Certas composições químicas e métodos de uso das mesmas
|