IL82205A - Substituted alkane-sulfonamidophenyl derivatives and pharmaceutical compositions containing them - Google Patents

Substituted alkane-sulfonamidophenyl derivatives and pharmaceutical compositions containing them

Info

Publication number
IL82205A
IL82205A IL82205A IL8220587A IL82205A IL 82205 A IL82205 A IL 82205A IL 82205 A IL82205 A IL 82205A IL 8220587 A IL8220587 A IL 8220587A IL 82205 A IL82205 A IL 82205A
Authority
IL
Israel
Prior art keywords
sulfonamidophenyl
derivatives
pharmaceutical compositions
compositions containing
substituted alkane
Prior art date
Application number
IL82205A
Other languages
English (en)
Other versions
IL82205A0 (en
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of IL82205A0 publication Critical patent/IL82205A0/xx
Publication of IL82205A publication Critical patent/IL82205A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
IL82205A 1986-04-16 1987-04-13 Substituted alkane-sulfonamidophenyl derivatives and pharmaceutical compositions containing them IL82205A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868609331A GB8609331D0 (en) 1986-04-16 1986-04-16 Anti-arrythmia agents

Publications (2)

Publication Number Publication Date
IL82205A0 IL82205A0 (en) 1987-10-30
IL82205A true IL82205A (en) 1991-05-12

Family

ID=10596325

Family Applications (1)

Application Number Title Priority Date Filing Date
IL82205A IL82205A (en) 1986-04-16 1987-04-13 Substituted alkane-sulfonamidophenyl derivatives and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (3) US4863948A (fr)
EP (1) EP0242173A1 (fr)
JP (1) JPS62255474A (fr)
KR (1) KR870010012A (fr)
AU (1) AU575745B2 (fr)
CA (1) CA1295616C (fr)
DK (1) DK195087A (fr)
FI (1) FI871635A (fr)
GB (1) GB8609331D0 (fr)
HU (1) HU198014B (fr)
IL (1) IL82205A (fr)
NZ (1) NZ219990A (fr)
PT (1) PT84675B (fr)
ZA (1) ZA872703B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8609331D0 (en) * 1986-04-16 1986-05-21 Pfizer Ltd Anti-arrythmia agents
US4956382A (en) * 1987-02-07 1990-09-11 Pfizer Inc. Sulfonamide anti-arrhythmic agents
US5217970A (en) * 1989-06-26 1993-06-08 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
US5262413A (en) * 1989-06-26 1993-11-16 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
GB9021056D0 (en) * 1990-09-27 1990-11-07 Pfizer Ltd Antiarrhythmic agents
FR2674524B1 (fr) * 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5198443A (en) * 1991-06-28 1993-03-30 Warner-Lambert Company Substituted 1,2,3,6-tetrahydropyridines as central nervous system agents
KR960007566A (ko) * 1994-08-19 1996-03-22 김정규 신규한 퀴놀릴아민 유도체, 그의 제조방법 및 항부정맥제로서의 용도
WO1997046532A1 (fr) * 1996-06-03 1997-12-11 Boehringer Ingelheim Pharmaceuticals, Inc. 2-benzyl-4-sulfonyl-4h-isoquinoline-1,3-diones et leur utilisation comme agents anti-inflammatoires
GB9711220D0 (en) * 1997-05-30 1997-07-23 Isis Innovation Antiarrhythmic agents
EP1514869A1 (fr) * 2002-06-12 2005-03-16 Sumitomo Pharmaceuticals Company, Limited Indole, indazole, et derive benzazole
PL383550A1 (pl) * 2007-10-15 2009-04-27 Uniwersytet Łódzki Nowe pochodne benzeno- i pirydopirydazynonów
US9745308B2 (en) * 2014-09-12 2017-08-29 Chiesi Farmaceutici S.P.A. Pyridazinone derivatives as phoshoinositide 3-kinases inhibitors

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR4290M (fr) * 1964-06-05 1966-07-18
US3478149A (en) * 1962-01-24 1969-11-11 Mead Johnson & Co Therapeutic compositions and methods employing sulfonamidophenethanolamines
GB993584A (fr) * 1962-01-24
LU47776A1 (fr) * 1964-07-30 1966-07-13
US3758692A (en) * 1969-04-14 1973-09-11 Mead Johnson & Co Ylamines sympathomimetic process and compositions employing sulfonamidophenalk
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
GB1263987A (en) * 1969-05-30 1972-02-16 Allen & Hanburys Ltd Phenethylamine derivatives
US3623623A (en) * 1969-09-05 1971-11-30 Reflex Corp Canada Ltd Childproof safety package
BE757005A (fr) * 1969-10-02 1971-04-02 Bristol Myers Co Phenethanolamines substituees et procede pour leur preparation
US4087541A (en) * 1975-03-06 1978-05-02 Boehringer Ingelheim Gmbh 2-(Aralkylaminoalkyl)phthalimidines
DD123741A5 (fr) * 1975-03-06 1977-01-12
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
DE2639291A1 (de) * 1976-09-01 1978-03-02 Thomae Gmbh Dr K Neue aryl-alkylamine
DE2639718C2 (de) * 1976-09-03 1987-03-05 Dr. Karl Thomae Gmbh, 7950 Biberach 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel
CH645628A5 (en) * 1977-01-01 1984-10-15 Thomae Gmbh Dr K Phenylethylamines
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
FR2533563A1 (fr) * 1982-09-23 1984-03-30 Adir Nouveaux derives de la sulfonyluree, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
EP0164865B1 (fr) * 1984-05-04 1988-12-21 The Upjohn Company N-(aminoalcoylphényl)sulfonamides, leur préparation et leur utilisation thérapeutique
JPS61124941A (ja) * 1984-11-21 1986-06-12 Fuji Photo Film Co Ltd 加熱工程を有する画像形成方法
GB8609331D0 (en) * 1986-04-16 1986-05-21 Pfizer Ltd Anti-arrythmia agents
DE3623944A1 (de) * 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
HU198014B (en) 1989-07-28
AU575745B2 (en) 1988-08-04
CA1295616C (fr) 1992-02-11
GB8609331D0 (en) 1986-05-21
KR870010012A (ko) 1987-11-30
HUT44528A (en) 1988-03-28
IL82205A0 (en) 1987-10-30
AU7144287A (en) 1987-12-10
PT84675A (en) 1987-05-01
FI871635A0 (fi) 1987-04-14
PT84675B (pt) 1989-11-30
JPS62255474A (ja) 1987-11-07
NZ219990A (en) 1989-08-29
ZA872703B (en) 1989-07-26
US4863948A (en) 1989-09-05
EP0242173A1 (fr) 1987-10-21
DK195087A (da) 1987-10-17
FI871635A (fi) 1987-10-17
US4990509A (en) 1991-02-05
DK195087D0 (da) 1987-04-15
US5114952A (en) 1992-05-19

Similar Documents

Publication Publication Date Title
NZ220345A (en) Imidazoquinolinylether derivatives and pharmaceutical compositions containing them
NZ220880A (en) Di-tert-butyl-phenol derivatives and pharmaceutical compositions
IL82221A0 (en) Phenyl-piperazines and pharmaceutical compositions containing them
NZ221996A (en) Imidazo-pyridine derivatives and pharmaceutical compositions
NZ222980A (en) 3-aryloxy-3-substituted propanamines and pharmaceutical compositions
NZ223096A (en) Peptidylaminodiols and pharmaceutical compositions
NZ216793A (en) Phenethanolaminotetraline derivatives and pharmaceutical compositions
IL88988A0 (en) Didehydro-vitamin d3 derivatives and pharmaceutical compositions containing them
NZ220171A (en) Dihydro-benzopyran derivatives and pharmaceutical compositions
NZ222756A (en) Tetrahydropyridine derivatives and pharmaceutical compositions
GR871659B (en) Substituted a-aminoacids their preparation and pharmaceutical compositions containing them
IL74865A0 (en) 9a-aza-9a-homoerythromycin derivatives and pharmaceutical compositions containing them
IL82205A0 (en) Substituted alkanesulfonamidophenyl derivatives and pharmaceutical compositions containing them
IL79376A0 (en) Substituted di-t-butylphenols and pharmaceutical compositions containing them
IL76188A (en) 3-aralkylidene-hydroxy-flavanone derivatives and pharmaceutical compositions containing them
NZ220336A (en) Isoquinoline derivatives and pharmaceutical compositions containing such
IL86711A0 (en) 5-pyrimidinecarboxamide derivatives and pharmaceutical compositions containing them
NZ217078A (en) N-piperidyl-benzamide derivatives and pharmaceutical compositions
NZ210818A (en) 8-alpha-acylaminoergoline derivatives and pharmaceutical compositions
NZ225466A (en) 1-aminoalkyl-1h-indole derivatives and pharmaceutical compositions containing certain derivatives thereof
GB2167414B (en) Flavolignan derivatives and pharmaceutical compositions containing them
NZ225613A (en) Benzazepin-2-one derivatives and pharmaceutical compositions
NZ216720A (en) Diazinylpiperidine derivatives and pharmaceutical compositions
NZ223051A (en) Carbamoyloxylabdane derivatives and pharmaceutical compositions
IL90171A0 (en) Dideoxynucleoside derivatives and pharmaceutical compositions containing them