IL80448A - Purified tnf composition - Google Patents

Purified tnf composition

Info

Publication number
IL80448A
IL80448A IL80448A IL8044886A IL80448A IL 80448 A IL80448 A IL 80448A IL 80448 A IL80448 A IL 80448A IL 8044886 A IL8044886 A IL 8044886A IL 80448 A IL80448 A IL 80448A
Authority
IL
Israel
Prior art keywords
purified tnf
tnf composition
composition
purified
tnf
Prior art date
Application number
IL80448A
Other languages
English (en)
Other versions
IL80448A0 (en
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/792,815 external-priority patent/US4677197A/en
Priority claimed from US06/866,213 external-priority patent/US4894439A/en
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of IL80448A0 publication Critical patent/IL80448A0/xx
Publication of IL80448A publication Critical patent/IL80448A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL80448A 1985-10-30 1986-10-29 Purified tnf composition IL80448A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/792,815 US4677197A (en) 1985-10-30 1985-10-30 Purification method for tumor necrosis factor
US06/866,213 US4894439A (en) 1986-05-22 1986-05-22 N-terminal derivatives of tumor necrosis factor purified by microporous PTFE membranes

Publications (2)

Publication Number Publication Date
IL80448A0 IL80448A0 (en) 1987-01-30
IL80448A true IL80448A (en) 1991-01-31

Family

ID=27121338

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80448A IL80448A (en) 1985-10-30 1986-10-29 Purified tnf composition

Country Status (9)

Country Link
EP (1) EP0220966A3 (no)
AU (1) AU6449586A (no)
CA (1) CA1286843C (no)
DK (1) DK520086A (no)
FI (1) FI864412A (no)
IL (1) IL80448A (no)
MX (1) MX166995B (no)
NO (1) NO864321L (no)
NZ (1) NZ218103A (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689401A (en) * 1986-03-06 1987-08-25 Cetus Corporation Method of recovering microbially produced recombinant ricin toxin a chain
JPS62298536A (ja) * 1986-06-17 1987-12-25 Green Cross Corp:The 生理活性物質の自動精製方法および自動精製装置
US4771128A (en) * 1986-10-10 1988-09-13 Cetus Corporation Method of purifying toxin conjugates using hydrophobic interaction chromatography
US4808314A (en) * 1987-09-18 1989-02-28 Scripps Clinic And Research Foundation Method for reducing bacterial endotoxin contamination in solutions of macromolecules
PT88783B (pt) * 1987-10-23 1993-01-29 Smithkline Beckman Corp Processo de purificacao de proteina t4 soluvel e de producao da mesma
CA1341379C (en) * 1988-04-28 2002-07-23 Welfide Corporation Purified antithrombin-iii and methods of producing the same
LT3062B (en) 1992-09-03 1994-10-25 Fermentas Biotech Inst Method for preparing recombinant human tumour necrolysis factor-alpha
US7642340B2 (en) * 2003-03-31 2010-01-05 Xencor, Inc. PEGylated TNF-α variant proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582183D1 (de) * 1984-03-06 1991-04-25 Dainippon Pharmaceutical Co Dns den menschlichen tumornekrosisfaktor kodierend und das menschliche tumornekronisfaktor-polypeptid.
WO1986002381A1 (en) * 1984-10-15 1986-04-24 Cetus Corporation Human tumor necrosis factor
EP0205038A1 (en) * 1985-05-29 1986-12-17 Suntory Limited Polypeptide, process for preparing it, microorganism and pharmaceutical use

Also Published As

Publication number Publication date
NO864321D0 (no) 1986-10-29
FI864412A (fi) 1987-05-01
EP0220966A2 (en) 1987-05-06
EP0220966A3 (en) 1989-08-23
NZ218103A (en) 1988-10-28
MX166995B (es) 1993-02-19
CA1286843C (en) 1991-07-23
NO864321L (no) 1987-05-04
DK520086A (da) 1987-05-01
DK520086D0 (da) 1986-10-30
IL80448A0 (en) 1987-01-30
AU6449586A (en) 1987-05-07
FI864412A0 (fi) 1986-10-29

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Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
RH Patent void