IL81209A - Substituted 6h-indolo(2,3-b)-quinoxalines,their preparation and pharmaceutical compositions comprising them - Google Patents
Substituted 6h-indolo(2,3-b)-quinoxalines,their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- IL81209A IL81209A IL81209A IL8120987A IL81209A IL 81209 A IL81209 A IL 81209A IL 81209 A IL81209 A IL 81209A IL 8120987 A IL8120987 A IL 8120987A IL 81209 A IL81209 A IL 81209A
- Authority
- IL
- Israel
- Prior art keywords
- indolo
- quinoxalines
- substituted
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8600260A SE8600260D0 (sv) | 1986-01-21 | 1986-01-21 | Substituerade indolokinoxaliner |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL81209A0 IL81209A0 (en) | 1987-08-31 |
| IL81209A true IL81209A (en) | 1991-04-15 |
Family
ID=20363170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL81209A IL81209A (en) | 1986-01-21 | 1987-01-08 | Substituted 6h-indolo(2,3-b)-quinoxalines,their preparation and pharmaceutical compositions comprising them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4990510A (fi) |
| EP (1) | EP0238459B1 (fi) |
| JP (1) | JPH07107066B2 (fi) |
| KR (1) | KR880700801A (fi) |
| AP (1) | AP27A (fi) |
| AT (1) | ATE74920T1 (fi) |
| AU (1) | AU606047B2 (fi) |
| CA (1) | CA1303613C (fi) |
| DE (1) | DE3778190D1 (fi) |
| DK (1) | DK492587A (fi) |
| ES (1) | ES2037105T3 (fi) |
| FI (1) | FI883373A0 (fi) |
| HU (1) | HU201937B (fi) |
| IL (1) | IL81209A (fi) |
| NO (1) | NO873945D0 (fi) |
| OA (1) | OA08744A (fi) |
| RU (1) | RU1776259C (fi) |
| SE (1) | SE8600260D0 (fi) |
| WO (1) | WO1987004436A1 (fi) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8600261D0 (sv) * | 1986-01-21 | 1986-01-21 | Lundblad Leif | Indolokinoxaliner med substituenter i 6-position som innehaller cykliska grupper |
| US5597921A (en) * | 1993-04-22 | 1997-01-28 | Taisho Pharmaceutical Co., Ltd. | Indolo[2,3-b]quinoxaline derivatives |
| US5700823A (en) * | 1994-01-07 | 1997-12-23 | Sugen, Inc. | Treatment of platelet derived growth factor related disorders such as cancers |
| SE504289C2 (sv) * | 1994-06-23 | 1996-12-23 | Leif J I Lundblad | Användning av vissa indolo-2,3b-kinoxaliner för framställning av ett läkemedel för inhibering av enzymet HIV-integras |
| SE504862C2 (sv) * | 1994-12-27 | 1997-05-20 | Leif J I Lundblad | Användning av vissa indolo-§2,3b¤-kinoxaliner för framställning av ett läkemedel för skydd av DNA i initieringsfasen och/eller promotionsfasen av karcinogenes och för förhindrande av oxidativ stress i patienter med sjukdomar relaterade till fria radikaler |
| US5721277A (en) * | 1995-04-21 | 1998-02-24 | Sugen, Inc. | Compounds and methods for inhibiting hyper-proliferative cell growth |
| US6331555B1 (en) | 1995-06-01 | 2001-12-18 | University Of California | Treatment of platelet derived growth factor related disorders such as cancers |
| US6465466B1 (en) | 1995-12-22 | 2002-10-15 | Leif J. I. Lundblad | Uses of indolo-2 [2,3b] -quinoxalines |
| US6316479B1 (en) | 1997-05-19 | 2001-11-13 | Sugen, Inc. | Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders |
| SE9704723D0 (sv) * | 1997-12-17 | 1997-12-17 | Leif J I Lundblad | Ligands |
| US6333327B2 (en) * | 2000-02-18 | 2001-12-25 | Leif J. I. Lundblad | Method for the treatment of Multiple Sclerosis |
| SE516067C2 (sv) * | 2000-02-18 | 2001-11-12 | Lundblad Leif J I | Användning av en förening för framställning av ett läkemedel |
| GB0022922D0 (en) * | 2000-09-19 | 2000-11-01 | Chapman Robert E | Compounds for use in medicine |
| SE529777C2 (sv) * | 2006-01-23 | 2007-11-20 | Vironova Ab | Nya föreningar och användning därav |
| EP2128160B1 (en) | 2008-04-30 | 2010-07-14 | Universität Duisburg-Essen | Indolo[2,3-b]-, Indeno[1,2-b]- and Indeno[2,1-b]pyrido[2,3-f] quinoxaline-3-carboxylic acids and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents |
| EP2489354A1 (en) * | 2011-02-18 | 2012-08-22 | Vironova AB | Pharmaceutical formulation of B220 for topical treatment of herpes |
| CN105061432B (zh) * | 2015-07-16 | 2017-09-29 | 河北大学 | 6H‑吲哚[2,3‑b]喹喔啉衍生物、药物组合物及其制备和应用 |
| US20230312578A1 (en) | 2020-06-29 | 2023-10-05 | Vironova Medical Ab | 6h-indolo[2,3-b]quinoxaline derivatives useful in therapy |
| WO2022002898A1 (en) | 2020-06-29 | 2022-01-06 | Vironova Medical Ab | 6h-indolo(2,3-b)quinoxaline derivatives useful in therapy in particular in a virus infection |
-
1986
- 1986-01-21 SE SE8600260A patent/SE8600260D0/xx unknown
-
1987
- 1987-01-08 IL IL81209A patent/IL81209A/xx not_active IP Right Cessation
- 1987-01-09 AP APAP/P/1987/000055A patent/AP27A/en active
- 1987-01-19 WO PCT/SE1987/000019 patent/WO1987004436A1/en active Application Filing
- 1987-01-19 JP JP62500757A patent/JPH07107066B2/ja not_active Expired - Fee Related
- 1987-01-19 ES ES198787850012T patent/ES2037105T3/es not_active Expired - Lifetime
- 1987-01-19 HU HU847A patent/HU201937B/hu not_active IP Right Cessation
- 1987-01-19 AT AT87850012T patent/ATE74920T1/de not_active IP Right Cessation
- 1987-01-19 US US07/102,147 patent/US4990510A/en not_active Expired - Lifetime
- 1987-01-19 AU AU68995/87A patent/AU606047B2/en not_active Ceased
- 1987-01-19 EP EP87850012A patent/EP0238459B1/en not_active Expired - Lifetime
- 1987-01-19 DE DE8787850012T patent/DE3778190D1/de not_active Expired - Lifetime
- 1987-01-20 CA CA000527660A patent/CA1303613C/en not_active Expired - Lifetime
- 1987-09-18 DK DK492587A patent/DK492587A/da not_active Application Discontinuation
- 1987-09-21 NO NO873945A patent/NO873945D0/no unknown
- 1987-09-21 KR KR870700852A patent/KR880700801A/ko not_active Application Discontinuation
-
1988
- 1988-07-15 FI FI883373A patent/FI883373A0/fi not_active Application Discontinuation
- 1988-07-19 RU SU884356314A patent/RU1776259C/ru active
- 1988-07-21 OA OA59390A patent/OA08744A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI883373A (fi) | 1988-07-15 |
| SE8600260D0 (sv) | 1986-01-21 |
| AU6899587A (en) | 1987-08-14 |
| DK492587D0 (da) | 1987-09-18 |
| EP0238459A1 (en) | 1987-09-23 |
| CA1303613C (en) | 1992-06-16 |
| JPS63502588A (ja) | 1988-09-29 |
| AP27A (en) | 1988-12-02 |
| FI883373A0 (fi) | 1988-07-15 |
| ATE74920T1 (de) | 1992-05-15 |
| HUT47937A (en) | 1989-04-28 |
| DK492587A (da) | 1987-09-18 |
| AU606047B2 (en) | 1991-01-31 |
| AP8700055A0 (en) | 1986-11-01 |
| JPH07107066B2 (ja) | 1995-11-15 |
| US4990510A (en) | 1991-02-05 |
| HU201937B (en) | 1991-01-28 |
| DE3778190D1 (de) | 1992-05-21 |
| ES2037105T3 (es) | 1993-06-16 |
| NO873945L (no) | 1987-09-21 |
| OA08744A (en) | 1989-03-31 |
| KR880700801A (ko) | 1988-04-12 |
| WO1987004436A1 (en) | 1987-07-30 |
| RU1776259C (ru) | 1992-11-15 |
| EP0238459B1 (en) | 1992-04-15 |
| IL81209A0 (en) | 1987-08-31 |
| NO873945D0 (no) | 1987-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |