DK520086A - Fremgangsmaade til delvis oprensning af et biologisk aktivt protein, herunder tumornekrosefaktor, samt det herved produkt og pharmaceutisk praeparat indeholdende samme - Google Patents

Fremgangsmaade til delvis oprensning af et biologisk aktivt protein, herunder tumornekrosefaktor, samt det herved produkt og pharmaceutisk praeparat indeholdende samme

Info

Publication number
DK520086A
DK520086A DK520086A DK520086A DK520086A DK 520086 A DK520086 A DK 520086A DK 520086 A DK520086 A DK 520086A DK 520086 A DK520086 A DK 520086A DK 520086 A DK520086 A DK 520086A
Authority
DK
Denmark
Prior art keywords
procedure
product
biologically active
same
pharmaceutical preparation
Prior art date
Application number
DK520086A
Other languages
Danish (da)
English (en)
Other versions
DK520086D0 (da
Inventor
Leo Shun-Lee Lin
Wolfgang Helmut Hanisch
Ralph Yamamoto
James William Thomson
Glenn Dorin
Sidney Norman Wolfe
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/792,815 external-priority patent/US4677197A/en
Priority claimed from US06/866,213 external-priority patent/US4894439A/en
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of DK520086D0 publication Critical patent/DK520086D0/da
Publication of DK520086A publication Critical patent/DK520086A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK520086A 1985-10-30 1986-10-30 Fremgangsmaade til delvis oprensning af et biologisk aktivt protein, herunder tumornekrosefaktor, samt det herved produkt og pharmaceutisk praeparat indeholdende samme DK520086A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/792,815 US4677197A (en) 1985-10-30 1985-10-30 Purification method for tumor necrosis factor
US06/866,213 US4894439A (en) 1986-05-22 1986-05-22 N-terminal derivatives of tumor necrosis factor purified by microporous PTFE membranes

Publications (2)

Publication Number Publication Date
DK520086D0 DK520086D0 (da) 1986-10-30
DK520086A true DK520086A (da) 1987-05-01

Family

ID=27121338

Family Applications (1)

Application Number Title Priority Date Filing Date
DK520086A DK520086A (da) 1985-10-30 1986-10-30 Fremgangsmaade til delvis oprensning af et biologisk aktivt protein, herunder tumornekrosefaktor, samt det herved produkt og pharmaceutisk praeparat indeholdende samme

Country Status (9)

Country Link
EP (1) EP0220966A3 (no)
AU (1) AU6449586A (no)
CA (1) CA1286843C (no)
DK (1) DK520086A (no)
FI (1) FI864412A (no)
IL (1) IL80448A (no)
MX (1) MX166995B (no)
NO (1) NO864321L (no)
NZ (1) NZ218103A (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689401A (en) * 1986-03-06 1987-08-25 Cetus Corporation Method of recovering microbially produced recombinant ricin toxin a chain
JPS62298536A (ja) * 1986-06-17 1987-12-25 Green Cross Corp:The 生理活性物質の自動精製方法および自動精製装置
US4771128A (en) * 1986-10-10 1988-09-13 Cetus Corporation Method of purifying toxin conjugates using hydrophobic interaction chromatography
US4808314A (en) * 1987-09-18 1989-02-28 Scripps Clinic And Research Foundation Method for reducing bacterial endotoxin contamination in solutions of macromolecules
PT88783B (pt) * 1987-10-23 1993-01-29 Smithkline Beckman Corp Processo de purificacao de proteina t4 soluvel e de producao da mesma
CA1341379C (en) * 1988-04-28 2002-07-23 Welfide Corporation Purified antithrombin-iii and methods of producing the same
LT3062B (en) 1992-09-03 1994-10-25 Fermentas Biotech Inst Method for preparing recombinant human tumour necrolysis factor-alpha
US7642340B2 (en) * 2003-03-31 2010-01-05 Xencor, Inc. PEGylated TNF-α variant proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582183D1 (de) * 1984-03-06 1991-04-25 Dainippon Pharmaceutical Co Dns den menschlichen tumornekrosisfaktor kodierend und das menschliche tumornekronisfaktor-polypeptid.
WO1986002381A1 (en) * 1984-10-15 1986-04-24 Cetus Corporation Human tumor necrosis factor
EP0205038A1 (en) * 1985-05-29 1986-12-17 Suntory Limited Polypeptide, process for preparing it, microorganism and pharmaceutical use

Also Published As

Publication number Publication date
NO864321D0 (no) 1986-10-29
FI864412A (fi) 1987-05-01
EP0220966A2 (en) 1987-05-06
EP0220966A3 (en) 1989-08-23
IL80448A (en) 1991-01-31
NZ218103A (en) 1988-10-28
MX166995B (es) 1993-02-19
CA1286843C (en) 1991-07-23
NO864321L (no) 1987-05-04
DK520086D0 (da) 1986-10-30
IL80448A0 (en) 1987-01-30
AU6449586A (en) 1987-05-07
FI864412A0 (fi) 1986-10-29

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