IL81733A - 2-substituted methylphenyloxy(thio)methyl penem derivatives and pharmaceutical compositions containing them - Google Patents
2-substituted methylphenyloxy(thio)methyl penem derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL81733A IL81733A IL81733A IL8173387A IL81733A IL 81733 A IL81733 A IL 81733A IL 81733 A IL81733 A IL 81733A IL 8173387 A IL8173387 A IL 8173387A IL 81733 A IL81733 A IL 81733A
- Authority
- IL
- Israel
- Prior art keywords
- sub
- sup
- group
- substituted
- formula
- Prior art date
Links
- -1 2-substituted methylphenyloxy(thio)methyl penem derivatives Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004468 heterocyclylthio group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Mechanical Pencils And Projecting And Retracting Systems Therefor, And Multi-System Writing Instruments (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Pens And Brushes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868605549A GB8605549D0 (en) | 1986-03-06 | 1986-03-06 | Penem derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL81733A0 IL81733A0 (en) | 1987-10-20 |
| IL81733A true IL81733A (en) | 1992-03-29 |
Family
ID=10594154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL81733A IL81733A (en) | 1986-03-06 | 1987-03-02 | 2-substituted methylphenyloxy(thio)methyl penem derivatives and pharmaceutical compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4886793A (xx) |
| EP (1) | EP0236880B1 (xx) |
| JP (1) | JPH0784473B2 (xx) |
| KR (1) | KR870008893A (xx) |
| AT (1) | ATE108796T1 (xx) |
| AU (1) | AU625735B2 (xx) |
| DE (1) | DE3750233T2 (xx) |
| DK (1) | DK115087A (xx) |
| ES (1) | ES2061444T3 (xx) |
| FI (1) | FI87650C (xx) |
| GB (1) | GB8605549D0 (xx) |
| HU (1) | HU198498B (xx) |
| IE (1) | IE870562L (xx) |
| IL (1) | IL81733A (xx) |
| NZ (1) | NZ219478A (xx) |
| PT (1) | PT84419B (xx) |
| SU (1) | SU1579461A3 (xx) |
| ZA (1) | ZA871640B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8605549D0 (en) * | 1986-03-06 | 1986-04-09 | Erba Farmitalia | Penem derivatives |
| DE3882730D1 (de) * | 1987-02-11 | 1993-09-09 | Ciba Geigy Ag | Bicyclische beta-lactam-carbonsaeuren. |
| EP0597401A3 (en) * | 1992-11-11 | 1995-07-26 | Takeda Chemical Industries Ltd | Preparation of penemes. |
| CN100417654C (zh) * | 2004-01-09 | 2008-09-10 | 中国医学科学院医药生物技术研究所 | 2-苯羧酸酯青霉烯类化合物及其制备方法和应用 |
| CN1305875C (zh) * | 2005-04-25 | 2007-03-21 | 中国医学科学院医药生物技术研究所 | 取代2－苯甲酰哌嗪甲基青霉烯类化合物及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4272437A (en) * | 1978-12-18 | 1981-06-09 | Bristol-Myers Company | Antibacterial agents, and 4-thio azetidinone intermediates |
| US4482565A (en) * | 1980-02-22 | 1984-11-13 | Farmitalia Carlo Erba S.P.A. | β-Lactam-containing antibacterial agents and β-lactamase inhibitors |
| US4558042A (en) * | 1981-05-06 | 1985-12-10 | Farmitalia Carlo Erba S.P.A. | β-Lactam-containing antibacterial agents and β-lactamase inhibitors |
| ES513672A0 (es) * | 1981-07-08 | 1983-04-01 | Hoechst Uk Ltd | "procedimiento para la preparacion de derivados de penem". |
| DE3277696D1 (en) * | 1981-07-15 | 1987-12-23 | Sumitomo Pharma | Carboxylic beta-lactam compounds and the preparation thereof |
| NO831160L (no) * | 1982-04-08 | 1983-10-10 | Erba Farmitalia | Fremstilling av substituerte penem-derivater |
| GB8416652D0 (en) * | 1984-06-29 | 1984-08-01 | Erba Farmitalia | Penem derivatives |
| GB8416651D0 (en) * | 1984-06-29 | 1984-08-01 | Erba Farmitalia | Penem derivatives |
| GB8509180D0 (en) * | 1985-04-10 | 1985-05-15 | Erba Farmitalia | Penem derivatives |
| GB8605549D0 (en) * | 1986-03-06 | 1986-04-09 | Erba Farmitalia | Penem derivatives |
| GB2187448B (en) * | 1986-03-06 | 1990-10-24 | Erba Farmitalia | Penem derivatives |
| DE3882730D1 (de) * | 1987-02-11 | 1993-09-09 | Ciba Geigy Ag | Bicyclische beta-lactam-carbonsaeuren. |
-
1986
- 1986-03-06 GB GB868605549A patent/GB8605549D0/en active Pending
-
1987
- 1987-02-27 AT AT87102825T patent/ATE108796T1/de not_active IP Right Cessation
- 1987-02-27 DE DE3750233T patent/DE3750233T2/de not_active Expired - Fee Related
- 1987-02-27 EP EP87102825A patent/EP0236880B1/en not_active Expired - Lifetime
- 1987-02-27 ES ES87102825T patent/ES2061444T3/es not_active Expired - Lifetime
- 1987-03-02 IL IL81733A patent/IL81733A/xx unknown
- 1987-03-03 FI FI870934A patent/FI87650C/fi not_active IP Right Cessation
- 1987-03-03 NZ NZ219478A patent/NZ219478A/xx unknown
- 1987-03-03 AU AU69631/87A patent/AU625735B2/en not_active Ceased
- 1987-03-05 DK DK115087A patent/DK115087A/da not_active Application Discontinuation
- 1987-03-05 US US07/022,247 patent/US4886793A/en not_active Expired - Fee Related
- 1987-03-05 IE IE870562A patent/IE870562L/xx unknown
- 1987-03-05 SU SU874202195A patent/SU1579461A3/ru active
- 1987-03-06 JP JP62051848A patent/JPH0784473B2/ja not_active Expired - Lifetime
- 1987-03-06 PT PT84419A patent/PT84419B/pt not_active IP Right Cessation
- 1987-03-06 HU HU87963A patent/HU198498B/hu not_active IP Right Cessation
- 1987-03-06 ZA ZA871640A patent/ZA871640B/xx unknown
- 1987-03-06 KR KR870002006A patent/KR870008893A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK115087D0 (da) | 1987-03-05 |
| AU625735B2 (en) | 1992-07-16 |
| EP0236880B1 (en) | 1994-07-20 |
| JPH0784473B2 (ja) | 1995-09-13 |
| FI87650B (fi) | 1992-10-30 |
| IL81733A0 (en) | 1987-10-20 |
| HU198498B (en) | 1989-10-30 |
| AU6963187A (en) | 1987-09-10 |
| FI87650C (fi) | 1993-02-10 |
| NZ219478A (en) | 1989-06-28 |
| DE3750233D1 (de) | 1994-08-25 |
| GB8605549D0 (en) | 1986-04-09 |
| IE870562L (en) | 1987-09-06 |
| PT84419B (pt) | 1989-10-04 |
| US4886793A (en) | 1989-12-12 |
| EP0236880A3 (en) | 1988-04-06 |
| DE3750233T2 (de) | 1994-10-27 |
| FI870934A (fi) | 1987-09-07 |
| DK115087A (da) | 1987-09-07 |
| JPS62270588A (ja) | 1987-11-24 |
| KR870008893A (ko) | 1987-10-22 |
| FI870934A0 (fi) | 1987-03-03 |
| HUT43612A (en) | 1987-11-30 |
| SU1579461A3 (ru) | 1990-07-15 |
| EP0236880A2 (en) | 1987-09-16 |
| ES2061444T3 (es) | 1994-12-16 |
| PT84419A (en) | 1987-04-01 |
| ZA871640B (en) | 1988-05-25 |
| ATE108796T1 (de) | 1994-08-15 |
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