IL84589A0 - Pyrrolobenzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents
Pyrrolobenzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- IL84589A0 IL84589A0 IL84589A IL8458987A IL84589A0 IL 84589 A0 IL84589 A0 IL 84589A0 IL 84589 A IL84589 A IL 84589A IL 8458987 A IL8458987 A IL 8458987A IL 84589 A0 IL84589 A0 IL 84589A0
- Authority
- IL
- Israel
- Prior art keywords
- pyrrolobenzimidazoles
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863642315 DE3642315A1 (de) | 1986-12-11 | 1986-12-11 | Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL84589A0 true IL84589A0 (en) | 1988-04-29 |
Family
ID=6315954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL84589A IL84589A0 (en) | 1986-12-11 | 1987-11-25 | Pyrrolobenzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing them |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4863945A (pt) |
| EP (1) | EP0271040A3 (pt) |
| JP (1) | JPS63162692A (pt) |
| KR (1) | KR880007536A (pt) |
| AU (1) | AU8245087A (pt) |
| DD (1) | DD267047A5 (pt) |
| DE (1) | DE3642315A1 (pt) |
| DK (1) | DK650187A (pt) |
| FI (1) | FI875438A7 (pt) |
| HU (1) | HU200339B (pt) |
| IL (1) | IL84589A0 (pt) |
| PT (1) | PT86331B (pt) |
| ZA (1) | ZA879166B (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5206240A (en) * | 1989-12-08 | 1993-04-27 | Merck & Co., Inc. | Nitrogen-containing spirocycles |
| DE4027592A1 (de) * | 1990-08-31 | 1992-03-05 | Beiersdorf Ag | Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
| US5434163A (en) * | 1993-05-14 | 1995-07-18 | The Medical College Of Pennsylvania | Treatment of Cryptococcus neoformans infection |
| US6184226B1 (en) | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| US6878714B2 (en) * | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| EP1598353A1 (en) * | 2004-05-17 | 2005-11-23 | Boehringer Ingelheim International GmbH | Pyrrolobenzimidazolones and their use as antiproliferative agents |
| US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
| US20060142247A1 (en) * | 2004-12-17 | 2006-06-29 | Guy Georges | Tricyclic heterocycles |
| CN101160312A (zh) * | 2005-04-14 | 2008-04-09 | 霍夫曼-拉罗奇有限公司 | 三环吡咯衍生物、它们的制备和作为药剂的应用 |
| WO2006108489A1 (en) * | 2005-04-14 | 2006-10-19 | F. Hoffmann-La Roche Ag | Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents |
| EP1966213A1 (en) * | 2005-12-15 | 2008-09-10 | F.Hoffmann-La Roche Ag | Tricyclic lactam derivatives, their manufacture and use as pharmaceutical agents |
| WO2007107346A1 (en) * | 2006-03-23 | 2007-09-27 | F. Hoffmann-La Roche Ag | Substituted indazole derivatives, their manufacture and use as pharmaceutical agents |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| EP2170830B1 (en) * | 2007-07-17 | 2014-10-15 | Plexxikon, Inc. | 2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS |
| KR20170058465A (ko) | 2009-04-03 | 2017-05-26 | 에프. 호프만-라 로슈 아게 | 프로판-１-술폰산 ｛３-［５-（４-클로로-페닐）-１Ｈ-피롤로［２，３-ｂ］피리딘-３-카르보닐］-２，４-디플루오로-페닐｝-아미드 조성물 및 그의 용도 |
| US8329724B2 (en) | 2009-08-03 | 2012-12-11 | Hoffmann-La Roche Inc. | Process for the manufacture of pharmaceutically active compounds |
| AU2010315126B2 (en) | 2009-11-06 | 2015-06-25 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
| WO2012109075A1 (en) | 2011-02-07 | 2012-08-16 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR851085B (pt) * | 1984-05-12 | 1985-11-25 | Boehringer Mannheim Gmbh | |
| DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3501497A1 (de) * | 1985-01-18 | 1986-07-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1986
- 1986-12-11 DE DE19863642315 patent/DE3642315A1/de not_active Withdrawn
-
1987
- 1987-11-25 IL IL84589A patent/IL84589A0/xx unknown
- 1987-12-07 ZA ZA879166A patent/ZA879166B/xx unknown
- 1987-12-07 EP EP87118046A patent/EP0271040A3/de not_active Withdrawn
- 1987-12-07 DD DD87310045A patent/DD267047A5/de not_active IP Right Cessation
- 1987-12-09 JP JP62309792A patent/JPS63162692A/ja active Pending
- 1987-12-10 DK DK650187A patent/DK650187A/da not_active Application Discontinuation
- 1987-12-10 HU HU875579A patent/HU200339B/hu not_active IP Right Cessation
- 1987-12-10 US US07/131,367 patent/US4863945A/en not_active Expired - Fee Related
- 1987-12-10 FI FI875438A patent/FI875438A7/fi not_active Application Discontinuation
- 1987-12-10 PT PT86331A patent/PT86331B/pt not_active IP Right Cessation
- 1987-12-11 KR KR870014131A patent/KR880007536A/ko not_active Withdrawn
- 1987-12-11 AU AU82450/87A patent/AU8245087A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT86331A (de) | 1988-01-01 |
| EP0271040A2 (de) | 1988-06-15 |
| HU200339B (en) | 1990-05-28 |
| DD267047A5 (de) | 1989-04-19 |
| AU8245087A (en) | 1988-06-16 |
| KR880007536A (ko) | 1988-08-27 |
| DK650187D0 (da) | 1987-12-10 |
| US4863945A (en) | 1989-09-05 |
| PT86331B (pt) | 1990-11-07 |
| FI875438A7 (fi) | 1988-06-12 |
| DE3642315A1 (de) | 1988-06-23 |
| ZA879166B (en) | 1988-06-14 |
| JPS63162692A (ja) | 1988-07-06 |
| HUT47278A (en) | 1989-02-28 |
| FI875438A0 (fi) | 1987-12-10 |
| DK650187A (da) | 1988-06-12 |
| EP0271040A3 (de) | 1989-11-02 |
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