IL75903A - Di-isopropyl ether solvates of beclomethasone 17,21-dipropionate,their preparation and use - Google Patents

Di-isopropyl ether solvates of beclomethasone 17,21-dipropionate,their preparation and use

Info

Publication number
IL75903A
IL75903A IL8575903A IL7590385A IL75903A IL 75903 A IL75903 A IL 75903A IL 8575903 A IL8575903 A IL 8575903A IL 7590385 A IL7590385 A IL 7590385A IL 75903 A IL75903 A IL 75903A
Authority
IL
Israel
Prior art keywords
beclomethasone
dipropionate
preparation
isopropyl ether
ether solvates
Prior art date
Application number
IL8575903A
Other languages
English (en)
Other versions
IL75903A0 (en
Original Assignee
Hovione Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PT7897284A external-priority patent/PT78972A/pt
Priority claimed from PT8079685A external-priority patent/PT80796B/pt
Application filed by Hovione Int Ltd filed Critical Hovione Int Ltd
Publication of IL75903A0 publication Critical patent/IL75903A0/xx
Publication of IL75903A publication Critical patent/IL75903A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Saccharide Compounds (AREA)
IL8575903A 1984-07-25 1985-07-24 Di-isopropyl ether solvates of beclomethasone 17,21-dipropionate,their preparation and use IL75903A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT7897284A PT78972A (en) 1984-07-25 1984-07-25 Preparation process of a 17,21-dipropionate beclomethasona di-isopropylic ether solution and its utilization
PT8079685A PT80796B (pt) 1985-07-11 1985-07-11 Processo para a preparacao de solvatos etoericos de beclometasona 17,21-dipropionato e utilizacao dos mesmos

Publications (2)

Publication Number Publication Date
IL75903A0 IL75903A0 (en) 1985-12-31
IL75903A true IL75903A (en) 1989-10-31

Family

ID=26653439

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8575903A IL75903A (en) 1984-07-25 1985-07-24 Di-isopropyl ether solvates of beclomethasone 17,21-dipropionate,their preparation and use

Country Status (12)

Country Link
US (1) US4913892A (da)
EP (1) EP0172672B1 (da)
KR (1) KR880001237B1 (da)
AU (1) AU566318B2 (da)
CA (1) CA1274503A (da)
DE (1) DE3561321D1 (da)
DK (1) DK336485A (da)
HK (1) HK58789A (da)
IE (1) IE59086B1 (da)
IL (1) IL75903A (da)
NO (1) NO163899C (da)
NZ (1) NZ212877A (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
PT78973A (en) * 1984-07-25 1984-08-01 Joao Emerico Villax New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid
GB8432063D0 (en) * 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids
MX9203481A (es) * 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
MX9304585A (es) 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
US5962445A (en) 1996-05-09 1999-10-05 Amrad Operations Pty Ltd. Treatment of asthma and airway diseases
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
ES2691033T3 (es) 2007-02-11 2018-11-23 Map Pharmaceuticals Inc. Método de administración terapéutica de DHE para activar el alivio rápido de la migraña a la vez que se reduce al mínimo el perfil de los efectos secundarios

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
ATE3774T1 (de) * 1980-05-02 1983-06-15 Schering Corporation Beclomethason-ester-solvate, verfahren zu ihrer herstellung und herstellung einer formulierung.
GB2107715B (en) * 1981-10-19 1985-11-13 Glaxo Group Ltd Micronised beclomethasone dipropionate monohydrate and powder inhalation compositions containing it

Also Published As

Publication number Publication date
NO852948L (no) 1986-01-27
AU4530585A (en) 1986-01-30
EP0172672A1 (en) 1986-02-26
HK58789A (en) 1989-07-28
DE3561321D1 (en) 1988-02-11
NZ212877A (en) 1988-03-30
US4913892A (en) 1990-04-03
DK336485A (da) 1986-01-26
IE59086B1 (en) 1994-01-12
CA1274503A (en) 1990-09-25
NO163899B (no) 1990-04-30
EP0172672B1 (en) 1988-01-07
KR860001122A (ko) 1986-02-22
DK336485D0 (da) 1985-07-24
IL75903A0 (en) 1985-12-31
AU566318B2 (en) 1987-10-15
NO163899C (no) 1990-08-08
KR880001237B1 (ko) 1988-07-12

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
EXP Patent expired