IL79681A - Transition metal complexes of growth hormones and their prolonged release compositions - Google Patents
Transition metal complexes of growth hormones and their prolonged release compositionsInfo
- Publication number
- IL79681A IL79681A IL79681A IL7968186A IL79681A IL 79681 A IL79681 A IL 79681A IL 79681 A IL79681 A IL 79681A IL 7968186 A IL7968186 A IL 7968186A IL 79681 A IL79681 A IL 79681A
- Authority
- IL
- Israel
- Prior art keywords
- transition metal
- metal complexes
- prolonged release
- release compositions
- growth hormones
- Prior art date
Links
- 239000000122 growth hormone Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000002035 prolonged effect Effects 0.000 title 1
- 229910052723 transition metal Inorganic materials 0.000 title 1
- 150000003624 transition metals Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76440085A | 1985-08-12 | 1985-08-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL79681A0 IL79681A0 (en) | 1986-11-30 |
IL79681A true IL79681A (en) | 1991-06-10 |
Family
ID=25070628
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL79681A IL79681A (en) | 1985-08-12 | 1986-08-11 | Transition metal complexes of growth hormones and their prolonged release compositions |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0216485A1 (es) |
JP (1) | JPS6248635A (es) |
KR (1) | KR870001825A (es) |
CN (1) | CN86105023A (es) |
AU (1) | AU596112B2 (es) |
BR (1) | BR8603848A (es) |
DK (1) | DK384286A (es) |
ES (1) | ES2000864A6 (es) |
IL (1) | IL79681A (es) |
NZ (1) | NZ217175A (es) |
PT (1) | PT83187B (es) |
ZA (1) | ZA866052B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0343696B1 (en) * | 1984-10-04 | 1996-01-03 | Monsanto Company | Zinc-associated somatotropins |
CA1285874C (en) * | 1985-08-23 | 1991-07-09 | Thomas Harry Ferguson | Injectable sustained release formulation |
CA1257199A (en) * | 1986-05-20 | 1989-07-11 | Paul Y. Wang | Preparation containing bioactive macromolecular substance for multi-months release in vivo |
PL270368A1 (en) * | 1987-01-30 | 1988-10-13 | Int Minerals & Chem Corp | Method for recovery of somatotropins from diluted water solutions |
US4863736A (en) * | 1987-03-16 | 1989-09-05 | Monsanto Company | Somatotropin prolonged release |
US5122512A (en) * | 1988-09-12 | 1992-06-16 | Pitman-Moore, Inc. | Swine growth promoting composition |
AU653325B2 (en) * | 1990-02-12 | 1994-09-29 | Lucky Limited | A composition durably releasing bioactive polypeptides |
DK168790D0 (es) * | 1990-07-13 | 1990-07-13 | Novo Nordisk As | |
US5780599A (en) * | 1990-07-13 | 1998-07-14 | Novo Nordisk A/S | Growth hormone crystals and a process for production of growth hormone crystals |
US6894023B1 (en) | 1990-07-13 | 2005-05-17 | Novo Nordisk A/S | Growth hormone crystals and a process for production of these GH-crystals |
WO1992017200A2 (en) * | 1991-03-28 | 1992-10-15 | Genentech, Inc. | Stable growth hormone metal ion formulations |
YU87892A (sh) * | 1991-10-01 | 1995-12-04 | Eli Lilly And Company Lilly Corporate Center | Injektibilne formulacije produženog otpuštanja i postupci za njihovo dobijanje i primenu |
US6022858A (en) * | 1991-12-20 | 2000-02-08 | Novo Nordisk A/S | Pharmaceutical formulation of human-growth hormone pretreated with zinc salt |
US6087324A (en) * | 1993-06-24 | 2000-07-11 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
SE9303068D0 (sv) * | 1993-09-21 | 1993-09-21 | Kabi Pharmacia Ab | New use |
EP0779806B2 (en) * | 1994-09-09 | 2008-04-16 | Takeda Pharmaceutical Company Limited | Sustained release preparation containing metal salt of a peptide |
ATE268591T1 (de) | 1995-06-27 | 2004-06-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von zubereitungen mit verzögerter freisetzung |
US6191107B1 (en) * | 1997-09-26 | 2001-02-20 | Takeda Chemical Industries, Ltd. | Complex of human growth hormone and zinc |
US6451347B1 (en) * | 1999-03-01 | 2002-09-17 | Alkermes Controlled Therapeutics, Inc. | Method for purifying human growth hormone |
KR20090007504A (ko) | 2000-02-24 | 2009-01-16 | 몬산토 테크놀로지 엘엘씨 | 소마토트로핀의 지속적인 방출을 위한 비수성 주사제제들 |
DK1274459T3 (da) | 2000-04-19 | 2006-02-06 | Genentech Inc | Præparater med vedholdende frigivelse indeholdende væksthormon |
WO2002000261A2 (en) | 2000-06-26 | 2002-01-03 | Monsanto Technology Llc | Surfactant-containing formulations for extended release of somatotropin |
US6664234B1 (en) | 2000-06-30 | 2003-12-16 | Monsanto Technology Llc | Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin |
JP2004515467A (ja) | 2000-08-07 | 2004-05-27 | ネクター セラピューティックス | 吸入可能な、噴霧乾燥した、最少の凝集物を有する4−ヘリックスバンドルタンパク質粉末 |
DK1372729T3 (da) | 2001-02-23 | 2009-06-22 | Genentech Inc | Nedbrydelige polymere til injektion |
WO2003000282A1 (en) * | 2001-06-21 | 2003-01-03 | Genentech, Inc. | Sustained release formulation |
SG176314A1 (en) | 2002-12-31 | 2011-12-29 | Altus Pharmaceuticals Inc | Human growth hormone crystals and methods for preparing them |
CA2512001A1 (en) * | 2002-12-31 | 2004-07-22 | Altus Pharmaceuticals Inc. | Complexes of protein crystals and ionic polymers |
NZ600363A (en) | 2009-12-21 | 2014-07-25 | Ambrx Inc | Modified porcine somatotropin polypeptides and their uses |
CN102753573A (zh) | 2009-12-21 | 2012-10-24 | Ambrx公司 | 经过修饰的牛促生长素多肽和其用途 |
US20160303242A1 (en) | 2013-12-09 | 2016-10-20 | Durect Corporation | Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB885798A (en) * | 1958-12-06 | 1961-12-28 | Organon Labor Ltd | Preparations of the growth hormone |
DK100792C (da) * | 1961-05-23 | 1965-01-18 | Dumex Ltd As | Fremgangsmåde til fremstilling af et præparat med protraheret vitamin B12-virkning. |
DE2158123A1 (de) * | 1970-12-02 | 1972-06-08 | Ciba-Geigy Ag, Basel (Schweiz) | Neue pharmazeutische Präparate |
US4333919A (en) * | 1979-09-12 | 1982-06-08 | Eli Lilly And Company | Growth promotant controlled release formulations and method of treatment |
-
1986
- 1986-08-11 IL IL79681A patent/IL79681A/xx unknown
- 1986-08-12 PT PT83187A patent/PT83187B/pt not_active IP Right Cessation
- 1986-08-12 BR BR8603848A patent/BR8603848A/pt unknown
- 1986-08-12 AU AU61092/86A patent/AU596112B2/en not_active Withdrawn - After Issue
- 1986-08-12 KR KR1019860006617A patent/KR870001825A/ko not_active Application Discontinuation
- 1986-08-12 ES ES8601040A patent/ES2000864A6/es not_active Expired
- 1986-08-12 ZA ZA866052A patent/ZA866052B/xx unknown
- 1986-08-12 CN CN198686105023A patent/CN86105023A/zh active Pending
- 1986-08-12 EP EP86306237A patent/EP0216485A1/en not_active Ceased
- 1986-08-12 NZ NZ217175A patent/NZ217175A/xx unknown
- 1986-08-12 DK DK384286A patent/DK384286A/da not_active Application Discontinuation
- 1986-08-12 JP JP61187933A patent/JPS6248635A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL79681A0 (en) | 1986-11-30 |
CN86105023A (zh) | 1988-02-24 |
AU596112B2 (en) | 1990-04-26 |
ZA866052B (en) | 1987-03-25 |
ES2000864A6 (es) | 1988-03-16 |
PT83187B (pt) | 1988-07-01 |
BR8603848A (pt) | 1987-03-24 |
DK384286A (da) | 1987-02-13 |
AU6109286A (en) | 1987-02-19 |
DK384286D0 (da) | 1986-08-12 |
KR870001825A (ko) | 1987-03-28 |
NZ217175A (en) | 1989-11-28 |
PT83187A (en) | 1986-09-01 |
EP0216485A1 (en) | 1987-04-01 |
JPS6248635A (ja) | 1987-03-03 |
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