IL75509A0 - Process for n-demethylation of morphinane alkaloids - Google Patents

Process for n-demethylation of morphinane alkaloids

Info

Publication number
IL75509A0
IL75509A0 IL75509A IL7550985A IL75509A0 IL 75509 A0 IL75509 A0 IL 75509A0 IL 75509 A IL75509 A IL 75509A IL 7550985 A IL7550985 A IL 7550985A IL 75509 A0 IL75509 A0 IL 75509A0
Authority
IL
Israel
Prior art keywords
group
hydrogen atom
carbon atoms
benzoyloxy
acyloxy
Prior art date
Application number
IL75509A
Other languages
English (en)
Original Assignee
Alkaloida Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar filed Critical Alkaloida Vegyeszeti Gyar
Publication of IL75509A0 publication Critical patent/IL75509A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Materials For Photolithography (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cephalosporin Compounds (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Stringed Musical Instruments (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Finger-Pressure Massage (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL75509A 1984-07-17 1985-06-13 Process for n-demethylation of morphinane alkaloids IL75509A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU842774A HU197750B (en) 1984-07-17 1984-07-17 Process for n-demethylation of morphine alkaloids

Publications (1)

Publication Number Publication Date
IL75509A0 true IL75509A0 (en) 1985-10-31

Family

ID=10961043

Family Applications (2)

Application Number Title Priority Date Filing Date
IL75509A IL75509A0 (en) 1984-07-17 1985-06-13 Process for n-demethylation of morphinane alkaloids
IL78503A IL78503A (en) 1984-07-17 1986-04-15 Preparation of(4,5-epoxy)morphinan-6-one hydrazones and semi(thio)carbazones

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL78503A IL78503A (en) 1984-07-17 1986-04-15 Preparation of(4,5-epoxy)morphinan-6-one hydrazones and semi(thio)carbazones

Country Status (18)

Country Link
EP (1) EP0168686B1 (fi)
JP (1) JPS6193184A (fi)
AT (1) ATE41933T1 (fi)
BG (1) BG44029A3 (fi)
CS (1) CS251792B2 (fi)
DD (1) DD235639A5 (fi)
DE (1) DE3569244D1 (fi)
DK (1) DK322385A (fi)
ES (1) ES8603716A1 (fi)
FI (1) FI81583C (fi)
HU (1) HU197750B (fi)
IL (2) IL75509A0 (fi)
IN (1) IN166255B (fi)
NO (1) NO161915C (fi)
PL (1) PL254552A1 (fi)
RO (1) RO91516B (fi)
SU (1) SU1398776A3 (fi)
YU (1) YU45264B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ586187A (en) * 2007-12-17 2013-07-26 Mallinckrodt Llc Processes for the synthesis of sinomenine derivatives and their intermediate
JP5688974B2 (ja) * 2007-12-17 2015-03-25 マリンクロッド エルエルシー （＋）−オピエートの生成のためのプロセスおよび化合物
WO2010132570A1 (en) * 2009-05-12 2010-11-18 Board Of Regents The University Of Texas System Synthesis of morphine and related derivatives
US9562014B2 (en) * 2009-07-16 2017-02-07 Mallinckrodt Llc (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
CN103917543A (zh) 2011-09-08 2014-07-09 马林克罗特有限公司 在不分离中间体的情况下制备生物碱

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA948198A (en) * 1967-08-04 1974-05-28 Gerhard Walther Production of cyclic amino compounds
DE2254298A1 (de) * 1972-11-06 1974-05-16 Boehringer Sohn Ingelheim Neue (heteroarylmethyl)-normorphine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
DE2727805A1 (de) * 1977-06-21 1979-01-04 Goedecke Ag Verfahren zur herstellung von oxynormorphon

Also Published As

Publication number Publication date
RO91516A (ro) 1987-06-30
DD235639A5 (de) 1986-05-14
IN166255B (fi) 1990-03-31
FI81583B (fi) 1990-07-31
DK322385A (da) 1986-01-18
ES8603716A1 (es) 1986-01-16
FI852779A0 (fi) 1985-07-15
JPS6193184A (ja) 1986-05-12
RO91516B (ro) 1987-07-01
CS251792B2 (en) 1987-08-13
YU117485A (en) 1988-04-30
NO161915B (no) 1989-07-03
BG44029A3 (en) 1988-09-15
FI81583C (fi) 1990-11-12
EP0168686A1 (de) 1986-01-22
ES544385A0 (es) 1986-01-16
PL254552A1 (en) 1986-07-15
NO161915C (no) 1989-10-11
NO852838L (no) 1986-01-20
IL78503A (en) 1990-01-18
HUT38645A (en) 1986-06-30
DE3569244D1 (en) 1989-05-11
YU45264B (en) 1992-05-28
EP0168686B1 (de) 1989-04-05
SU1398776A3 (ru) 1988-06-15
HU197750B (en) 1989-05-29
ATE41933T1 (de) 1989-04-15
DK322385D0 (da) 1985-07-15
FI852779L (fi) 1986-01-18
CS528085A2 (en) 1986-12-18

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Legal Events

Date Code Title Description
RH Patent void