IL80339A - 2-(2-(2-pyridyl)- phenylsulphinyl) -benzimidazoles, their preparation and pharmaceutical compositions containing them - Google Patents

2-(2-(2-pyridyl)- phenylsulphinyl) -benzimidazoles, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL80339A
IL80339A IL80339A IL8033986A IL80339A IL 80339 A IL80339 A IL 80339A IL 80339 A IL80339 A IL 80339A IL 8033986 A IL8033986 A IL 8033986A IL 80339 A IL80339 A IL 80339A
Authority
IL
Israel
Prior art keywords
phenylsulphinyl
benzimidazoles
pyridyl
preparation
pharmaceutical compositions
Prior art date
Application number
IL80339A
Other languages
English (en)
Other versions
IL80339A0 (en
Original Assignee
Fisons Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858525452A external-priority patent/GB8525452D0/en
Priority claimed from GB858525454A external-priority patent/GB8525454D0/en
Priority claimed from GB868621768A external-priority patent/GB8621768D0/en
Application filed by Fisons Plc filed Critical Fisons Plc
Publication of IL80339A0 publication Critical patent/IL80339A0/xx
Publication of IL80339A publication Critical patent/IL80339A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IL80339A 1985-10-16 1986-10-16 2-(2-(2-pyridyl)- phenylsulphinyl) -benzimidazoles, their preparation and pharmaceutical compositions containing them IL80339A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB858525452A GB8525452D0 (en) 1985-10-16 1985-10-16 Biologically active nitrogen heterocycles
GB858525454A GB8525454D0 (en) 1985-10-16 1985-10-16 Biologically active nitrogen heterocycles
GB868621768A GB8621768D0 (en) 1986-09-10 1986-09-10 N heterocyclic compounds

Publications (2)

Publication Number Publication Date
IL80339A0 IL80339A0 (en) 1987-01-30
IL80339A true IL80339A (en) 1993-06-10

Family

ID=27262821

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80339A IL80339A (en) 1985-10-16 1986-10-16 2-(2-(2-pyridyl)- phenylsulphinyl) -benzimidazoles, their preparation and pharmaceutical compositions containing them

Country Status (9)

Country Link
US (1) US4851419A (da)
EP (1) EP0220053A3 (da)
KR (1) KR870003995A (da)
AU (1) AU599607B2 (da)
DK (1) DK493386A (da)
FI (1) FI864138A (da)
IL (1) IL80339A (da)
NO (1) NO167569C (da)
NZ (1) NZ217965A (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
US4824856A (en) * 1985-08-14 1989-04-25 Nippon Chemiphar Co., Ltd. Method of protecting gastrointestinal tract
DE3773240D1 (de) * 1986-03-28 1991-10-31 Otsuka Pharma Co Ltd Hydrochinolinverbindungen, diese enthaltende zusammensetzungen und verfahren zu ihrer herstellung.
AU619444B2 (en) * 1986-06-02 1992-01-30 Nippon Chemiphar Co. Ltd. 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives
EP0262845A1 (en) * 1986-09-27 1988-04-06 FISONS plc Heterocyclic substituted azole derivatives
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
AT389107B (de) * 1987-12-03 1989-10-25 Fisons Plc Neue benzimidazole, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
GB9115534D0 (en) * 1991-07-18 1991-09-04 Fisons Plc Compounds
ES2036948B1 (es) * 1991-11-21 1994-09-01 Genesis Para La Investigacion Procedimiento de obtencion de compuestos derivados de piridina.
KR0168978B1 (ko) * 1995-07-12 1999-01-15 김종인 헤테로고리 접합 티아졸 유도체
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
US6200995B1 (en) * 1998-01-29 2001-03-13 Tularik Inc. PPAR-γ modulators
US6583157B2 (en) 1998-01-29 2003-06-24 Tularik Inc. Quinolinyl and benzothiazolyl modulators
US7041691B1 (en) * 1999-06-30 2006-05-09 Amgen Inc. Compounds for the modulation of PPARγ activity
US6653332B2 (en) 2000-05-03 2003-11-25 Tularik Inc. Combination therapeutic compositions and method of use
US20030171399A1 (en) * 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
US7718722B2 (en) * 2000-11-21 2010-05-18 Flexsys America L.P. Alkylthio- and aryl(heteroyl)thio-substituted p-phenylenediamines, their manufacture and their use in rubber
SE0104331D0 (sv) * 2001-12-19 2001-12-19 Astrazeneca Ab Novel compounds
US7223761B2 (en) 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
US20050250820A1 (en) * 2004-03-08 2005-11-10 Amgen Inc. Therapeutic modulation of PPARgamma activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CA1259070A (en) * 1983-07-01 1989-09-05 Upjohn Company (The) Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl|-benzimidazoles

Also Published As

Publication number Publication date
NO167569B (no) 1991-08-12
DK493386D0 (da) 1986-10-15
EP0220053A2 (en) 1987-04-29
KR870003995A (ko) 1987-05-06
IL80339A0 (en) 1987-01-30
NO167569C (no) 1991-11-20
NO864110D0 (no) 1986-10-15
AU6416986A (en) 1987-04-30
EP0220053A3 (en) 1988-02-10
FI864138A (fi) 1987-04-17
NZ217965A (en) 1990-09-26
US4851419A (en) 1989-07-25
AU599607B2 (en) 1990-07-26
FI864138A0 (fi) 1986-10-14
DK493386A (da) 1987-04-17
NO864110L (no) 1987-04-21

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Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void