IL81565A - Dihydropyridine-dicarboxylic acid esters,their preparation and pharmaceutical compositions containing them - Google Patents

Dihydropyridine-dicarboxylic acid esters,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL81565A
IL81565A IL81565A IL8156587A IL81565A IL 81565 A IL81565 A IL 81565A IL 81565 A IL81565 A IL 81565A IL 8156587 A IL8156587 A IL 8156587A IL 81565 A IL81565 A IL 81565A
Authority
IL
Israel
Prior art keywords
sub
alkyl
group
straight
dihydropyridine
Prior art date
Application number
IL81565A
Other languages
English (en)
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of IL81565A publication Critical patent/IL81565A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL81565A 1986-02-20 1987-02-13 Dihydropyridine-dicarboxylic acid esters,their preparation and pharmaceutical compositions containing them IL81565A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8619485A IT1204461B (it) 1986-02-20 1986-02-20 Derivati eterociclici

Publications (1)

Publication Number Publication Date
IL81565A true IL81565A (en) 1991-09-16

Family

ID=11158424

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81565A IL81565A (en) 1986-02-20 1987-02-13 Dihydropyridine-dicarboxylic acid esters,their preparation and pharmaceutical compositions containing them

Country Status (7)

Country Link
US (1) US5051432A (de)
EP (1) EP0238211B1 (de)
JP (1) JPS62252782A (de)
AT (1) ATE100083T1 (de)
DE (1) DE3788738T2 (de)
IL (1) IL81565A (de)
IT (1) IT1204461B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080089947A1 (en) * 2006-08-18 2008-04-17 Knox Clayton D Calcium Influx Inhibitors in the Treatment of Ischemia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE2847236A1 (de) * 1978-10-31 1980-05-14 Bayer Ag Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS57171968A (en) * 1981-04-17 1982-10-22 Kyowa Hakko Kogyo Co Ltd 1,4-dihydropyridine derivative
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
IT1204461B (it) 1989-03-01
US5051432A (en) 1991-09-24
DE3788738D1 (de) 1994-02-24
EP0238211A3 (en) 1988-09-07
IT8619485A0 (it) 1986-02-20
EP0238211B1 (de) 1994-01-12
DE3788738T2 (de) 1994-04-28
JPS62252782A (ja) 1987-11-04
ATE100083T1 (de) 1994-01-15
EP0238211A2 (de) 1987-09-23

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees