IL78181A0 - Basic monocarboxyamide derivatives of actagardine having antibiotic activity - Google Patents
Basic monocarboxyamide derivatives of actagardine having antibiotic activityInfo
- Publication number
- IL78181A0 IL78181A0 IL78181A IL7818186A IL78181A0 IL 78181 A0 IL78181 A0 IL 78181A0 IL 78181 A IL78181 A IL 78181A IL 7818186 A IL7818186 A IL 7818186A IL 78181 A0 IL78181 A0 IL 78181A0
- Authority
- IL
- Israel
- Prior art keywords
- actagardine
- derivatives
- basic
- monocarboxyamide
- functions
- Prior art date
Links
- 108010070411 gardimycin Proteins 0.000 title abstract 6
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical class NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- LAWKVNVCUPIOMG-HWWYPGLISA-N gardimycin Chemical compound C1=CC=C2C(C[C@H](C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@H](C)C(=O)NCC(=O)N[C@H](CC)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(O)=O)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](CC)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)N)[C@@H](C)CC)C(C)C)=CNC2=C1 LAWKVNVCUPIOMG-HWWYPGLISA-N 0.000 abstract 5
- 239000000126 substance Substances 0.000 abstract 3
- 230000000845 anti-microbial effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000187844 Actinoplanes Species 0.000 abstract 1
- 241000187712 Actinoplanes sp. Species 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/045—Actinoplanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858507528A GB8507528D0 (en) | 1985-03-22 | 1985-03-22 | Basis monocarboxyamide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL78181A0 true IL78181A0 (en) | 1986-07-31 |
Family
ID=10576477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL78181A IL78181A0 (en) | 1985-03-22 | 1986-03-18 | Basic monocarboxyamide derivatives of actagardine having antibiotic activity |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4684644A (da) |
| EP (1) | EP0195359B1 (da) |
| JP (1) | JPS61227529A (da) |
| KR (1) | KR860007201A (da) |
| AT (1) | ATE48608T1 (da) |
| CA (1) | CA1259985A (da) |
| DE (1) | DE3667469D1 (da) |
| DK (1) | DK165120C (da) |
| ES (1) | ES8705893A1 (da) |
| GB (1) | GB8507528D0 (da) |
| HU (1) | HU199510B (da) |
| IL (1) | IL78181A0 (da) |
| ZA (1) | ZA861424B (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8711066D0 (en) * | 1987-05-11 | 1987-06-17 | Lepetit Spa | Teicoplanin derivatives |
| DE19745583A1 (de) * | 1997-10-15 | 1999-04-22 | Hoechst Marion Roussel De Gmbh | Neues Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung derselben |
| GB0600928D0 (en) | 2006-01-17 | 2006-02-22 | Novacta Biosystems Ltd | Improvements relating to lantibiotics |
| GB0714030D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
| GB0714029D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | Lantibiotic-based compounds having antimicrobial activity |
| EP2387580B1 (en) * | 2009-01-14 | 2014-08-13 | Novacta Biosystems Limited | Deoxyactagardine derivatives |
| GB0900599D0 (en) | 2009-01-14 | 2009-02-18 | Novacta Biosystems Ltd | Treatment |
| JP5731407B2 (ja) * | 2009-02-04 | 2015-06-10 | ノヴァクタ バイオシステムズ リミティッド | アクタガルジン誘導体 |
| US20120309676A1 (en) | 2010-02-02 | 2012-12-06 | Sjoerd Nicolaas Wadman | Lantibiotic Salts |
| GB201001688D0 (en) | 2010-02-02 | 2010-03-17 | Novacta Biosystems Ltd | Compounds |
| GB201013513D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Formulations |
| GB201013509D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Compounds |
| GB201013507D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Compounds |
| GB201013508D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Compounds |
| CN102993188A (zh) * | 2012-11-03 | 2013-03-27 | 浙江大学 | 弗霉素b及其制备方法和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1470407A (en) * | 1974-07-27 | 1977-04-14 | Lepetit Spa | Antibiotic substances |
-
1985
- 1985-03-22 GB GB858507528A patent/GB8507528D0/en active Pending
-
1986
- 1986-02-26 ZA ZA861424A patent/ZA861424B/xx unknown
- 1986-03-12 AT AT86103296T patent/ATE48608T1/de not_active IP Right Cessation
- 1986-03-12 EP EP86103296A patent/EP0195359B1/en not_active Expired
- 1986-03-12 DE DE8686103296T patent/DE3667469D1/de not_active Expired - Lifetime
- 1986-03-18 IL IL78181A patent/IL78181A0/xx not_active IP Right Cessation
- 1986-03-18 DK DK123386A patent/DK165120C/da not_active IP Right Cessation
- 1986-03-21 HU HU861200A patent/HU199510B/hu not_active IP Right Cessation
- 1986-03-21 CA CA000504714A patent/CA1259985A/en not_active Expired
- 1986-03-21 KR KR1019860002100A patent/KR860007201A/ko not_active Ceased
- 1986-03-21 ES ES553227A patent/ES8705893A1/es not_active Expired
- 1986-03-21 US US06/842,523 patent/US4684644A/en not_active Expired - Fee Related
- 1986-03-22 JP JP61064671A patent/JPS61227529A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUT40455A (en) | 1986-12-28 |
| ZA861424B (en) | 1986-12-30 |
| JPS61227529A (ja) | 1986-10-09 |
| ES8705893A1 (es) | 1987-05-16 |
| DE3667469D1 (de) | 1990-01-18 |
| DK165120B (da) | 1992-10-12 |
| EP0195359B1 (en) | 1989-12-13 |
| DK123386D0 (da) | 1986-03-18 |
| KR860007201A (ko) | 1986-10-08 |
| CA1259985A (en) | 1989-09-26 |
| EP0195359A2 (en) | 1986-09-24 |
| ES553227A0 (es) | 1987-05-16 |
| DK123386A (da) | 1986-09-23 |
| DK165120C (da) | 1993-03-01 |
| US4684644A (en) | 1987-08-04 |
| HU199510B (en) | 1990-02-28 |
| ATE48608T1 (de) | 1989-12-15 |
| EP0195359A3 (en) | 1987-12-09 |
| GB8507528D0 (en) | 1985-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |