IL75812A - Process for the preparation of halogenated quinolone-carboxylic acids,and 7-chloro-1-cyclopropyl 1,4-dihydro-4-oxo-3-quinoline-carboxylic acid nitrile intermediates therefor - Google Patents
Process for the preparation of halogenated quinolone-carboxylic acids,and 7-chloro-1-cyclopropyl 1,4-dihydro-4-oxo-3-quinoline-carboxylic acid nitrile intermediates thereforInfo
- Publication number
- IL75812A IL75812A IL75812A IL7581285A IL75812A IL 75812 A IL75812 A IL 75812A IL 75812 A IL75812 A IL 75812A IL 7581285 A IL7581285 A IL 7581285A IL 75812 A IL75812 A IL 75812A
- Authority
- IL
- Israel
- Prior art keywords
- quinoline
- cyclopropyl
- dihydro
- oxo
- chloro
- Prior art date
Links
- -1 7-chloro-1-cyclopropyl 1,4-dihydro-4-oxo-3-quinoline-carboxylic acid nitrile Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL85780A IL85780A (en) | 1984-07-18 | 1985-07-15 | Ethoxy-2-4-dichloro-benzoate,2,4-dichloro-acetonitrile and acrylonitrile derivatives |
IL85780A IL85780A0 (en) | 1984-07-18 | 1988-03-18 | Polyhalobenzoyl-acetonitrile and acrylonitrile derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3426483A DE3426483A1 (de) | 1984-07-18 | 1984-07-18 | Verfahren zur herstellung von halogenierten chinoloncarbonsaeuren |
Publications (2)
Publication Number | Publication Date |
---|---|
IL75812A0 IL75812A0 (en) | 1985-11-29 |
IL75812A true IL75812A (en) | 1988-11-15 |
Family
ID=6240968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL75812A IL75812A (en) | 1984-07-18 | 1985-07-15 | Process for the preparation of halogenated quinolone-carboxylic acids,and 7-chloro-1-cyclopropyl 1,4-dihydro-4-oxo-3-quinoline-carboxylic acid nitrile intermediates therefor |
Country Status (12)
Country | Link |
---|---|
US (4) | US4680401A (xx) |
EP (1) | EP0168737A3 (xx) |
JP (1) | JPS6136265A (xx) |
KR (1) | KR910003616B1 (xx) |
CA (1) | CA1273936A (xx) |
DD (1) | DD236524A5 (xx) |
DE (1) | DE3426483A1 (xx) |
DK (1) | DK325685A (xx) |
ES (1) | ES8604522A1 (xx) |
HU (2) | HU195488B (xx) |
IL (1) | IL75812A (xx) |
ZA (1) | ZA855385B (xx) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3426483A1 (de) * | 1984-07-18 | 1986-01-30 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von halogenierten chinoloncarbonsaeuren |
JPS61118370A (ja) * | 1985-10-30 | 1986-06-05 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸とその製造方法 |
US4772706A (en) * | 1986-01-13 | 1988-09-20 | Warner-Lambert Company | Process for quinoline-3-carboxylic acid antibacterial agents |
DE3615767A1 (de) * | 1986-05-10 | 1987-11-12 | Bayer Ag | Verfahren zur herstellung von 4-hydroxy-chinolin-3-carbonsaeuren |
JPS6416767A (en) * | 1987-07-09 | 1989-01-20 | Dainippon Pharmaceutical Co | 8-halogenoquinoline derivative, its ester and salt |
EP0303291B1 (en) * | 1987-08-14 | 1995-04-26 | Asahi Glass Company Ltd. | Fluorinated benzoyl compounds |
JPH0780815B2 (ja) * | 1988-08-26 | 1995-08-30 | 旭硝子株式会社 | 核フッ素化芳香族カルボン酸エステル類及びその製造方法 |
EP0355774B1 (en) * | 1988-08-26 | 1995-04-26 | Asahi Glass Company Ltd. | Nucleus-fluorinated aromatic carboxylates and processes for their production |
US5656573A (en) * | 1989-09-11 | 1997-08-12 | Rhone-Poulenc Agriculture Ltd. | Herbicidal 4-substituted isoxazoles |
US5650533A (en) * | 1989-09-11 | 1997-07-22 | Rhone-Poulenc Agriculture Ltd. | Intermediates to herbicidal 4-substituted isoxazoles |
GB8920519D0 (en) * | 1989-09-11 | 1989-10-25 | Rhone Poulenc Ltd | New compositions of matter |
US5747424A (en) * | 1989-09-11 | 1998-05-05 | Rhone-Poulenc Agriculture Ltd. | Herbicidal 4-substituted isoxazol |
US5028707A (en) * | 1989-11-20 | 1991-07-02 | Board Of Regents, University Of Texas | 4-hydroxyquinaldic acid derivatives |
US5059709A (en) * | 1990-11-13 | 1991-10-22 | American Cyanamid Company | Process for the synthesis of α-[(dialkylamino)substituted-methylene]-β-oxo-(substituted)propanentriles |
ES2036136B1 (es) * | 1991-10-16 | 1994-03-01 | Inke Sa | Procedimiento para la obtencion del acido 1-(2,4-difluorofenil)-6-fluoro-7-(3-metilpiperacinil)-4-oxo-1, 4-dihidroquinolin-3-carboxilico y sus sales. |
DE10021900A1 (de) | 2000-05-08 | 2001-11-15 | Bayer Ag | Phenyl-substituierte 2-Enamino-Ketonitrile |
US7778203B2 (en) | 2008-02-01 | 2010-08-17 | Microsoft Corporation | On-demand MAC address lookup |
CN101456825B (zh) * | 2008-12-30 | 2012-01-11 | 浙江国邦药业有限公司 | 一种丙烯腈衍生物的制备方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2726947A (en) * | 1950-12-22 | 1955-12-13 | Goodrich Co B F | Herbicidal compositions comprising alkyl polychlorobenzoates |
GB830832A (en) * | 1957-02-15 | 1960-03-23 | Ici Ltd | New quinolones and therapeutic compositions containing them |
US3047574A (en) * | 1960-03-28 | 1962-07-31 | Searle & Co | 2-cyclohexyl-4-(2-hydroxyethyl)-3-methylmorpholine esters of substituted benzoic acids |
NL7101049A (xx) * | 1970-01-28 | 1971-07-30 | ||
US4309566A (en) * | 1979-11-05 | 1982-01-05 | Fmc Corporation | Plant regulator |
DE3036967A1 (de) * | 1980-10-01 | 1982-05-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 3-brom-4-fluor-benzylalkohol und neue zwischenprodukte hierfuer |
DE3141659A1 (de) * | 1981-10-21 | 1983-05-05 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von in o-stellung substituierten fluoraromaten |
US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
DE3248506A1 (de) * | 1982-12-29 | 1984-07-05 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
DE3248507A1 (de) * | 1982-12-29 | 1984-07-05 | Bayer Ag, 5090 Leverkusen | Mikrobizide mittel auf chinoloncarbonsaeure basis |
US4529725A (en) * | 1984-04-26 | 1985-07-16 | Abbott Laboratories | 1-Pyridine substituted quino-benzothiazine |
DE3426483A1 (de) * | 1984-07-18 | 1986-01-30 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von halogenierten chinoloncarbonsaeuren |
US4686221A (en) * | 1985-10-01 | 1987-08-11 | Kanebo, Ltd. | Quinolinecarboxylic acid compounds and antimicrobial agent containing the same |
-
1984
- 1984-07-18 DE DE3426483A patent/DE3426483A1/de not_active Withdrawn
-
1985
- 1985-06-28 CA CA000486146A patent/CA1273936A/en not_active Expired - Lifetime
- 1985-07-08 EP EP85108421A patent/EP0168737A3/de not_active Withdrawn
- 1985-07-12 US US06/754,563 patent/US4680401A/en not_active Expired - Fee Related
- 1985-07-15 IL IL75812A patent/IL75812A/xx unknown
- 1985-07-16 KR KR1019850005069A patent/KR910003616B1/ko not_active IP Right Cessation
- 1985-07-16 ES ES545255A patent/ES8604522A1/es not_active Expired
- 1985-07-16 DD DD85278634A patent/DD236524A5/de not_active IP Right Cessation
- 1985-07-17 HU HU872465A patent/HU195488B/hu not_active IP Right Cessation
- 1985-07-17 DK DK325685A patent/DK325685A/da not_active Application Discontinuation
- 1985-07-17 ZA ZA855385A patent/ZA855385B/xx unknown
- 1985-07-17 HU HU852747A patent/HU194177B/hu not_active IP Right Cessation
- 1985-07-17 JP JP15617085A patent/JPS6136265A/ja active Pending
-
1987
- 1987-03-24 US US07/029,939 patent/US4782156A/en not_active Expired - Fee Related
-
1988
- 1988-06-21 US US07/209,751 patent/US4914228A/en not_active Expired - Fee Related
-
1990
- 1990-01-19 US US07/467,630 patent/US4990646A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HU195488B (en) | 1988-05-30 |
ES8604522A1 (es) | 1986-02-01 |
DE3426483A1 (de) | 1986-01-30 |
US4782156A (en) | 1988-11-01 |
US4914228A (en) | 1990-04-03 |
DK325685A (da) | 1986-01-19 |
ZA855385B (en) | 1986-02-26 |
DD236524A5 (de) | 1986-06-11 |
US4990646A (en) | 1991-02-05 |
HUT38911A (en) | 1986-07-28 |
US4680401A (en) | 1987-07-14 |
EP0168737A2 (de) | 1986-01-22 |
EP0168737A3 (de) | 1987-11-25 |
KR860001070A (ko) | 1986-02-22 |
CA1273936A (en) | 1990-09-11 |
IL75812A0 (en) | 1985-11-29 |
KR910003616B1 (ko) | 1991-06-07 |
ES545255A0 (es) | 1986-02-01 |
JPS6136265A (ja) | 1986-02-20 |
HU194177B (en) | 1988-01-28 |
DK325685D0 (da) | 1985-07-17 |
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